Recombinant antibody libraries and selection technologies

Smith, 1985, Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface, Science, 228, 1315, 10.1126/science.4001944 Parmley, 1988, Antibody-selectable filamentous fd phage vectors: affinity purification of target genes, Gene, 73, 305, 10.1016/0378-1119(88)90495-7 Barbas, 1991, Assembly of combinatorial antibody libraries on phage surfaces: the gene III site, Proc. Natl. Acad. Sci. U.S.A., 88, 7978, 10.1073/pnas.88.18.7978 Breitling, 1991, A surface expression vector for antibody screening, Gene, 104, 147, 10.1016/0378-1119(91)90244-6 Clackson, 1991, Making antibody fragments using phage display libraries, Nature, 352, 624, 10.1038/352624a0 Hoogenboom, 1991, Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains, Nucleic Acids Res., 19, 4133, 10.1093/nar/19.15.4133 Kang, 1991, Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces, Proc. Natl. Acad. Sci. U.S.A., 88, 4363, 10.1073/pnas.88.10.4363 Marks, 1991, Bypassing immunization. Human antibodies from V-gene libraries displayed on phage, J. Mol. Biol., 222, 581, 10.1016/0022-2836(91)90498-U McCafferty, 1990, Phage antibodies: filamentous phage displaying antibody variable domains, Nature, 348, 552, 10.1038/348552a0 de Haard, 1999, A large nonimmunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies, J. Biol. Chem., 274, 18218, 10.1074/jbc.274.26.18218 Glanville, 2009, Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire, Proc. Natl. Acad. Sci. U.S.A., 106, 20216, 10.1073/pnas.0909775106 Pelat, 2007, High-affinity, human antibody-like antibody fragment (single-chain variable fragment) neutralizing the lethal factor (LF) of Bacillus anthracis by inhibiting protective antigen-LF complex formation, Antimicrob. Agents Chemother., 51, 2758, 10.1128/AAC.01528-06 Pelat, 2009, Non-human primate immune libraries combined with germline humanization, MAbs, 1, 377, 10.4161/mabs.1.4.8635 Barbas, 1992, Semisynthetic combinatorial antibody libraries: a chemical solution to the diversity problem, Proc. Natl. Acad. Sci. U.S.A., 89, 4457, 10.1073/pnas.89.10.4457 de Kruif, 1995, Selection and application of human single chain Fv antibody fragments from a semi-synthetic phage antibody display library with designed CDR3 regions, J. Mol. Biol., 248, 97, 10.1006/jmbi.1995.0204 Pini, 1998, Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel, J. Biol. Chem., 273, 21769, 10.1074/jbc.273.34.21769 Hoet, 2005, Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity, Nat. Biotechnol., 23, 344, 10.1038/nbt1067 Knappik, 2000, Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides, J. Mol. Biol., 296, 57, 10.1006/jmbi.1999.3444 Nahary, L. and Benhar, I. (2009) Design of a human synthetic combinatorial library of single-chain antibodies. In Therapeutic Antibodies: Methods and Protocols, (vol. 525) (Dmitrov ed), Methods Mol. Biol., Springer. pp. 61–80 Cobaugh, 2008, Synthetic antibody libraries focused towards peptide ligands, J. Mol. Biol., 378, 622, 10.1016/j.jmb.2008.02.037 Gao, 1999, Making artificial antibodies: a format for phage display of combinatorial heterodimeric arrays, Proc. Natl. Acad. Sci. U.S.A., 96, 6025, 10.1073/pnas.96.11.6025 Harvey, 2004, Anchored periplasmic expression, a versatile technology for the isolation of high-affinity antibodies from Escherichia coli-expressed libraries, Proc. Natl. Acad. Sci. U.S.A., 101, 9193, 10.1073/pnas.0400187101 Mazor, 2007, Isolation of engineered, full-length antibodies from libraries expressed in Escherichia coli, Nat. Biotechnol., 25, 563, 10.1038/nbt1296 Boder, 2000, Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity, Proc. Natl. Acad. Sci. U.S.A., 97, 10701, 10.1073/pnas.170297297 Feldhaus, 2004, Yeast display of antibody fragments: a discovery and characterization platform, J. Immunol. Methods, 290, 69, 10.1016/j.jim.2004.04.009 Ho, 2006, Isolation of anti-CD22 Fv with high affinity by Fv display on human cells, Proc. Natl. Acad. Sci. U.S.A., 103, 9637, 10.1073/pnas.0603653103 Ho, 2009, Display and selection of scFv antibodies on HEK-293T cells, Methods Mol. Biol., 562, 99, 10.1007/978-1-60327-302-2_8 Hanes, 2000, Picomolar affinity antibodies from a fully synthetic naive library selected and evolved by ribosome display, Nat. Biotechnol., 18, 1287, 10.1038/82407 Fukuda, 2006, Nucleic Acids Res., 34, e127, 10.1093/nar/gkl618 de Wildt, 2000, Antibody arrays for high-throughput screening of antibody–antigen interactions, Nat. Biotechnol., 18, 989, 10.1038/79494 Bowley, 2009, Libraries against libraries for combinatorial selection of replicating antigen–antibody pairs, Proc. Natl. Acad. Sci. U.S.A., 106, 1380, 10.1073/pnas.0812291106 2009