Regulation of TGF-β Family Signaling by Inhibitory Smads

10.1006/bbrc.1998.9170

10.1158/0008-5472.CAN-03-2999

10.1172/JCI200416269

10.1093/jnci/dji399

10.1038/35003228

10.1074/jbc.M105105200

10.1074/jbc.275.12.8267

10.1016/j.molcel.2004.07.021

10.1128/MCB.23.18.6646-6661.2003

10.1093/jb/mvt020

10.1074/jbc.C400579200

2000, A mechanism of suppression of TGF-β/SMAD signaling by NF-κB/RelA, Genes Dev, 14, 187, 10.1101/gad.14.2.187

10.1002/ijc.10908

10.1523/JNEUROSCI.0991-13.2013

10.1016/j.bbrc.2006.01.041

10.1038/ng.2007.18

10.1074/jbc.M002815200

10.1074/jbc.M807233200

10.2337/db10-0403

10.1038/ni1383

2009, Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice, Nephrol Dial Transplant, 24, 1143

10.1113/JP270201

10.1128/MCB.20.9.3157-3167.2000

10.1038/nature07086

10.1074/jbc.M404961200

10.1073/pnas.090099297

10.1074/jbc.C100008200

10.1091/mbc.02-03-0037

10.1242/jcs.01036

10.1128/MCB.25.4.1475-1488.2005

10.1038/nm.2619

10.1016/j.ydbio.2013.04.003

10.2337/db13-0432

10.1038/35071095

10.1002/jbmr.443

2013, Smad7 regulates terminal maturation of chondrocytes in the growth plate, Dev Biol, 15, 375

10.4049/jimmunol.172.9.5149

10.1038/sj.onc.1205623

10.1073/pnas.0400035101

10.1038/72835

10.1038/sj.onc.1209436

10.1074/jbc.M702100200

10.1016/S1097-2765(03)00386-1

10.1016/S1097-2765(02)00639-1

10.1093/jmcb/mjt017

10.1111/j.1582-4934.2008.00262.x

10.1016/j.ajpath.2011.06.003

10.1038/nm.3118

10.1083/jcb.200106023

10.1038/40431

10.1101/gad.12.2.186

10.1016/S0092-8674(00)81561-5

10.1128/MCB.00274-15

10.1016/S0092-8674(00)80303-7

10.1093/emboj/21.11.2580

10.1038/ni1451

10.1074/jbc.M112.400408

10.1083/jcb.200311015

10.1074/jbc.C000568200

10.1172/JCI200214685

10.1186/1471-2121-5-2

10.1074/jbc.M509338200

10.1038/39355

10.1016/j.febslet.2006.11.008

10.1091/mbc.9.8.2145

10.1074/jbc.275.9.6075

10.1074/jbc.273.44.29195

10.1093/emboj/20.15.4132

10.1038/nm1282

10.1038/sj.onc.1205681

10.1074/jbc.M204812200

2013, Smad6 inhibits non-canonical TGF-β1 signalling by recruiting the deubiquitinase A20 to TRAF6, Nat Commun, 4, 2562, 10.1038/ncomms3562

10.1074/jbc.M110.166140

10.1074/jbc.M105302200

10.1016/S1097-2765(00)00134-9

10.1128/MCB.24.6.2251-2262.2004

10.1093/annonc/mdh131

10.1111/j.1365-2567.2010.03269.x

10.1242/jcs.136028

10.1038/sj.onc.1202909

10.1006/bbrc.1999.0171

10.1093/brain/awq039

10.1093/emboj/cdg632

10.1074/jbc.M111.227561

10.1128/MCB.00384-06

10.1038/sj.onc.1207885

10.1083/jcb.200804107

10.1128/MCB.00434-09

1992, Transcriptional activation of the tumor necrosis factor α-inducible zinc finger protein, A20, is mediated by κB elements, J Biol Chem, 267, 17971, 10.1016/S0021-9258(19)37138-8

10.1046/j.1440-169X.2001.00562.x

10.1016/j.diff.2012.04.003

10.1074/jbc.M510004200

10.1073/pnas.0508977103

10.1074/jbc.M605904200

10.1042/BJ20040738

10.1038/sj.onc.1204167

10.1074/jbc.M500188200

10.1016/S0960-9822(00)00470-X

10.1146/annurev.cellbio.20.012103.135836

10.1038/ncomms1469

10.15252/emmm.201404653

10.1158/0008-5472.CAN-07-6793

10.1128/MCB.00664-07

10.1038/sj.onc.1207319

10.4049/jimmunol.176.11.6777

2013, MiR-21/Smad 7 signaling determines TGF-β1-induced CAF formation, Sci Rep, 10, 1038

10.1074/jbc.C000580200

10.1128/MCB.23.24.9081-9093.2003

2003, Smad7 but not Smad6 cooperates with oncogenic ras to cause malignant conversion in a mouse model for squamous cell carcinoma, Cancer Res, 63, 7760

10.1038/sj.emboj.7601057

10.1084/jem.20100035

10.1371/journal.pone.0053573

10.1074/jbc.M111.307249

10.1038/sj.emboj.7600067

10.1074/jbc.M101672200

10.1016/S1097-2765(00)80331-7

2001, BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation, Development, 128, 4523, 10.1242/dev.128.22.4523

10.1128/MCB.01005-09

2000, Positive and negative regulation of TGF-β signaling, J Cell Sci, 113, 1101, 10.1242/jcs.113.7.1101

Miyazono K . 2008. Regulation of TGF-β family signaling by inhibitory Smads. In The TGF-β family (ed. Derynck R , Miyazono K ), pp. 363–387. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.

10.1074/jbc.M313977200

10.1172/JCI200112821

10.1074/jbc.M303654200

10.1016/j.it.2004.07.008

10.1053/j.gastro.2003.11.048

10.1056/NEJMoa1407250

10.1091/mbc.E02-07-0441

10.1074/jbc.M701294200

10.1074/jbc.274.47.33412

10.1038/39369

10.1172/JCI6094

10.1084/jem.192.2.151

10.1046/j.1365-2443.1998.00196.x

1998, Xenopus Smad8 acts downstream of BMP-4 to modulate its activity during vertebrate embryonic patterning, Development, 125, 857, 10.1242/dev.125.5.857

10.1016/S0925-4773(00)00533-5

10.1038/35071103

10.1038/18465

10.1016/j.molcel.2005.06.028

10.1038/46794

Padgett RW , Patterson GI . 2006. C. elegans TGF-β signaling pathways. In Smad signal transduction (ed. ten Dijke P , Heldin CH ), pp. 37–53. Springer, Amsterdam, The Netherlands.

2014, microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial-mesenchymal transition, Nat Commun, 5, 2977, 10.1038/ncomms3977

2004, Expression of Smad7 in hepatocellular carcinoma and dysplastic nodules: Resistance mechanism to transforming growth factor-β, Hepatogastroenterology, 51, 396

10.1074/jbc.M004861200

10.1101/gr.092668.109

10.1074/jbc.M011019200

10.1074/jbc.M409647200

10.1016/S0002-9440(10)62358-9

10.1074/jbc.C200543200

10.1172/JCI200112367

10.1038/sj.emboj.7600398

10.1074/jbc.M110.138370

10.1074/jbc.M506761200

10.1016/S0092-8674(03)00432-X

10.1083/jcb.200307151

10.1101/gad.1360605

10.1074/jbc.M503134200

10.1158/0008-5472.CAN-08-1792

10.1038/onc.2012.11

10.1038/ncb1780

10.1074/jbc.273.39.25364

10.1074/jbc.M201901200

10.1074/jbc.M212663200

10.1002/humu.22030

2002, Gene transfer of Smad7 using electroporation of adenovirus prevents renal fibrosis in post-obstructed kidney, Kidney Int, 61, 94, 10.1046/j.1523-1755.2002.0610s1094.x

1999, Antivin, a novel and divergent member of the TGFβ superfamily, negatively regulates mesoderm induction, Development, 126, 229, 10.1242/dev.126.2.229

10.1093/jb/mvs022

10.1073/pnas.94.17.9314

10.1093/jb/mvv024

10.1038/39362

10.1038/17826

10.1074/jbc.M202086200

10.1186/1471-2121-7-16

1988, Chemical and biological characterization of the inhibin family of protein hormones, Recent Prog Horm Res, 44, 1

2006, Transforming growth factor-β1 is a negative modulator of adult neurogenesis, J Neuropathol Exp Neurol, 65, 358, 10.1097/01.jnen.0000218444.53405.f0

10.1093/embo-reports/kvf024

10.1074/jbc.M411575200

10.1038/onc.2008.291

10.1002/path.4206

10.1371/journal.pone.0070195

10.4049/jimmunol.176.3.1316

10.1074/jbc.M309798200

10.1002/hep.26369

2014, M2 macrophages promote β-cell proliferation by up-regulation of SMAD7, Proc Natl Acad Sci, 111, 1211, 10.1073/pnas.1321347111

10.1073/pnas.1100160108

10.1016/j.molcel.2013.05.004

10.1126/science.270.5244.2008

10.1074/jbc.M006023200

10.1016/j.molcel.2008.09.002

10.1074/jbc.M109.049304

10.1128/MCB.05448-11

2014, Yin Yang 1 (YY1) synergizes with Smad7 to inhibit TGF-β signaling in the nucleus, Sci China Life Sci, 57, 128, 10.1007/s11427-013-4581-2

10.1074/jbc.M115.694281

10.1016/S0092-8674(00)00211-7

10.1016/S0925-4773(03)00020-0

10.1038/cr.2008.328

2001, Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase, Proc Natl Acad Sci, 98, 97497

10.1128/MCB.01636-06

10.1016/j.molcel.2012.04.003

10.1074/jbc.M112.416719

10.1038/emboj.2013.38

10.1038/ncomms4388

10.1038/23293

10.1371/journal.pone.0017415

10.1074/jbc.M112.388009