Regulation of Cell Signaling Dynamics by the Protein Kinase-Scaffold Ste5

Molecular Cell - Tập 30 - Trang 649-656 - 2008
Nan Hao1, Sujata Nayak2, Marcelo Behar3, Ryan H. Shanks1, Michal J. Nagiec1, Beverly Errede4, Jeffrey Hasty5, Timothy C. Elston1, Henrik G. Dohlman1,4
1Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
2Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA
3Department of Physics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
4Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 USA
5Department of Bioengineering, University of California, San Diego, La Jolla, CA, 92093, USA

Tài liệu tham khảo

Andersson, 2004, Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes, EMBO J., 23, 2564, 10.1038/sj.emboj.7600250 Bhattacharyya, 2006, The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway, Science, 311, 822, 10.1126/science.1120941 Breitkreutz, 2001, MAPK specificity in the yeast pheromone response independent of transcriptional activation, Curr. Biol., 11, 1266, 10.1016/S0960-9822(01)00370-0 Choi, 1994, Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae, Cell, 78, 499, 10.1016/0092-8674(94)90427-8 Cook, 1997, Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway, Nature, 390, 85, 10.1038/36355 Dorer, 1995, Saccharomyces cerevisiae cells execute a default pathway to select a mate in the absence of pheromone gradients, J. Cell Biol., 131, 845, 10.1083/jcb.131.4.845 Erdman, 2001, A filamentous growth response mediated by the yeast mating pathway, Genetics, 159, 919, 10.1093/genetics/159.3.919 Ferrell, 1998, The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes, Science, 280, 895, 10.1126/science.280.5365.895 Flatauer, 2005, Mitogen-activated protein kinases with distinct requirements for Ste5 scaffolding influence signaling specificity in Saccharomyces cerevisiae, Mol. Cell. Biol., 25, 1793, 10.1128/MCB.25.5.1793-1803.2005 Gartner, 1992, Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1, Genes Dev., 6, 1280, 10.1101/gad.6.7.1280 Goldbeter, 1981, An amplified sensitivity arising from covalent modification in biological systems, Proc. Natl. Acad. Sci. USA, 78, 6840, 10.1073/pnas.78.11.6840 Koshland, 1982, Amplification and adaptation in regulatory and sensory systems, Science, 217, 220, 10.1126/science.7089556 Kusari, 2004, A conserved protein interaction network involving the yeast MAP kinases Fus3 and Kss1, J. Cell Biol., 164, 267, 10.1083/jcb.200310021 Liu, 1993, Elements of the yeast pheromone response pathway required for filamentous growth of diploids, Science, 262, 1741, 10.1126/science.8259520 Madden, 1992, Specification of sites for polarized growth in Saccharomyces cerevisiae and the influence of external factors on site selection, Mol. Biol. Cell, 3, 1025, 10.1091/mbc.3.9.1025 Madhani, 1997, Combinatorial control required for the specificity of yeast MAPK signaling, Science, 275, 1314, 10.1126/science.275.5304.1314 Maeder, 2007, Spatial regulation of Fus3 MAP kinase activity through a reaction-diffusion mechanism in yeast pheromone signalling, Nat. Cell Biol., 9, 1319, 10.1038/ncb1652 Maleri, 2004, Persistent activation by constitutive Ste7 promotes Kss1-mediated invasive growth but fails to support Fus3-dependent mating in yeast, Mol. Cell. Biol., 24, 9221, 10.1128/MCB.24.20.9221-9238.2004 Marshall, 1995, Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation, Cell, 80, 179, 10.1016/0092-8674(95)90401-8 Nern, 1998, A GTP-exchange factor required for cell orientation, Nature, 391, 195, 10.1038/34458 Paliwal, 2007, MAPK-mediated bimodal gene expression and adaptive gradient sensing in yeast, Nature, 446, 46, 10.1038/nature05561 Poritz, 2001, Graded mode of transcriptional induction in yeast pheromone signalling revealed by single-cell analysis, Yeast, 18, 1331, 10.1002/yea.777 Printen, 1994, Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade, Genetics, 138, 609, 10.1093/genetics/138.3.609 Roberts, 1994, Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: mating and invasive growth, Genes Dev., 8, 2974, 10.1101/gad.8.24.2974 Roberts, 2000, Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles, Science, 287, 873, 10.1126/science.287.5454.873 Sabbagh, 2001, Specificity of MAP kinase signaling in yeast differentiation involves transient versus sustained MAPK activation, Mol. Cell, 8, 683, 10.1016/S1097-2765(01)00322-7 Segall, 1993, Polarization of yeast cells in spatial gradients of alpha mating factor, Proc. Natl. Acad. Sci. USA, 90, 8332, 10.1073/pnas.90.18.8332 Sette, 2000, Mutational analysis suggests that activation of the yeast pheromone response mitogen-activated protein kinase pathway involves conformational changes in the ste5 scaffold protein, Mol. Biol. Cell, 11, 4033, 10.1091/mbc.11.11.4033 Strickfaden, 2007, Distinct roles for two G{alpha}-G{beta} interfaces in cell polarity control by a yeast heterotrimeric G protein, Mol. Biol. Cell, 19, 181, 10.1091/mbc.e07-04-0385 Valtz, 1995, FAR1 is required for oriented polarization of yeast cells in response to mating pheromones, J. Cell Biol., 131, 863, 10.1083/jcb.131.4.863 Wang, 2004, Pheromone signaling mechanisms in yeast: a prototypical sex machine, Science, 306, 1508, 10.1126/science.1104568