Redefining the In Vivo Origin of Metanephric Nephron Progenitors Enables Generation of Complex Kidney Structures from Pluripotent Stem Cells

Cell Stem Cell - Tập 14 Số 1 - Trang 53-67 - 2014
Atsuhiro Taguchi1, Yusuke Kaku1, Tomoko Ohmori1, Sazia Sharmin1, Minetaro Ogawa2,3, Hiroshi Sasaki4, Ryuichi Nishinakamura1,3
1Department of Kidney Development, Institute of Molecular Embryology and Genetics, Kumamoto University, 2-2-1 Honjo, Kumamoto 860-0811, Japan
2Department of Cell Differentiation, Institute of Molecular Embryology and Genetics, Kumamoto University, 2-2-1 Honjo, Kumamoto 860-0811, Japan
3Japan Science and Technology Agency, CREST, 2-2-1 Honjo, Kumamoto 860-0811, Japan
4Department of Cell Fate Control, Institute of Molecular Embryology and Genetics, Kumamoto University, 2-2-1 Honjo, Kumamoto 860-0811, Japan

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Atsuta, 2013, Transgenesis of the Wolffian duct visualizes dynamic behavior of cells undergoing tubulogenesis in vivo, Dev. Growth Differ., 55, 579, 10.1111/dgd.12047

Attia, 2012, Analysis of nephric duct specification in the avian embryo, Development, 139, 4143, 10.1242/dev.085258

Aulehla, 2010, Signaling gradients during paraxial mesoderm development, Cold Spring Harb. Perspect. Biol., 2, a000869, 10.1101/cshperspect.a000869

Barak, 2012, FGF9 and FGF20 maintain the stemness of nephron progenitors in mice and man, Dev. Cell, 22, 1191, 10.1016/j.devcel.2012.04.018

Bernardo, 2011, BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages, Cell Stem Cell, 9, 144, 10.1016/j.stem.2011.06.015

Bollig, 2009, A highly conserved retinoic acid responsive element controls wt1a expression in the zebrafish pronephros, Development, 136, 2883, 10.1242/dev.031773

Bouchard, 2002, Nephric lineage specification by Pax2 and Pax8, Genes Dev., 16, 2958, 10.1101/gad.240102

Burridge, 2012, Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming, Cell Stem Cell, 10, 16, 10.1016/j.stem.2011.12.013

Costantini, 2010, Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development, Dev. Cell, 18, 698, 10.1016/j.devcel.2010.04.008

Eremina, 2003, Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases, J. Clin. Invest., 111, 707, 10.1172/JCI17423

Fleming, 2013, A role for Vg1/Nodal signaling in specification of the intermediate mesoderm, Development, 140, 1819, 10.1242/dev.093740

Gadue, 2006, Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells, Proc. Natl. Acad. Sci. USA, 103, 16806, 10.1073/pnas.0603916103

Hatini, 1996, Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of Winged Helix transcription factor BF-2, Genes Dev., 10, 1467, 10.1101/gad.10.12.1467

Herrmann, 1990, Cloning of the T gene required in mesoderm formation in the mouse, Nature, 343, 617, 10.1038/343617a0

Humphreys, 2010, Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis, Am. J. Pathol., 176, 85, 10.2353/ajpath.2010.090517

Imuta, 2013, Generation of knock-in mice that express nuclear enhanced green fluorescent protein and tamoxifen-inducible Cre recombinase in the notochord from Foxa2 and T loci, Genesis, 51, 210, 10.1002/dvg.22376

James, 2006, Odd-skipped related 1 is required for development of the metanephric kidney and regulates formation and differentiation of kidney precursor cells, Development, 133, 2995, 10.1242/dev.02442

Kattman, 2011, Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines, Cell Stem Cell, 8, 228, 10.1016/j.stem.2010.12.008

Kim, 2005, Nephrogenic factors promote differentiation of mouse embryonic stem cells into renal epithelia, J. Am. Soc. Nephrol., 16, 3527, 10.1681/ASN.2005050544

Kispert, 1998, Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney, Development, 125, 4225, 10.1242/dev.125.21.4225

Kobayashi, 2008, Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development, Cell Stem Cell, 3, 169, 10.1016/j.stem.2008.05.020

Lengerke, 2008, BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway, Cell Stem Cell, 2, 72, 10.1016/j.stem.2007.10.022

Li, 2000, PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor, Nat. Cell Biol., 2, 302, 10.1038/35010579

Madisen, 2010, A robust and high-throughput Cre reporting and characterization system for the whole mouse brain, Nat. Neurosci., 13, 133, 10.1038/nn.2467

Mae, 2013, Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells, Nat. Commun., 4, 1367, 10.1038/ncomms2378

Mendelsohn, 1999, Stromal cells mediate retinoid-dependent functions essential for renal development, Development, 126, 1139, 10.1242/dev.126.6.1139

Moriya, 1993, Induction of pronephric tubules by activin and retinoic acid in presumptive ectoderm of Xenopus laevis, Dev. Growth Differ., 35, 123, 10.1111/j.1440-169X.1993.00123.x

Mugford, 2008, Hoxd11 specifies a program of metanephric kidney development within the intermediate mesoderm of the mouse embryo, Dev. Biol., 319, 396, 10.1016/j.ydbio.2008.03.044

Mugford, 2008, Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney, Dev. Biol., 324, 88, 10.1016/j.ydbio.2008.09.010

Müller, 1997, Integrin alpha8beta1 is critically important for epithelial-mesenchymal interactions during kidney morphogenesis, Cell, 88, 603, 10.1016/S0092-8674(00)81903-0

Murry, 2008, Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development, Cell, 132, 661, 10.1016/j.cell.2008.02.008

Narayanan, 2013, Human embryonic stem cells differentiate into functional renal proximal tubular-like cells, Kidney Int., 83, 593, 10.1038/ki.2012.442

Nelson, 2008, Generation and expression of a Hoxa11eGFP targeted allele in mice, Dev. Dyn., 237, 3410, 10.1002/dvdy.21756

Nishinakamura, 2001, Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development, Development, 128, 3105, 10.1242/dev.128.16.3105

Obara-Ishihara, 1999, The surface ectoderm is essential for nephric duct formation in intermediate mesoderm, Development, 126, 1103, 10.1242/dev.126.6.1103

Osafune, 2006, Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay, Development, 133, 151, 10.1242/dev.02174

Poladia, 2006, Role of fibroblast growth factor receptors 1 and 2 in the metanephric mesenchyme, Dev. Biol., 291, 325, 10.1016/j.ydbio.2005.12.034

Saxen, 1987

Schnabel, 2003, Pbx1 regulates nephrogenesis and ureteric branching in the developing kidney, Dev. Biol., 254, 262, 10.1016/S0012-1606(02)00038-6

Takahashi, 2007, Induction of pluripotent stem cells from adult human fibroblasts by defined factors, Cell, 131, 861, 10.1016/j.cell.2007.11.019

Takahashi, 2001, Temporally compartmentalized expression of ephrin-B2 during renal glomerular development, J. Am. Soc. Nephrol., 12, 2673, 10.1681/ASN.V12122673

Takemoto, 2011, Tbx6-dependent Sox2 regulation determines neural or mesodermal fate in axial stem cells, Nature, 470, 394, 10.1038/nature09729

Tam, 1997, Mouse gastrulation: the formation of a mammalian body plan, Mech. Dev., 68, 3, 10.1016/S0925-4773(97)00123-8

Tzouanacou, 2009, Redefining the progression of lineage segregations during mammalian embryogenesis by clonal analysis, Dev. Cell, 17, 365, 10.1016/j.devcel.2009.08.002

Watanabe, 2007, A ROCK inhibitor permits survival of dissociated human embryonic stem cells, Nat. Biotechnol., 25, 681, 10.1038/nbt1310

Wellik, 2002, Hox11 paralogous genes are essential for metanephric kidney induction, Genes Dev., 16, 1423, 10.1101/gad.993302

Williams, 2012, SnapShot: directed differentiation of pluripotent stem cells, Cell, 149, 1174, 10.1016/j.cell.2012.05.015

Wilson, 2009, Stem cells, signals and vertebrate body axis extension, Development, 136, 1591, 10.1242/dev.021246

Yamaguchi, 1999, T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification, Genes Dev., 13, 3185, 10.1101/gad.13.24.3185

Zhou, 2008, Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart, Nature, 454, 109, 10.1038/nature07060