Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age

Journal of Allergy and Clinical Immunology - Tập 128 Số 3 - Trang 646-652.e5 - 2011
Hans Bisgaard1, Nan Li, Klaus Bønnelykke, Bo Chawes, Thomas Skov, Georg Paludan-Müller, Jakob Stokholm, Birgitte Smith, Karen A. Krogfelt
1Copenhagen Prospective Studies on Asthma in Childhood, Health Sciences, University of Copenhagen, Copenhagen University Hospital, Gentofte, Copenhagen, Denmark. [email protected]

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Manichanh, 2006, Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach, Gut, 55, 205, 10.1136/gut.2005.073817

Kalliomaki, 2008, Early differences in fecal microbiota composition in children may predict overweight, Am J Clin Nutr, 87, 534, 10.1093/ajcn/87.3.534

Turnbaugh, 2009, A core gut microbiome in obese and lean twins, Nature, 457, 480, 10.1038/nature07540

Vrieze, 2010, The environment within: how gut microbiota may influence metabolism and body composition, Diabetologia, 53, 606, 10.1007/s00125-010-1662-7

Vaahtovuo, 2008, Fecal microbiota in early rheumatoid arthritis, J Rheumatol, 35, 1500

Martinez, 1999, Role of microbial burden in aetiology of allergy and asthma, Lancet, 354, SII12, 10.1016/S0140-6736(99)90437-3

Strachan, 2000, Family size, infection and atopy: the first decade of the “hygiene hypothesis.”, Thorax, 55, S2, 10.1136/thorax.55.suppl_1.S2

Liu, 2003, Hygiene hypothesis: fact or fiction?, J Allergy Clin Immunol, 111, 471, 10.1067/mai.2003.172

von, 2007, The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies, PLoS Med, 4, e296, 10.1371/journal.pmed.0040296

Bisgaard, 2004, The Copenhagen Prospective Study on Asthma in Childhood (COPSAC): design, rationale, and baseline data from a longitudinal birth cohort study, Ann Allergy Asthma Immunol, 93, 381, 10.1016/S1081-1206(10)61398-1

Bisgaard, 2006, Intermittent inhaled corticosteroids in infants with episodic wheezing, N Engl J Med, 354, 1998, 10.1056/NEJMoa054692

Bisgaard, 2007, Childhood asthma after bacterial colonization of the airway in neonates, N Engl J Med, 357, 1487, 10.1056/NEJMoa052632

Paganelli, 1998, Specific IgE antibodies in the diagnosis of atopic disease. Clinical evaluation of a new in vitro test system, UniCAP, in six European allergy clinics, Allergy, 53, 763, 10.1111/j.1398-9995.1998.tb03972.x

Chawes, 2009, Objective assessments of allergic and nonallergic rhinitis in young children, Allergy, 64, 1547, 10.1111/j.1398-9995.2009.02085.x

Chawes, 2010, Upper and lower airway patency are associated in young children, Chest, 137, 1332, 10.1378/chest.09-2601

Bisgaard, 2011, Endotyping early childhood asthma by quantitative symptom assessment, J Allergy Clin Immunol, 127, 1155, 10.1016/j.jaci.2011.02.007

Halkjaer, 2006, Development of atopic dermatitis during the first 3 years of life: the Copenhagen prospective study on asthma in childhood cohort study in high-risk children, Arch Dermatol, 142, 561, 10.1001/archderm.142.5.561

Nielsen, 2003, Case study of the distribution of mucosa-associated Bifidobacterium species, Lactobacillus species, and other lactic acid bacteria in the human colon, Appl Environ Microbiol, 69, 7545, 10.1128/AEM.69.12.7545-7548.2003

Ovreas, 1997, Distribution of bacterioplankton in meromictic Lake Saelenvannet, as determined by denaturing gradient gel electrophoresis of PCR-amplified gene fragments coding for 16S rRNA, Appl Environ Microbiol, 63, 3367, 10.1128/AEM.63.9.3367-3373.1997

Muyzer, 1998, Application of denaturing gradient gel electrophoresis (DGGE) and temperature gradient gel electrophoresis (TGGE) in microbial ecology, Antonie Van Leeuwenhoek, 73, 127, 10.1023/A:1000669317571

Ege, 2011, Exposure to environmental microorganisms and childhood asthma, N Engl J Med, 364, 701, 10.1056/NEJMoa1007302

Gloor, 2010, Microbiome profiling by Illumina sequencing of combinatorial sequence-tagged PCR products, PLoS One, 5, e15406, 10.1371/journal.pone.0015406

Tannock, 2001, Molecular assessment of intestinal microflora, Am J Clin Nutr, 73, 410S, 10.1093/ajcn/73.2.410s

Palmer, 2007, Development of the human infant intestinal microbiota, PLoS Biol, 5, e177, 10.1371/journal.pbio.0050177

Millar, 1996, Application of 16S rRNA gene PCR to study bowel flora of preterm infants with and without necrotizing enterocolitis, J Clin Microbiol, 34, 2506, 10.1128/JCM.34.10.2506-2510.1996

Guarner, 2003, Gut flora in health and disease, Lancet, 361, 512, 10.1016/S0140-6736(03)12489-0

Holt, 1995, Environmental factors and primary T-cell sensitisation to inhalant allergens in infancy: reappraisal of the role of infections and air pollution, Pediatr Allergy Immunol, 6, 1, 10.1111/j.1399-3038.1995.tb00250.x

Bjorksten, 1994, Risk factors in early childhood for the development of atopic diseases, Allergy, 49, 400, 10.1111/j.1398-9995.1994.tb00831.x

Bisgaard, 2009, Risk analysis of early childhood eczema, J Allergy Clin Immunol, 123, 1355, 10.1016/j.jaci.2009.03.046

Sjogren, 2009, Altered early infant gut microbiota in children developing allergy up to 5 years of age, Clin Exp Allergy, 39, 518, 10.1111/j.1365-2222.2008.03156.x

Stsepetova, 2007, Molecularly assessed shifts of Bifidobacterium ssp. and less diverse microbial communities are characteristic of 5-year-old allergic children, FEMS Immunol Med Microbiol, 51, 260, 10.1111/j.1574-695X.2007.00306.x

Adlerberth, 2007, Gut microbiota and development of atopic eczema in 3 European birth cohorts, J Allergy Clin Immunol, 120, 343, 10.1016/j.jaci.2007.05.018

Penders, 2007, Gut microbiota composition and development of atopic manifestations in infancy: the KOALA Birth Cohort Study, Gut, 56, 661, 10.1136/gut.2006.100164

Kalliomaki, 2001, Distinct patterns of neonatal gut microflora in infants in whom atopy was and was not developing, J Allergy Clin Immunol, 107, 129, 10.1067/mai.2001.111237

Wang, 2008, Reduced diversity in the early fecal microbiota of infants with atopic eczema, J Allergy Clin Immunol, 121, 129, 10.1016/j.jaci.2007.09.011

Forno, 2008, Diversity of the gut microbiota and eczema in early life, Clin Mol Allergy, 6, 11, 10.1186/1476-7961-6-11

Bjorksten, 2001, Allergy development and the intestinal microflora during the first year of life, J Allergy Clin Immunol, 108, 516, 10.1067/mai.2001.118130

Penders, 2006, Molecular fingerprinting of the intestinal microbiota of infants in whom atopic eczema was or was not developing, Clin Exp Allergy, 36, 1602, 10.1111/j.1365-2222.2006.02599.x

Kirjavainen, 2001, Characterizing the composition of intestinal microflora as a prospective treatment target in infant allergic disease, FEMS Immunol Med Microbiol, 32, 1, 10.1111/j.1574-695X.2001.tb00526.x

Gore, 2008, Bifidobacterium pseudocatenulatum is associated with atopic eczema: a nested case-control study investigating the fecal microbiota of infants, J Allergy Clin Immunol, 121, 135, 10.1016/j.jaci.2007.07.061

Murray, 2005, Fecal microbiota in sensitized wheezy and non-sensitized non-wheezy children: a nested case-control study, Clin Exp Allergy, 35, 741, 10.1111/j.1365-2222.2005.02259.x

Watanabe, 2003, Differences in fecal microflora between patients with atopic dermatitis and healthy control subjects, J Allergy Clin Immunol, 111, 587, 10.1067/mai.2003.105

Dicksved, 2007, Molecular fingerprinting of the fecal microbiota of children raised according to different lifestyles, Appl Environ Microbiol, 73, 2284, 10.1128/AEM.02223-06

Hilty, 2010, Disordered microbial communities in asthmatic airways, PLoS One, 5, e8578, 10.1371/journal.pone.0008578

Moffatt, 2010, A large-scale, consortium-based genomewide association study of asthma, N Engl J Med, 363, 1211, 10.1056/NEJMoa0906312