Reduction in the Initial-Burst Release by Surface Crosslinking of PLGA Microparticles Containing Hydrophilic or Hydrophobic Drugs

Drug Development and Industrial Pharmacy - Tập 31 Số 1 - Trang 43-57 - 2005
Amol J. Thote1, John T. Chappell2, Rajesh Kumar3, Ram B. Gupta4
1Department of Chemical Engineering, Auburn University, AL 36849-5127, USA
2Department of Chemical Engineering, Auburn University, AlabamaUSA
3Alkermes, Inc., 88 Sidney Street, Cambridge, Massachusetts, 02139-4137, USA
4Department of Chemical Engineering, Auburn University, AlabamaUSA; Department of Chemical Engineering, Auburn University, Alabama, 36849-5127, USA

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