Regional Cerebral Blood Flow During Script-Driven Imagery in Childhood Sexual Abuse-Related PTSD: A PET Investigation

American Journal of Psychiatry - Tập 156 Số 4 - Trang 575-584 - 1999
Lisa M. Shin1, Richard J. McNally, Stephen M. Kosslyn, William L. Thompson, Scott L. Rauch, Nathaniel M. Alpert, Linda J. Metzger, Natasha B. Lasko, Scott P. Orr, Roger K. Pitman
1Department of Psychiatry, Massachusetts General Hospital, Boston, USA. [email protected]

Tóm tắt

Từ khóa


Tài liệu tham khảo

Orr SP, Lasko NB, Metzger LJ, Ahern CE, Berry NJ, Pitman RK: Psychophysiologic assessment of women with posttraumatic stress disorder resulting from childhood sexual abuse. J Consult Clin Psychol 1998; 66:906–913

Pitman RK, Orr SP, Forgue DF, de Jong JB, Claiborn JM: Psychophysiologic assessment of posttraumatic stress disorder imagery in Vietnam combat veterans. Arch Gen Psychiatry 1987; 44:970–975

Pitman RK, Orr SP, Forgue DF, Altman B, de Jong JB, Herz LR: Psychophysiologic responses to combat imagery of Vietnam veterans with posttraumatic stress disorder versus other anxiety disorders. J Abnorm Psychol 1990; 99:49–54

Lang PJ, Levin DN, Miller GA, Kozak MJ: Fear behavior, fear imagery, and the psychophysiology of emotion: the problem of affective response integration. J Abnorm Psychol 1983; 92:276–306

Rauch SL, van der Kolk BA, Fisler RE, Alpert NM, Orr SP, Savage CR, Fischman AJ, Jenike MA, Pitman RK: A symptom provocation study of posttraumatic stress disorder using positron emission tomography and script-driven imagery. Arch Gen Psychiatry 1996; 53:380–387

Shin LM, Kosslyn SM, McNally RJ, Alpert NM, Thompson WL, Rauch SL, Macklin ML, Pitman RK: Visual imagery and perception in posttraumatic stress disorder: a positron emission tomographic investigation. Arch Gen Psychiatry 1997; 54:233–241

Fischer H, Wik G, Fredrikson M: Functional neuroanatomy of robbery re-experience: affective memories studied with PET. Neuroreport 1996; 7:2081–2086

Kaada BR, Pribram KH, Epstein JA: Respiratory and vascular responses in monkeys from temporal pole, insula, orbital surface and cingulate gyrus. J Neurophysiol 1949; 12:347–356

Wall PD, Davis GD: Three cerebral cortical systems affecting autonomic function. J Neurophysiol 1951; 14:507–517

George MS, Ketter TA, Parekh PI, Horwitz B, Herscovitch P, Post RM: Brain activity during transient sadness and happiness in healthy women. Am J Psychiatry 1995; 152:341–351

George MS, Ketter TA, Parekh PI, Herscovitch P, Post RM: Gender differences in regional cerebral blood flow during transient self-induced sadness or happiness. Biol Psychiatry 1996; 40:859–871

Pardo JV, Pardo PJ, Raichle ME: Neural correlates of self-induced dysphoria. Am J Psychiatry 1993; 150:713–719

Lane RD, Reiman EM, Ahern GL, Schwartz GE, Davidson RJ: Neuroanatomical correlates of happiness, sadness, and disgust. Am J Psychiatry 1997; 154:926–933

Kosslyn SM, Alpert NM, Thompson WL, Maljkovic V, Weise SB, Chabris C, Hamilton SE, Rauch SL, Buonanno FS: Visual mental imagery activates topographically organized visual cortex: PET investigations. J Cognitive Neuroscience 1993; 5:263–287

Kosslyn SM, Shin LM, Thompson WL, McNally RJ, Rauch SL, Pitman RK, Alpert NM: Neural effects of visualizing and perceiving aversive stimuli: a PET investigation. Neuroreport 1996; 7:1569–1576

Oldfield RC: The assessment and analysis of handedness: the Edinburgh Inventory. Neuropsychologia 1971; 9:97–113

Blake DD, Weathers FW, Nagy LM, Kaloupek DG, Klauminzev G, Keane TM: Rating scale for assessing current and lifetime PTSD: the CAPS-I. Behavior Therapist 1990; 13:187–188

Blake DD, Weathers FW, Nagy LM, Kaloupek DG, Gusman FD, Charney DS, Keane TM: The development of a clinician-administered PTSD scale. J Trauma Stress 1995; 8:75–80

Marks DF: Visual imagery differences in the recall of pictures. Br J Psychol 1973; 64:17–24

Friston KJ, Frith CD, Liddle PF, Frakowiak RSJ: Comparing functional (PET) images: the assessment of significant change. J Cereb Blood Flow Metab 1991; 11:690–699

Friston KJ, Holmes AP, Worsley KJ, Poline J-P, Frith CD, Frackowiak RSJ: Statistical parametric maps in functional imaging: a general approach. Human Brain Mapping 1995; 2:189–210

Ketter TA, Andreason PJ, George MS, Lee C, Gill DS, Parekh PI, Willis MW, Herscovitch P, Post RM: Anterior paralimbic mediation of procaine-induced emotional and psychosensory experiences. Arch Gen Psychiatry 1996; 53:59–69

Paradiso S, Robinson RG, Andreasen NC, Downhill JE, Davidson RJ, Kirchner PT, Watkins GL, Boles Ponto LL, Hichwa RD: Emotional activation of limbic circuitry in elderly normal subjects in a PET study. Am J Psychiatry 1997; 154:384–389

Cottraux J, Gérard D, Cinotti L, Froment J-C, Deiber M-P, Le Bars D, Galy G, Millet P, Labbé C, Lavenne F, Bouvard M, Mauguiere F: A controlled positron emission tomography study of obsessive and neutral auditory stimulation in obsessive-compulsive disorder with checking rituals. Psychiatry Res 1996; 60:101–112

Rauch SL, Savage CR, Alpert NM, Miguel EC, Baer L, Breiter HC, Fischman AJ, Manzo PA, Moretti C, Jenike MA: A positron emission tomographic study of simple phobic symptom provocation. Arch Gen Psychiatry 1995; 52:20–28

Benkelfat C, Bradwejn J, Meyer E, Ellenbogen M, Milot S, Gjedde A, Evans A: Functional neuroanatomy of CCK4-induced anxiety in normal healthy volunteers. Am J Psychiatry 1995; 152:1180–1184

Drevets WC, Videen TO, MacLeod AK, Haller JW, Raichle ME: PET images of blood flow changes during anxiety: correction. Science 1992; 256:1696

Whalen PJ, Bush G, McNally RJ, Wilhelm S, McInerney SC, Jenike MA, Rauch SL: The Emotional Counting Stroop Paradigm: a fMRI probe of the anterior cingulate affective division. Biol Psychiatry 1998; 44:1219–1228

Morris JS, Frith CD, Perrett DI, Rowland D, Young AW, Calder AJ, Dolan RJ: A differential response in the human amygdala to fearful and happy facial expressions. Nature 1996; 383:812–815

Breiter HC, Etcoff NL, Whalen PJ, Kennedy WA, Rauch SL, Buckner RL, Strauss MM, Hyman SE, Rosen BR: Response and habituation of the human amygdala during visual processing of facial expression. Neuron 1996; 17:875–887

Whalen PJ, Rauch SL, Etcoff NL, McInerney SC, Lee MB, Jenike MA: Masked presentations of emotional facial expressions modulate amygdala activity without explicit knowledge. J Neurosci 1998; 18:411–418

Kertesz A, Lesk D, McCabe P: Isotope localization of infarcts in aphasia. Arch Neurol 1977; 34:590–601

Petersen SE, Fox PT, Posner MI, Mintun M, Raichle ME: Positron emission tomographic studies of the processing of single words. J Cognitive Neuroscience 1989; 1:153–170

Paulesu E, Frith CD, Frackowiak RSJ: The neural correlates of the verbal component of working memory. Nature 1993; 362:342–345

McGuire PK, Silbersweig DA, Murray RM, David AS, Frackowiak RSJ, Frith CD: Functional anatomy of inner speech and auditory verbal imagery. Psychol Med 1996; 26:29–38

Schacter DL, Alpert NM, Savage CR, Rauch SL, Albert MS: Conscious recollection and the human hippocampal formation: evidence from positron emission tomography. Proc Natl Acad Sci USA 1996; 93:321–325

Andreasen NC, Arndt S, Cizadlo T, O’Leary DS, Watkins GL, Boles Ponto LL, Hichwa RD: Sample size and statistical power in [15O]H2O studies of human cognition. J Cereb Blood Flow 1996; 16:804–816

Kessler RC, Sonnega A, Bromet E, Hughes M, Nelson CB: Posttraumatic stress disorder in the National Comorbidity Survey. Arch Gen Psychiatry 1995; 52:1048–1060