Reduced resting state functional connectivity in the hippocampus-midbrain-striatum network of schizophrenia patients

Allen, 2017, Increased resting hippocampal and basal ganglia perfusion in people at ultra high risk for psychosis: replication in a Second Cohort Paul, Schizophr. Bull., 1–9 Allen, 2016, Resting hyperperfusion of the hippocampus, midbrain, and basal ganglia in people at high risk for psychosis, Am. J. Psychiatr., 173, 392, 10.1176/appi.ajp.2015.15040485 Andreasen, 1992, The comprehensive assessment of symptoms and history (CASH), Arch. Gen. Psychiatr., 49, 615, 10.1001/archpsyc.1992.01820080023004 Bossong, 2018, Association of hippocampal glutamate levels with adverse outcomes in individuals at clinical high risk for psychosis, JAMA psychiatry Bossong, 2015, Further human evidence for striatal dopamine release induced by administration of δ9-tetrahydrocannabinol (THC): Selectivity to limbic striatum, Psychopharmacology (Berl), 232, 2723, 10.1007/s00213-015-3915-0 Chase, 2015, Evidence for an anterior-posterior differentiation in the human hippocampal formation revealed by meta-analytic parcellation of fMRI coordinate maps: focus on the subiculum, Neuroimage, 113, 44, 10.1016/j.neuroimage.2015.02.069 Dandash, 2014, Altered striatal functional connectivity in subjects with an at-risk mental state for psychosis, Schizophr. Bull., 40, 904, 10.1093/schbul/sbt093 Floresco, 2003, Afferent modulation of dopamine neuron firing differentially regulates tonic and phasic dopamine transmission, Nat. Neurosci., 6, 968, 10.1038/nn1103 Fornito, 2013, Functional dysconnectivity of corticostriatal Circuitry as a risk Phenotype for psychosis, JAMA Psychiatry, 70, 1143, 10.1001/jamapsychiatry.2013.1976 Gonen, 2016, Human mesostriatal response tracks motivational tendencies under naturalistic goal conflict, Soc. Cognit. Affect Neurosci., 11, 961, 10.1093/scan/nsw014 Grace, 2016, Dysregulation of the dopamine system in the pathophysiology of schizophrenia and depression, Nat. Rev. Neurosci., 17, 524, 10.1038/nrn.2016.57 Hadley, 2014, Ventral tegmental area/midbrain functional connectivity and response to antipsychotic medication in schizophrenia, Neuropsychopharmacology, 39, 1020, 10.1038/npp.2013.305 Howes, 2014, A neurobiological hypothesis for the classification of schizophrenia: type a (hyperdopaminergic) and type B (normodopaminergic), Br. J. Psychiatry, 205, 1, 10.1192/bjp.bp.113.138578 Howes, 2009, Elevated striatal dopamine function linked to prodromal Signs of schizophrenia, Arch. Gen. Psychiatr., 66, 13, 10.1001/archgenpsychiatry.2008.514 Kay, 1987, The positive and negative Syndrome Scale for schizophrenia, Schizophr. Bull., 13, 261, 10.1093/schbul/13.2.261 Kegeles, 2010, Increased synaptic dopamine function in associative regions of the striatum in schizophrenia, Arch. Gen. Psychiatr., 67, 231, 10.1001/archgenpsychiatry.2010.10 Kelly, 2009, L-dopa Modulates functional connectivity in striatal cognitive and motor networks: a double-blind placebo-controlled study, J. Neurosci., 29, 7364, 10.1523/JNEUROSCI.0810-09.2009 Kraguljac, 2013, Increased hippocampal glutamate and volumetric Deficits in unmedicated patients with schizophrenia, JAMA Psychiatry, 70, 1294, 10.1001/jamapsychiatry.2013.2437 Lodge, 2011, Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia, Trends Pharmacol. Sci., 32, 507, 10.1016/j.tips.2011.05.001 Lodge, 2007, Aberrant hippocampal regulation of dopamine neuron responsivity in an animal model of schizophrenia, Schizophr. Bull., 33, 407 Martinez, 2003, Imaging human mesolimbic dopamine transmission with positron emission tomography. Part II: amphetamine-induced dopamine release in the functional subdivisions of the striatum, J. Cerebr. Blood Flow Metabol., 23, 285, 10.1097/01.WCB.0000048520.34839.1A Merritt, 2016, Nature of glutamate alterations in schizophrenia, JAMA Psychiatry, 73, 665, 10.1001/jamapsychiatry.2016.0442 Modinos, 2015, Translating the MAM model of psychosis to humans, Trends Neurosci., 38, 129, 10.1016/j.tins.2014.12.005 Murty, 2014, Resting state networks distinguish human ventral tegmental area from substantia nigra, Neuroimage, 100, 580, 10.1016/j.neuroimage.2014.06.047 Neggers, 2008, Enhanced sensitivity with fast three-dimensional blood-oxygen-level-dependent functional MRI: comparison of SENSE-PRESTO and 2D-EPI at 3 T, NMR Biomed., 21, 663, 10.1002/nbm.1235 O'Neill, 2019, Dysconnectivity of large-scale functional networks in early psychosis: a meta-analysis, Schizophr. Bull., 45, 579, 10.1093/schbul/sby094 Pettersson-Yeo, 2011, Dysconnectivity in schizophrenia: where are we now?, Neurosci. Biobehav. Rev., 35, 1110, 10.1016/j.neubiorev.2010.11.004 Rössler, 2018, Schizotypal traits are linked to dopamine-induced striato-cortical decoupling: a randomized double-blind placebo-controlled study, Schizophr. Bull., 45, 846 Sarpal, 2015, Antipsychotic treatment and functional connectivity of the striatum in first-episode schizophrenia, JAMA Psychiatry, 72, 5, 10.1001/jamapsychiatry.2014.1734 Satterthwaite, 2013, An improved framework for confound regression and filtering for control of motion artifact in the preprocessing of resting-state functional connectivity data, Neuroimage, 64, 240, 10.1016/j.neuroimage.2012.08.052 Scheewe, 2012, Effects of exercise therapy on cardiorespiratory fitness in patients with schizophrenia, Med. Sci. Sports Exerc., 44, 1834, 10.1249/MSS.0b013e318258e120 Stephan, 2006, Synaptic plasticity and dysconnection in schizophrenia, Biol. Psychiatr., 59, 929, 10.1016/j.biopsych.2005.10.005 Stephan, 2009, Dysconnection in Schizophrenia: from abnormal synaptic plasticity to failures of self-monitoring, Schizophr. Bull., 35, 509, 10.1093/schbul/sbn176 van den Heuvel, 2014, Brain networks in schizophrenia, Neuropsychol. Rev., 24, 32, 10.1007/s11065-014-9248-7 Whitfield-Gabrieli, 2009, Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia, Proc. Natl. Acad. Sci. U.S.A., 106, 1279, 10.1073/pnas.0809141106 Winton-Brown, 2017, Altered activation and connectivity in a hippocampal-basal ganglia-midbrain circuit during salience processing in subjects at ultra high risk for psychosis, Transl. Psychiatry, 7, 1, 10.1038/tp.2017.174 Winton-Brown, 2014, Dopaminergic basis of salience dysregulation in psychosis, Trends Neurosci., 37, 85, 10.1016/j.tins.2013.11.003