Regulation of Neuronal Glutathione Synthesis
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3 Dringen R. Metabolism and functions of glutathione in brain. Prog Neurobiol. 2000;62:649–671.
4 Chance B, Sies H, Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol Rev. 1979;59:527–605.
5 Youdim MB, Ben-Shachar D, Riederer P. Is Parkinson’s disease a progressive siderosis of substantia nigra resulting in iron and melanin induced neurodegeneration? Acta Neurol Scand Suppl. 1989;126:47–54.
1995, 47, 271
15 Genovese T, Mazzon E, Esposito E, Muia C, Di Paola R, Di Bella P, et al. Role of endogenous glutathione in the secondary damage in experimental spinal cord injury in mice. Neurosci Lett. 2007;423:41–46.
1997, 378, 793
23 Maher P. The effects of stress and aging on glutathione metabolism. Ageing Res Rev. 2005;4:288–314.
25 Xie C, Lovell MA, Markesbery WR. Glutathione transferase protects neuronal cultures against four hydroxynonenal toxicity. Free Radic Biol Med. 1998;25:979–988.
31 Rauhala P, Lin AM, Chiueh CC. Neuroprotection by S-nitrosoglutathione of brain dopamine neurons from oxidative stress. FASEB J. 1998;12:165–173.
33 Sagara J, Makino N. Glutathione induces neuronal differentiation in rat bone marrow stromal cells. Neurochem Res. 2008;33:16–21.
1995, 1271, 35
36 Richman PG, Meister A. Regulation of gamma-glutamyl-cysteine synthetase by nonallosteric feedback inhibition by glutathione. J Biol Chem. 1975;250:1422–1426.
38 Dalton TP, Chen Y, Schneider SN, Nebert DW, Shertzer HG. Genetically altered mice to evaluate glutathione homeostasis in health and disease. Free Radic Biol Med. 2004;37:1511–1526.
44 Hogstad S, Svenneby G, Torgner IA, Kvamme E, Hertz L, Schousboe A. Glutaminase in neurons and astrocytes cultured from mouse brain: kinetic properties and effects of phosphate, glutamate, and ammonia. Neurochem Res. 1988;13:383–388.
55 Dringen R, Hamprecht B. Glutathione restoration as indicator for cellular metabolism of astroglial cells. Dev Neurosci. 1998;20:401–407.
59 Rana S, Dringen R. Gap junction hemichannel-mediated release of glutathione from cultured rat astrocytes. Neurosci Lett. 2007;415:45–48.
60 Dringen R, Gutterer JM, Gros C, Hirrlinger J. Aminopeptidase N mediates the utilization of the GSH precursor CysGly by cultured neurons. J Neurosci Res. 2001;66:1003–1008.
61 Shih AY, Erb H, Sun X, Toda S, Kalivas PW, Murphy TH. Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation. J Neurosci. 2006;26:10514–10523.
63 Pow DV. Visualising the activity of the cystine-glutamate antiporter in glial cells using antibodies to aminoadipic acid, a selectively transported substrate. Glia. 2001;34:27–38.
64 Qin S, Colin C, Hinners I, Gervais A, Cheret C, Mallat M. System Xc- and apolipoprotein E expressed by microglia have opposite effects on the neurotoxicity of amyloid-beta peptide 1-40. J Neurosci. 2006;26:3345–3356.
66 Sato H, Tamba M, Okuno S, Sato K, Keino-Masu K, Masu M, et al. Distribution of cystine/glutamate exchange transporter, system x(c)-, in the mouse brain. J Neurosci. 2002;22:8028–8033.
68 Murphy TH, Schnaar RL, Coyle JT. Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake. FASEB J. 1990;4:1624–1633.
69 La Bella V, Valentino F, Piccoli T, Piccoli F. Expression and developmental regulation of the cystine/glutamate exchanger (xc-) in the rat. Neurochem Res. 2007;32:1081–1090.
72 Koch HP, Larsson HP. Small-scale molecular motions accomplish glutamate uptake in human glutamate transporters. J Neurosci. 2005;25:1730–1736.
74 Rothstein JD, Dykes-Hoberg M, Pardo CA, Bristol LA, Jin L, Kuncl RW, et al. Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron. 1996;16:675–686.
76 Zerangue N, Kavanaugh MP. Interaction of L-cysteine with a human excitatory amino acid transporter. J Physiol. 1996;493 (Pt 2):419–423.
79 Schniepp R, Kohler K, Ladewig T, Guenther E, Henke G, Palmada M, et al. Retinal colocalization and in vitro interaction of the glutamate transporter EAAT3 and the serum- and glucocorticoid-inducible kinase SGK1 [correction]. Invest Ophthalmol Vis Sci. 2004;45:1442–1449.
81 Xia P, Pei G, Schwarz W. Regulation of the glutamate transporter EAAC1 by expression and activation of delta-opioid receptor. Eur J Neurosci. 2006;24:87–93.
82 Lin CI, Orlov I, Ruggiero AM, Dykes-Hoberg M, Lee A, Jackson M, et al. Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18. Nature. 2001;410:84–88.
83 Krizman-Genda E, Gonzalez MI, Zelenaia O, Robinson MB. Evidence that Akt mediates platelet-derived growth factor-dependent increases in activity and surface expression of the neuronal glutamate transporter, EAAC1. Neuropharmacology. 2005;49:872–882.
85 Gonzalez MI, Kazanietz MG, Robinson MB. Regulation of the neuronal glutamate transporter excitatory amino acid carrier-1 (EAAC1) by different protein kinase C subtypes. Mol Pharmacol. 2002;62:901–910.
90 Maier S, Reiterer V, Ruggiero AM, Rothstein JD, Thomas S, Dahm R, et al. GTRAP3-18 serves as a negative regulator of Rab1 in protein transport and neuronal differentiation. J Cell Mol Med. In press 2008.
91 Bianchi MG, Gazzola GC, Tognazzi L, Bussolati O. C6 glioma cells differentiated by retinoic acid overexpress the glutamate transporter excitatory amino acid carrier 1 (EAAC1). Neuroscience. 2008;151:1042–1052.
94 Wang NP, Zhou JW, Li AP, Cao HX, Wang XR. [The mechanism of JWA gene involved in oxidative stress of cells.] Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2003;21:212–215. (text in Chinese with English abstract)
95 Mao WG, Li AP, Ye J, Huang S, Li AQ, Zhou JW. [Expressions of JWA protein and heat stress protein 70 induced by cell differentiation inducers combined with heat stress in K562 cells.] Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2004;22:60–63. (text in Chinese with English abstract)
96 Watabe M, Aoyama K, Nakaki T. Regulation of glutathione synthesis via interaction between glutamate transport-associated protein 3-18 (GTRAP3-18) and excitatory amino acid carrier-1 (EAAC1) at plasma membrane. Mol Pharmacol. 2007;72:1103–1110.
97 Watabe M, Aoyama K, Nakaki T. A dominant role of GTRAP3-18 in neuronal glutathione synthesis. J Neurosci. 2008;28:9404–9413.
98 Aebi S, Assereto R, Lauterburg BH. High-dose intravenous glutathione in man. Pharmacokinetics and effects on cyst(e)ine in plasma and urine. Eur J Clin Invest. 1991;21:103–110.
99 Cornford EM, Braun LD, Crane PD, Oldendorf WH. Blood-brain barrier restriction of peptides and the low uptake of enkephalins. Endocrinology. 1978;103:1297–1303.
100 Zeevalk GD, Manzino L, Sonsalla PK, Bernard LP. Characterization of intracellular elevation of glutathione (GSH) with glutathione monoethyl ester and GSH in brain and neuronal cultures: relevance to Parkinson’s disease. Exp Neurol. 2007;203:512–520.
103 Tsan MF, White JE, Rosano CL. Modulation of endothelial GSH concentrations: effect of exogenous GSH and GSH monoethyl ester. J Appl Physiol. 1989;66:1029–1034.
1994, 664, 133
107 De Flora S, Izzotti A, D’Agostini F, Cesarone CF. Antioxidant activity and other mechanisms of thiols involved in chemoprevention of mutation and cancer. Am J Med. 1991;91:122S–130S.
108 Sekhon B, Sekhon C, Khan M, Patel SJ, Singh I, Singh AK. N-Acetyl cysteine protects against injury in a rat model of focal cerebral ischemia. Brain Res. 2003;971:1–8.
109 Hart AM, Terenghi G, Kellerth JO, Wiberg M. Sensory neuroprotection, mitochondrial preservation, and therapeutic potential of N-acetyl-cysteine after nerve injury. Neuroscience. 2004;125:91–101.
110 Aoyama K, Matsumura N, Watabe M, Nakaki T. Oxidative stress on EAAC1 is involved in MPTP-induced glutathione depletion and motor dysfunction. Eur J Neurosci. 2008;27:20–30.
111 Andersen JK. Oxidative stress in neurodegeneration: cause or consequence? Nat Med. 2004;10 Suppl:S18–S25.
112 Odetti P, Garibaldi S, Norese R, Angelini G, Marinelli L, Valentini S, et al. Lipoperoxidation is selectively involved in progressive supranuclear palsy. J Neuropathol Exp Neurol. 2000;59:393–397.
115 Ramassamy C, Averill D, Beffert U, Theroux L, Lussier-Cacan S, Cohn JS, et al. Oxidative insults are associated with apolipoprotein E genotype in Alzheimer’s disease brain. Neurobiol Dis. 2000;7:23–37.
117 Lovell MA, Xie C, Markesbery WR. Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimer’s disease. Neurology. 1998;51:1562–1566.
120 Albers DS, Augood SJ. New insights into progressive supranuclear palsy. Trends Neurosci. 2001;24:347–353.
121 Fitzmaurice PS, Ang L, Guttman M, Rajput AH, Furukawa Y, Kish SJ. Nigral glutathione deficiency is not specific for idiopathic Parkinson’s disease. Mov Disord. 2003;18:969–976.
123 Kang Y, Viswanath V, Jha N, Qiao X, Mo JQ, Andersen JK. Brain gamma-glutamyl cysteine synthetase (GCS) mRNA expression patterns correlate with regional-specific enzyme activities and glutathione levels. J Neurosci Res. 1999;58:436–441.
126 Trinh K, Moore K, Wes PD, Muchowski PJ, Dey J, Andrews L, et al. Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson’s disease. J Neurosci. 2008;28:465–472.
127 Trotti D, Danbolt NC, Volterra A. Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration? Trends Pharmacol Sci. 1998;19:328–334.
128 Plaitakis A, Shashidharan P. Glutamate transport and metabolism in dopaminergic neurons of substantia nigra: implications for the pathogenesis of Parkinson’s disease. J Neurol. 2000;247 Suppl 2:II25–II35.
129 Berman AE, Chan WY, Brennan AM, Swanson RA. Age-dependent dopaminergic cell loss and nitration of α-synuclein in the substantia nigra of EAAC1−/− mice. Soc Neurosci Abstr. 2007;33:370.3.
131 Matsumura N, Kikuchi-Utsumi K, Nakaki T. Activities of 7-nitroindazole and 1-(2-(trifluoromethylphenyl)-imidazole independent of neuronal nitric-oxide synthase inhibition. J Pharmacol Exp Ther. 2008;325:357–362.