Recent advances on chitosan-based micro- and nanoparticles in drug delivery

Journal of Controlled Release - Tập 100 Số 1 - Trang 5-28 - 2004
Sunil A. Agnihotri1, Mallikarjuna N. Nadagouda1, Tejraj M. Aminabhavi1
1Drug Delivery Division, Center of Excellence in Polymer Science, Karnatak University, Dharwad 580 003, India

Tóm tắt

Từ khóa


Tài liệu tham khảo

Berscht, 1994, Incorporation of basic fibroblast growth factor into methylpyrrolidinone chitosan fleeces and determination of the in vitro release characteristics, Biomaterials, 15, 593, 10.1016/0142-9612(94)90209-7

Illum, 1998, Chitosan and its use as a pharmaceutical excipient, Pharm. Res., 15, 1326, 10.1023/A:1011929016601

Dodane, 1998, Pharmaceutical applications of chitosan, Pharm. Sci. Technol. Today, 1, 246, 10.1016/S1461-5347(98)00059-5

Felt, 1998, Chitosan: a unique polysaccharide for drug delivery, Drug Dev. Ind. Pharm., 24, 979, 10.3109/03639049809089942

Yao, 1995, Microcapsules/microspheres related to chitosan, J. Macromol. Sci., Rev. Macromol. Chem. Phys., C35, 155, 10.1080/15321799508014592

Kas, 1997, Chitosan: properties, preparations and application to microparticulate systems, J. Microencapsulation, 14, 689, 10.3109/02652049709006820

Muzzarelli, 1986

Sjak-Braek, 1992

Sannan, 1976, Studies on chitin, 2. Effect of deacetylation on solubility, Makromol. Chem., 177, 3589, 10.1002/macp.1976.021771210

Nicol, 1991, Life after death for empty shells, New Sci., 129, 46

Arai, 1968, Toxicity of chitosan, Bull. Tokai Reg. Fish Lab., 43, 89

Chandy, 1990, Chitosan as a biomaterial, Biomater. Artif. Org., 18, 1, 10.3109/10731199009117286

Hou, 1985, Pharmaceutical application of biomedical polymers. Part XVI. Sustained release of indomethacin from chitosan, Chem. Pharm. Bull., 33, 3986, 10.1248/cpb.33.3986

Miyazaki, 1981, Pharmaceutical application of biomedical polymers. Part IV. The use of chitin and chitosan as drug carriers, Chem. Pharm. Bull., 29, 3067, 10.1248/cpb.29.3067

Handa, 1985, Novel method for the preparation of controlled-release theophylline granules coated with a polyelectrolyte complex of sodium polyphosphate-chitosan, J. Pharm. Sci., 74, 264, 10.1002/jps.2600740308

Miyazaki, 1988, Sustained-release and intragastric-floating granules of indomethacin using chitosan in rabbits, Chem. Pharm. Bull., 36, 4033, 10.1248/cpb.36.4033

Sawayanagi, 1982, Use of chitosan for sustained-release preparations of water-soluble drugs, Chem. Pharm. Bull., 30, 4213, 10.1248/cpb.30.4213

Shiraishi, 1993, Controlled release of indomethacin by chitosan–polyelectrolyte complex: optimization and in vivo/in vitro evaluation, J. Control. Release, 25, 217, 10.1016/0168-3659(93)90080-O

Lehr, 1992, In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers, Int. J. Pharm., 78, 43, 10.1016/0378-5173(92)90353-4

Lueβen, 1994, Bioadhesive polymers for the peroral delivery of peptide drugs, J. Control. Release, 29, 329, 10.1016/0168-3659(94)90078-7

Illum, 1994, Chitosan as a novel nasal delivery system for peptide drugs, Pharm. Res., 11, 1186, 10.1023/A:1018901302450

Imai, 1991, Interaction of indomethacin with low molecular weight chitosan, and improvements of some pharmaceutical properties of indomethacin by low molecular weight chitosans, Int. J. Pharm., 67, 11, 10.1016/0378-5173(91)90260-U

Genta, 1994, Spray-drying for the preparation of chitosan microspheres, Proc. Int. Symp. Control. Release Bioact. Mater., 21, 616

Sawayanagi, 1983, Enhancement of dissolution properties of prednisolone from ground mixtures with chitin or chitosan, Chem. Pharm. Bull., 31, 2507, 10.1248/cpb.31.2507

Gallo, 1988, Receptor-mediated magnetic carriers: basis for targeting, Pharm. Res., 5, 300, 10.1023/A:1015978704810

Hassan, 1992, Optimized formulation of magnetic chitosan microspheres containing the anticancer agent, oxantrazole, Pharm. Res., 9, 390, 10.1023/A:1015803321609

Artursson, 1994, Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (CACO-2), Pharm. Res., 11, 1358, 10.1023/A:1018967116988

Akbuga, 1994, Preparation and evaluation of cross-linked chitosan microspheres containing furosemide, Int. J. Pharm., 111, 217, 10.1016/0378-5173(94)90344-1

Thanoo, 1992, Cross-linked chitosan microspheres: preparation and evaluation as a matrix for the controlled release of pharmaceuticals, J. Pharm. Pharmacol., 44, 283, 10.1111/j.2042-7158.1992.tb03607.x

Soppimath, 2000, Controlled release of antihypertensive drug from the interpenetrating network poly(vinyl alcohol) guar gum hydrogel microspheres, J. Biomater. Sci., Polym. Ed., 11, 27, 10.1163/156856200743472

Soppimath, 2002, Water transport and drug release study of cross-linked guar gum grafted polyacrylamide hydrogel microspheres for the controlled release application, Eur. J. Pharm. Biopharm., 53, 87, 10.1016/S0939-6411(01)00205-3

Kulkarni, 2001, Controlled release of cefadroxil using sodium alginate interpenetrating network with gelatin/egg albumin, Eur. J. Pharm. Biopharm., 51, 127, 10.1016/S0939-6411(00)00150-8

Kumbar, 2002, Cross-linked chitosan microspheres for encapsulation of diclofenac sodium: effect of cross-linking agent, J. Microencapsulation, 19, 173, 10.1080/02652040110065422

Kumbar, 2003, Synthesis and characterization of modified chitosan microspheres: effect of the grafting ratio on the controlled release of nifedipine through microspheres, J. Appl. Polym. Sci., 89, 2940, 10.1002/app.12386

Soppimath, 2001, Biodegradable polymeric nanoparticles as drug delivery devices, J. Control. Release, 70, 1, 10.1016/S0168-3659(00)00339-4

Singh, 2000, Biomedical applications of chitin, chitosan and their derivatives, J. Macromol. Sci., Rev. Macromol. Chem. Phys., C40, 69, 10.1081/MC-100100579

Singla, 2001, Chitosan: some pharmaceutical and biological aspects an update, J. Pharm. Pharmacol., 53, 1047, 10.1211/0022357011776441

Liu, 2002, Chitosan and its derivatives—a promising non-viral vector for gene transfection, J. Control. Release, 83, 1, 10.1016/S0168-3659(02)00144-X

Hejazi, 2003, Chitosan-based gastrointestinal delivery systems, J. Control. Release, 89, 151, 10.1016/S0168-3659(03)00126-3

Sinha, 2004, Chitosan microspheres as a potential carrier for drugs, Int. J. Pharm., 274, 1, 10.1016/j.ijpharm.2003.12.026

Kreuter, 1994, Nanoparticles, 219

Brannon Peppas, 1995, Recent advances on the use of biodegradable microparticles and nanoparticles in the controlled drug delivery, Int. J. Pharm., 116, 1, 10.1016/0378-5173(94)00324-X

Couvreur, 1986

Akbuga, 1994, Preparation and evaluation of cross-linked chitosan microspheres containing furosemide, Int. J. Pharm., 11, 217, 10.1016/0378-5173(94)90344-1

Al-Helw, 1998, Preparation and evaluation of sustained release cross-linked chitosan microspheres containing phenobarbitone, J. Microencapsulation, 15, 373, 10.3109/02652049809006864

Denkbas, 1998, 5-Fluorouracil loaded chitosan microspheres for chemoembolization, J. Microencapsulation, 16, 741

Sankar, 2001, Chitosan based pentazocine microspheres for intranasal systemic delivery: development and biopharmaceutical evaluation, Pharmazie, 56, 223

Jameela, 1998, Progesterone-loaded chitosan microspheres: a long acting biodegradable controlled delivery system, J. Control. Release, 52, 17, 10.1016/S0168-3659(97)00187-9

Bugamelli, 1998, Controlled insulin release from chitosan microparticles, Arch. Pharm., 331, 133, 10.1002/(SICI)1521-4184(199804)331:4<133::AID-ARDP133>3.0.CO;2-H

Nishimura, 1986, Macrophage activation with multiporous beads prepared from partially deacetylated chitin, J. Biomed. Mater. Res., 20, 1359, 10.1002/jbm.820200910

Berthod, 1996, Chitosan microspheres—improved acid stability and change in physicochemical properties by cross-linking, Proc. Int. Symp. Control. Release Bioact. Mater., 23, 369

Ozbas-Turan, 2002, Controlled release of interleukin-2 from chitosan microspheres, J. Pharm. Sci., 91, 124, 10.1002/jps.10122

Mao, 2001, Chitosan DNA nanoparticles as gene delivery carriers: synthesis, characterization and transfection efficiency, J. Control. Release, 70, 399, 10.1016/S0168-3659(00)00361-8

He, 1999, Chitosan microspheres prepared by spray drying, Int. J. Pharm., 187, 53, 10.1016/S0378-5173(99)00125-8

Conti, 1998, Microencapsulation of cetylpyridinium chloride with a bioadhesive polymer, Proc. Int. Symp. Control. Release Bioact. Mater., 25, 822

Ganza-Gonzalez, 1999, Chitosan and chondroitin microspheres for oral-administration controlled release of metoclopramide, Eur. J. Pharm. Biopharm., 48, 149, 10.1016/S0939-6411(99)00040-5

Shi, 2002, Preparation of chitosan/ethylcellulose complex microcapsule and its application in controlled release of vitamin D-2, Biomaterials, 23, 4469, 10.1016/S0142-9612(02)00165-5

C.W. Bishop, J.C. Knutson, C.R. Valliere, Method of treating prostatic disease using delayed and/or sustained release vitamin D formulation, US Pat. 5 795 882, 1998.

Giunchedi, 1998, Preparation and characterization of ampicillin loaded methylpyrrolidinone chitosan and chitosan microspheres, Biomaterials, 19, 157, 10.1016/S0142-9612(97)00181-6

Lorenzo-Lamosa, 1998, Design of microencapsulated chitosan microspheres for colonic drug delivery, J. Control. Release, 52, 109, 10.1016/S0168-3659(97)00203-4

Huang, 2002, Formulation factors in preparing BTM-chitosan microspheres by spray drying method, Int. J. Pharm., 242, 239, 10.1016/S0378-5173(02)00164-3

Tokumitsu, 1999, Chitosan–gadopentetic acid complex nanoparticles for gadolinium neutron capture therapy of cancer: preparation by novel emulsion-droplet coalescence technique and characterization, Pharm. Res., 16, 1830, 10.1023/A:1018995124527

Polk, 1994, Controlled release of albumin from chitosan-alginate microcapsules, J. Pharm. Sci., 83, 178, 10.1002/jps.2600830213

Liu, 1997, Controlled release of interleukin-2 for tumor immunotherapy using alginate:chitosan porous microspheres, J. Control. Release, 43, 65, 10.1016/S0168-3659(96)01471-X

Kawashima, 1985, Novel method for the preparation of controlled-release theophylline granules coated with a polyelectrolyte complex of sodium polyphosphate-chitosan, J. Pharm. Sci., 74, 264, 10.1002/jps.2600740308

Kawashima, 1985, The effect of thickness and hardness of the coating film on the drug release of theophylline granules, Chem. Pharm. Bull., 33, 2469, 10.1248/cpb.33.2469

Bodmeier, 1989, Preparation and evaluation of drug-containing chitosan beads, Drug Dev. Ind. Pharm., 15, 1475, 10.3109/03639048909062758

Shirashi, 1993, Controlled release of indomethacin by chitosan–polyelectrolyte complex: optimization and in vivo: in vitro evaluation, J. Control. Release, 25, 217, 10.1016/0168-3659(93)90080-O

Sezer, 1995, Controlled release of piroxicam from chitosan beads, Int. J. Pharm., 121, 113, 10.1016/0378-5173(94)00413-Y

Aydin, 1996, Chitosan beads for the delivery of salmon calcitonin: preparation and characteristics, Int. J. Pharm., 131, 101, 10.1016/0378-5173(95)04300-4

Calvo, 1997, Chitosan and chitosan: ethylene oxide-propylene oxide block copolymer nanoparticles as novel carriers for protein and vaccines, Pharm. Res., 14, 1431, 10.1023/A:1012128907225

Calvo, 1997, Novel hydrophilic chitosan-polyethylene oxide nanoparticles as protein carriers, J. Appl. Polym. Sci., 63, 125, 10.1002/(SICI)1097-4628(19970103)63:1<125::AID-APP13>3.0.CO;2-4

Shu, 2000, A novel approach to prepare tripolyphosphate/chitosan complex beads for controlled release drug delivery, Int. J. Pharm., 201, 51, 10.1016/S0378-5173(00)00403-8

Fernandez-Urrusuno, 1999, Enhancement of nasal absorption of insulin using chitosan nanoparticles, Pharm. Res., 16, 1576, 10.1023/A:1018908705446

Pan, 2002, Chitosan nanoparticles improve the intestinal absorption of insulin in vivo, Int. J. Pharm., 249, 139, 10.1016/S0378-5173(02)00486-6

Xu, 2003, Effect of molecular structure of chitosan on protein delivery properties of chitosan nanoparticles, Int. J. Pharm., 250, 215, 10.1016/S0378-5173(02)00548-3

Ko, 2002, Preparation and characterization of chitosan microparticles intended for controlled drug delivery, Int. J. Pharm., 249, 165, 10.1016/S0378-5173(02)00487-8

Leong, 1982, Inverse microemulsion polymerization, J. Phys. Chem., 86, 2269, 10.1021/j100210a001

Maitra, 1984, Determination of size parameters of water–Aerosol OT–oil reverse micelles from their nuclear magnetic resonance data, J. Phys. Chem., 88, 5122, 10.1021/j150665a064

Luisi, 1988, Reverse micelles as hosts for proteins and small molecules, Biochim. Biophys. Acta, 947, 209, 10.1016/0304-4157(88)90025-1

Mitra, 2001, Tumor targeted delivery of encapsulated dextran–doxorubicin conjugate using chitosan nanoparticles as carrier, J. Control. Release, 74, 317, 10.1016/S0168-3659(01)00342-X

Agnihotri, 2004, Controlled release of clozapine through chitosan microparticles prepared by a novel method, J. Control. Release, 96, 245, 10.1016/j.jconrel.2004.01.025

Akbuga, 1999, Effect of formulation variables on cis-platin loaded chitosan microsphere properties, J. Microencapsulation, 16, 697, 10.1080/026520499288645

Jameela, 1994, Cross-linked chitosan microspheres as carriers for prolonged delivery of macromolecular drugs, J. Biomater. Sci., Polym. Ed., 6, 621, 10.1163/156856294X00563

Hejazi, 2002, Stomach-specific anti-H. pylori therapy. I: preparation and characterization of tetracyline-loaded chitosan microspheres, Int. J. Pharm., 235, 87, 10.1016/S0378-5173(01)00985-1

Kweon, 1999, Drug-release behavior of chitosan-g-poly(vinyl alcohol) copolymer matrix, J. Appl. Polym. Sci., 74, 458, 10.1002/(SICI)1097-4628(19991010)74:2<458::AID-APP29>3.0.CO;2-6

Higuchi, 1963, Mechanism of sustained action medication, J. Pharm. Sci., 52, 1145, 10.1002/jps.2600521210

Washington, 1990, Drug release from microdisperse systems: a critical review, Int. J. Pharm., 58, 1, 10.1016/0378-5173(90)90280-H

Guy, 1982, Calculations of drug release rates from spherical particles, Int. J. Pharm., 11, 199, 10.1016/0378-5173(82)90038-2

Ritger, 1987, A simple equation for description of solute release. II. Fickian and anomalous release from swellable devices, J. Control. Release, 5, 37, 10.1016/0168-3659(87)90035-6

Peppas, 1987, vol. 3, 103

Orienti, 1996, Indomethacin loaded chitosan microspheres. Correlation between the erosion process and release kinetics, J. Microencapsulation, 13, 463, 10.3109/02652049609026031

Pantaleone, 1991, Advances in chitin and chitosan

Zhang, 2002, An in vitro evaluation of a chitosan-containing multiparticulate system for macromolecule delivery to the colon, Int. J. Pharm., 239, 197, 10.1016/S0378-5173(02)00112-6

Genta, 1998, Influence of glutaraldehyde on drug release and mucoadhesive properties of chitosan microspheres, Carbohydr. Polym., 36, 81, 10.1016/S0144-8617(98)00022-8

van der Lubben, 2001, In vivo uptake of chitosan microparticles by murine Peyer's patches: visualization studies using confocal laser scanning microscopy and immuno-histochemistry, J. Drug Target., 9, 39, 10.3109/10611860108995631

van der Lubben, 2003, Chitosan microparticles for mucosal vaccination against diphtheria: oral and nasal efficacy studies in mice, Vaccine, 21, 1400, 10.1016/S0264-410X(02)00686-2

van der Lubben, 2001, Chitosan microparticles for oral vaccination: preparation, characterization and preliminary in vivo uptake studies in murine Peyer's patches, Biomaterials, 22, 687, 10.1016/S0142-9612(00)00231-3

Shikata, 2002, In vitro cellular accumulation of gadolinium incorporated into chitosan nanoparticles designed for neutron-capture therapy of cancer, Eur. J. Pharm. Biopharm., 53, 57, 10.1016/S0939-6411(01)00198-9

Tokumitsu, 2000, Gadolinium neutron-capture therapy using novel gadopentetic acid-chitosan complex nanoparticles: in vivo growth suppression of experimental melanoma solid tumor, Cancer Lett., 150, 177, 10.1016/S0304-3835(99)00388-2

Jameela, 1996, Antitumor activity of mitoxantrone-loaded chitosan microspheres against Ehrlich ascites carcinoma, J. Pharm. Pharmacol., 48, 685, 10.1111/j.2042-7158.1996.tb03951.x

Jameela, 1995, Glutaraldehyde cross-linked chitosan microspheres as a long-acting biodegradable drug-delivery vehicle-studies on the in-vitro release of mitoxantrone and in-vivo degradation of microspheres in rat muscle, Biomaterials, 16, 769, 10.1016/0142-9612(95)99639-4

Janes, 2001, Chitosan nanoparticles as delivery systems for doxorubicin, J. Control. Release, 73, 255, 10.1016/S0168-3659(01)00294-2

Lee, 1998, Preparation of chitosan self-aggregates as a gene delivery system, J. Control. Release, 51, 213, 10.1016/S0168-3659(97)00173-9

Florea, 2000, Modified chitosan oligosaccharides as transfection agents for gene therapy of cystic fibrosis, Proc. Int. Symp. Control. Release Bioact. Mater., 27, 846

Erbacher, 1998, Chitosan-based vector/DNA complexes for gene delivery: biophysical characteristics and transfection ability, Pharm. Res., 15, 1332, 10.1023/A:1011981000671

Park, 2000, Galactosylated chitosan graft-dextran as hepatocyte-targeting DNA carrier, J. Control. Release, 69, 97, 10.1016/S0168-3659(00)00298-4

Chew, 2003, Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice, Vaccine, 21, 2720, 10.1016/S0264-410X(03)00228-7

Cui, 2001, Chitosan-based nanoparticles for topical genetic immunization, J. Control. Release, 75, 409, 10.1016/S0168-3659(01)00407-2

Borchard, 2001, Chitosans for gene delivery, Adv. Drug Deliv. Rev., 52, 145, 10.1016/S0169-409X(01)00198-3

Conti, 2000, The preparation and in vivo evaluation of the wound-healing properties of chitosan microspheres, STP Pharma. Sci., 10, 101

De Campos, 2001, Chitosan nanoparticles: a new vehicle for the improvement of the delivery of drugs to the ocular surface. Application to cyclosporin A, Int. J. Pharm., 224, 159, 10.1016/S0378-5173(01)00760-8

Chandy, 2002, Changes in cisplatin delivery due to surface-coated poly(lactic acid)-poly(ɛ-caprolactone) microspheres, J. Biomater. Appl., 16, 275, 10.1106/088532802024246

Chiou, 2001, Effects of the characteristics of chitosan on controlling drug release of chitosan coated PLLA microspheres, J. Microencapsulation, 18, 613, 10.1080/02652040010019497

Thanou, 2000, Intestinal absorption of octreotide: N-trimethyl chitosan chloride (TMC) ameliorates the permeability and absorption properties of the somatostatin analogue in vitro and in vivo, J. Pharm. Sci., 89, 951, 10.1002/1520-6017(200007)89:7<951::AID-JPS13>3.0.CO;2-1

Aiedeh, 1999, Synthesis of chitosan succinate and chitosan phthalate and their evaluation as suggested matrices in orally administered, colon-specific drug delivery systems, Archiv.der Pharmazie, 332, 103, 10.1002/(SICI)1521-4184(19993)332:3<103::AID-ARDP103>3.0.CO;2-U

Sakkinen, 2002, In vitro evaluation of microcrystalline chitosan (MCCh) as gel-forming excipient in matrix granules, Eur. J. Pharm. Biopharm., 54, 33, 10.1016/S0939-6411(02)00019-X

Muzzarelli, 1988, The biological activity of chitosan: ultrastructural study, Biomaterials, 8, 247, 10.1016/0142-9612(88)90092-0

Muzzarelli, 1992, Depolymerization of methylpyrrolidinone chitosan by lysozyme, Carbohydr. Polym., 19, 29, 10.1016/0144-8617(92)90051-Q

Muzzarelli, 1992, In vivo biochemical significance of chitin-based medical items, 179

Chen, 2003, O/W emulsification for the self-aggregation and nanoparticle formation of linoleic acids modified chitosan in the aqueous system, J. Agric. Food Chem., 51, 3135, 10.1021/jf0208482

Shanta, 2002, Synthesis and characterization of chemically modified chitosan microspheres, Carbohydr. Polym., 48, 247, 10.1016/S0144-8617(01)00244-2

Zhang, 2004, Synthesis, characterization and microsphere formation of galactosylated chitosan, J. Appl. Polym. Sci., 91, 659, 10.1002/app.13232