Redox status expressed as GSH:GSSG ratio as a marker for oxidative stress in paediatric tumour patients

Lochman, 2003, High-throughput capillary electrophoretic method for determination of total aminothiols in plasma and urine, Electrophoresis, 24, 1200, 10.1002/elps.200390154

Michelet, 1995, Blood and plasma glutathione measured in healthy-subjects by HPLC: relation to sex, aging, biological variables, and life habits, Clin Chem, 41, 1509, 10.1093/clinchem/41.10.1509

Pastore, 1998, Fully automated assay for total homocysteine, cysteine, cysteinylglycine, glutathione, cysteamine, and 2-mercaptopropionylglycine in plasma and urine, Clin Chem, 44, 825, 10.1093/clinchem/44.4.825

Richie, 1996, Blood glutathione concentrations in a large-scale human study, Clin Chem, 42, 64, 10.1093/clinchem/42.1.64

Shea, 1984, High-performance liquid chromatographic measurement of exogenous thiosulfate in urine and plasma, Anal Biochem, 140, 589, 10.1016/0003-2697(84)90211-2

Meister, 1976, Glutathione and related gamma-glutamyl compounds: biosynthesis and utilization, Annu Rev Biochem, 45, 559, 10.1146/annurev.bi.45.070176.003015

Griffith, 1979, Potent and specific-inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine), J Biol Chem, 254, 7558, 10.1016/S0021-9258(18)35980-5

Meister, 1986, Intracellular cysteine and glutathione delivery systems, J Am Coll Nutr, 5, 137, 10.1080/07315724.1986.10720121

Carelli, 1997, Cysteine and glutathione secretion in response to protein disulfide bond formation in the ER, Science, 277, 1681, 10.1126/science.277.5332.1681

Locigno, 2001, Reduced glutathione system: role in cancer development, prevention and treatment (review), Int J Oncol, 19, 221

Noctor, 1998, Ascorbate and glutathione: keeping active oxygen under control, Annu Rev Plant Physiol Mol Biol, 49, 249, 10.1146/annurev.arplant.49.1.249

Townsend, 2003, The importance of glutathione in human disease, Biomed Pharmacother, 57, 145, 10.1016/S0753-3322(03)00043-X

Chai, 1994, S-thiolation of individual human neutrophil proteins including actin by stimulation of the respiratory burst: evidence against a role for glutathione disulfide, Arch Biochem Biophys, 310, 273, 10.1006/abbi.1994.1167

Arranz, 2008, The glutathione precursor N-acetylcysteine improves immune function in postmenopausal women, Free Radic Biol Med, 45, 1252, 10.1016/j.freeradbiomed.2008.07.014

Hashimoto, 2008, Effect of glutathione (GSH) depletion on DNA damage and blood chemistry in aged and young rats, J Toxicol Sci, 33, 421, 10.2131/jts.33.421

Christon, 1995, Dietary polyunsaturated fatty acids and aging modulate glutathione-related antioxidants in rat liver, J Nutr, 125, 3062

Maher, 2005, The effects of stress and aging on glutathione metabolism, Ageing Res Rev, 4, 288, 10.1016/j.arr.2005.02.005

Rebrin, 2004, Free aminothiols, glutathione redox state and protein mixed disulphides in aging Drosophila melanogaster, Biochem J, 382, 131, 10.1042/BJ20040506

Rebrin, 2008, Pro-oxidant shift in glutathione redox state during aging, Adv Drug Deliv Rev, 60, 1545, 10.1016/j.addr.2008.06.001

Samiec, 1998, Glutathione in human plasma: decline in association with aging, age-related macular degeneration, and diabetes, Free Radic Biol Med, 24, 699, 10.1016/S0891-5849(97)00286-4

Cerielo, 1997, Hyperglycemia counterbalances the antihypertensive effect of glutathione in diabetic patients: evidence linking hypertension and glycemia through the oxidative stress in diabetes mellitus, J Diabetes Complications, 11, 250, 10.1016/S1056-8727(97)00021-4

Dincer, 2002, Effect of oxidative stress on glutathione pathway in red blood cells from patients with insulin-dependent diabetes mellitus, Metabolism, 51, 1360, 10.1053/meta.2002.35192

Yoshida, 1995, Weakened cellular scavenging activity against oxidative stress in diabetes mellitus: regulation of glutathione synthesis and efflux, Diabetologia, 38, 201, 10.1007/BF00400095

Margutti, 2008, Autoantibodies to the C-terminal subunit of RLIP76 induce oxidative stress and endothelial cell apoptosis in immune-mediated vascular diseases and atherosclerosis, Blood, 111, 4559, 10.1182/blood-2007-05-092825

Signorelli, 2001, Oxidative stress and endothelial damage in patients with asymptomatic carotid atherosclerosis, Clin Exp Med, 1, 9, 10.1007/s10238-001-8002-7

Hassan, 2001, The glutathione defense system in the pathogenesis of rheumatoid arthritis, J Appl Toxicol, 21, 69, 10.1002/jat.736

Pedersen-Lane, 2007, Analysis of the thiol status of peripheral blood leukocytes in rheumatoid arthritis patients, J Leukoc Biol, 81, 934, 10.1189/jlb.0806533

Seven, 2008, Lipid, protein, DNA oxidation and antioxidant status in rheumatoid arthritis, Clin Biochem, 41, 538, 10.1016/j.clinbiochem.2008.01.029

Karelson, 2002, Possible signaling by glutathione and its novel analogue through potent stimulation of frontocortical G proteins in normal aging and in Alzheimer’s disease, Cell Signaling, Transcription, and Translation as Therapeutic Targets, 537

Liu, 2004, Glutathione metabolism during aging and in Alzheimer disease, Strategies for Engineered Negligible Senescence: Why Genuine Control of Aging May Be Foreseeable, 346

Resende, 2008, Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease, Free Radic Biol Med, 44, 2051, 10.1016/j.freeradbiomed.2008.03.012

Lang, 2007, The progression of Parkinson disease: a hypothesis, Neurology, 68, 948, 10.1212/01.wnl.0000257110.91041.5d

Spina, 1989, Dopamine turnover and glutathione oxidation: implications for Parkinson disease, Proc Natl Acad Sci USA, 86, 1398, 10.1073/pnas.86.4.1398

Yamamoto, 2007, Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: relevance to Parkinson disease, J Biol Chem, 282, 4364, 10.1074/jbc.M603712200

Barranco, 2000, Relationship between colorectal cancer glutathione levels and patient survival: early results, Dis Colon Rectum, 43, 1133, 10.1007/BF02236562

Kigawa, 1998, Glutathione concentration may be a useful predictor of response to second-line chemotherapy in patients with ovarian cancer, Cancer, 82, 697, 10.1002/(SICI)1097-0142(19980215)82:4<697::AID-CNCR12>3.0.CO;2-T

Kumar, 1995, Decreased plasma glutathione in cancer of the uterine cervix, Cancer Lett, 94, 107, 10.1016/0304-3835(95)03832-H

Wong, 1994, Glutathione concentration in oral cancer tissues, Cancer Lett, 81, 111, 10.1016/0304-3835(94)90191-0

Yeh, 2006, A study of glutathione status in the blood and tissues of patients with breast cancer, Cell Biochem Funct, 24, 555, 10.1002/cbf.1275

Droge, 2002, Free radicals in the physiological control of cell function, Physiol Rev, 82, 47, 10.1152/physrev.00018.2001

Hayes, 1995, The glutathione S-Transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance, Crit Rev Biochem Mol Biol, 30, 445, 10.3109/10409239509083491

Valko, 2006, Free radicals, metals and antioxidants in oxidative stress-induced cancer, Chem Biol Interact, 160, 1, 10.1016/j.cbi.2005.12.009

Hayes, 1999, Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress, Free Radic Res, 31, 273, 10.1080/10715769900300851

Dalle-Donne, 2006, Biomarkers of oxidative damage in human disease, Clin Chem, 52, 601, 10.1373/clinchem.2005.061408

Klejdus, 2004, Sub-picomole high-performance liquid chromatographic/mass spectrometric determination of glutathione in the maize (Zea mays L.) kernels exposed to cadmium, Anal Chim Acta, 520, 117, 10.1016/j.aca.2004.02.060

Potesil, 2005, Simultaneous femtomole determination of cysteine, reduced and oxidized glutathione, and phytochelatin in maize (Zea mays L.) kernels using high-performance liquid chromatography with electrochemical detection, J Chromatogr A, 1084, 134, 10.1016/j.chroma.2005.06.019

Petrlova, 2006, Simultaneous determination of eight biologically active thiol compounds using gradient elution-liquid chromatography with Coul-Array detection, J Sep Sci, 29, 1166, 10.1002/jssc.200500425

Zitka, 2007, An investigation of glutathione-platinum(II) interactions by means of the flow injection analysis using glassy carbon electrode, Sensors, 7, 1256, 10.3390/s7071256

Iwasaki, 2009, Chromatographic and mass spectrometric analysis of glutathione in biological samples, J Chromatogr B Analyt Biomed Life Sci, 877, 3309, 10.1016/j.jchromb.2009.07.001

Causon, 1997, Validation of chromatographic methods in biomedical analysis - viewpoint and discussion, J Chromatogr B, 689, 175, 10.1016/S0378-4347(96)00297-6