Recombination-dependent replication: new perspectives from site-specific fork barriers

Current Opinion in Genetics & Development - Tập 71 - Trang 129-135 - 2021
Antony Carr1, Sarah Lambert2,3,4
1Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Falmer, Sussex, BN1 9RQ, UK
2Institut Curie, Université PSL, CNRS UMR3348, INSERM U1278, 91400 Orsay, France
3Université Paris-Saclay, CNRS UMR3348, INSERM U1278, 91400 Orsay, France
4Equipe Labélisée Ligue Nationale Contre Le Cancer, 91400 Orsay, France

Tài liệu tham khảo

Nachman, 2000, Estimate of the mutation rate per nucleotide in humans, Genetics, 156, 297, 10.1093/genetics/156.1.297 Blokzijl, 2016, Tissue-specific mutation accumulation in human adult stem cells during life, Nature, 538, 260, 10.1038/nature19768 Xue, 2009, Human Y chromosome base-substitution mutation rate measured by direct sequencing in a deep-rooting pedigree, Curr Biol, 19, 1453, 10.1016/j.cub.2009.07.032 Schumacher, 2021, The central role of DNA damage in the ageing process, Nature, 592, 695, 10.1038/s41586-021-03307-7 Bakhoum, 2018, Chromosomal instability drives metastasis through a cytosolic DNA response, Nature, 553, 467, 10.1038/nature25432 Dahiya, 2021, Mechanistic origins of diverse genome rearrangements in cancer, Semin Cell Dev Biol Glover, 2017, Fragile sites in cancer: more than meets the eye, Nat Rev Cancer, 17, 489, 10.1038/nrc.2017.52 Mocanu, 2021, G2 DNA synthesis is essential to safeguard chromosome integrity under replication stress, Sneak Peak Murakami, 2002, Maintenance of replication forks and the S-phase checkpoint by Cdc18p and Orp1p, Nat Cell Biol, 4, 384, 10.1038/ncb789 Mocanu, 2021, Mind the replication gap, R Soc Open Sci, 8, 10.1098/rsos.201932 Bhowmick, 2016, RAD52 facilitates mitotic DNA synthesis following replication stress, Mol Cell, 64, 1117, 10.1016/j.molcel.2016.10.037 Minocherhomji, 2015, Replication stress activates DNA repair synthesis in mitosis, Nature, 528, 286, 10.1038/nature16139 Schlacher, 2011, Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11, Cell, 145, 529, 10.1016/j.cell.2011.03.041 Costes, 2012, Homologous recombination as a replication fork escort: fork-protection and recovery, Biomolecules, 3, 39, 10.3390/biom3010039 Kolinjivadi, 2017, Moonlighting at replication forks - a new life for homologous recombination proteins BRCA1, BRCA2 and RAD51, FEBS Lett, 591, 1083, 10.1002/1873-3468.12556 Petermann, 2010, Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair, Mol Cell, 37, 492, 10.1016/j.molcel.2010.01.021 Ait Saada, 2018, Preserving replication fork integrity and competence via the homologous recombination pathway, DNA Repair (Amst), 71, 135, 10.1016/j.dnarep.2018.08.017 Malkova, 2013, Break-induced replication: functions and molecular mechanism, Curr Opin Genet Dev, 23, 271, 10.1016/j.gde.2013.05.007 Sakofsky, 2017, Break induced replication in eukaryotes: mechanisms, functions, and consequences, Crit Rev Biochem Mol Biol, 52, 395, 10.1080/10409238.2017.1314444 Berti, 2016, Replication stress: getting back on track, Nat Struct Mol Biol, 23, 103, 10.1038/nsmb.3163 Quinet, 2021, To skip or not to skip: choosing repriming to tolerate DNA damage, Mol Cell, 81, 649, 10.1016/j.molcel.2021.01.012 Osia, 2021, Investigation of Break-Induced Replication in Yeast, Methods Mol Biol, 2153, 307, 10.1007/978-1-0716-0644-5_22 Mayle, 2015, DNA REPAIR. Mus81 and converging forks limit the mutagenicity of replication fork breakage, Science, 349, 742, 10.1126/science.aaa8391 Larsen, 2014, Tus-Ter as a tool to study site-specific DNA replication perturbation in eukaryotes, Cell Cycle, 13, 2994, 10.4161/15384101.2014.958912 Larsen, 2014, The Escherichia coli Tus-Ter replication fork barrier causes site-specific DNA replication perturbation in yeast, Nat Commun, 5, 10.1038/ncomms4574 Willis, 2014, BRCA1 controls homologous recombination at Tus/Ter-stalled mammalian replication forks, Nature, 510, 556, 10.1038/nature13295 Calzada, 2005, Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork, Genes Dev, 19, 1905, 10.1101/gad.337205 Mizuno, 2013, Recombination-restarted replication makes inverted chromosome fusions at inverted repeats, Nature, 493, 246, 10.1038/nature11676 Jacome, 2011, Lac operator repeats generate a traceable fragile site in mammalian cells, EMBO Rep, 12, 1032, 10.1038/embor.2011.158 Beuzer, 2014, Establishment of a replication fork barrier following induction of DNA binding in mammalian cells, Cell Cycle, 13, 1607, 10.4161/cc.28627 Sofueva, 2011, Ultrafine anaphase bridges, broken DNA and illegitimate recombination induced by a replication fork barrier, Nucleic Acids Res, 39, 6568, 10.1093/nar/gkr340 Polleys, 2020, Genetic assays to study repeat fragility in Saccharomyces cerevisiae, Methods Mol Biol, 2056, 83, 10.1007/978-1-4939-9784-8_5 Lambert, 2005, Gross chromosomal rearrangements and elevated recombination at an inducible site-specific replication fork barrier, Cell, 121, 689, 10.1016/j.cell.2005.03.022 Ahn, 2005, Replication fork blockage by RTS1 at an ectopic site promotes recombination in fission yeast, EMBO J, 24, 2011, 10.1038/sj.emboj.7600670 Liu, 2021, Tracking break-induced replication shows that it stalls at roadblocks, Nature, 590, 655, 10.1038/s41586-020-03172-w Donnianni, 2019, DNA polymerase delta synthesizes both strands during break-induced replication, Mol Cell, 76, 371, 10.1016/j.molcel.2019.07.033 Jalan, 2019, Factors affecting template switch recombination associated with restarted DNA replication, eLife, 8, 10.7554/eLife.41697 Tamang, 2019, The PCNA unloader Elg1 promotes recombination at collapsed replication forks in fission yeast, eLife, 8, 10.7554/eLife.47277 Wong, 2019, The Fml1-MHF complex suppresses inter-fork strand annealing in fission yeast, eLife, 8, 10.7554/eLife.49784 Teixeira-Silva, 2017, The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks, Nat Commun, 8, 10.1038/s41467-017-02144-5 Larsen, 2017, Stalled replication forks generate a distinct mutational signature in yeast, Proc Natl Acad Sci U S A, 114, 9665, 10.1073/pnas.1706640114 Daigaku, 2015, A global profile of replicative polymerase usage, Nat Struct Mol Biol, 22, 192, 10.1038/nsmb.2962 Naiman, 2021, Replication dynamics of recombination-dependent replication forks, Nat Commun, 12, 923, 10.1038/s41467-021-21198-0 Hauer, 2017, Chromatin and nucleosome dynamics in DNA damage and repair, Genes Dev, 31, 2204, 10.1101/gad.307702.117 Mitrentsi, 2020, How to maintain the genome in nuclear space, Curr Opin Cell Biol, 64, 58, 10.1016/j.ceb.2020.02.014 Su, 2015, Regulation of recombination at yeast nuclear pores controls repair and triplet repeat stability, Genes Dev, 29, 1006, 10.1101/gad.256404.114 Whalen, 2020, Relocation of collapsed forks to the nuclear pore complex depends on sumoylation of DNA repair proteins and permits Rad51 association, Cell Rep, 31, 10.1016/j.celrep.2020.107635 Kramarz, 2020, The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal, Nat Commun, 11, 10.1038/s41467-020-19516-z Miyabe, 2015, Polymerase δ replicates both strands after homologous recombination-dependent fork restart, Nat Struct Mol Biol, 22, 932, 10.1038/nsmb.3100 Nguyen, 2015, Recombination occurs within minutes of replication blockage by RTS1 producing restarted forks that are prone to collapse, eLife, 4, 10.7554/eLife.04539 Jørgensen, 2019, Esc2 promotes telomere stability in response to DNA replication stress, Nucleic Acids Res, 47, 4597, 10.1093/nar/gkz158 Matmati, 2020, Telomerase repairs collapsed replication forks at telomeres, Cell Rep, 30, 3312, 10.1016/j.celrep.2020.02.065 Aguilera, 2020, The nuclear pore complex prevents sister chromatid recombination during replicative senescence, Nat Commun, 11, 160, 10.1038/s41467-019-13979-5 Willis, 2017, Mechanism of tandem duplication formation in BRCA1-mutant cells, Nature, 551, 590, 10.1038/nature24477 Panday, 2021, FANCM regulates repair pathway choice at stalled replication forks, Mol Cell, 81, 2428, 10.1016/j.molcel.2021.03.044 Lamm, 2020, Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress, Nat Cell Biol, 22, 1460, 10.1038/s41556-020-00605-6