Recent advances in ultrasound in the diagnosis and evaluation of the activity of hepatic alveolar echinococcosis

Brunetti E, Kern P, Vuitton DA (2010) Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans. Acta Trop 114(1):1–16. https://doi.org/10.1016/j.actatropica.2009.11.001 Bulakci M et al (2016) Multimodality imaging in diagnosis and management of alveolar echinococcosis: an update. Diagn Interv Radiol 22(3):247–256. https://doi.org/10.5152/dir.2015.15456 Cai D, Li Y, Jiang Y, Wang H, Wang X, Song B (2019) The role of contrast-enhanced ultrasound in the diagnosis of hepatic alveolar echinococcosis. Medicine (baltimore) 98(5):e14325. https://doi.org/10.1097/MD.0000000000014325 Cai DM, Wang HY, Wang XL, Jiang Y, Luo Y, Li YZ (2017) Ultrasonographic findings of small lesion of hepatic alveolar echinococcosis. Acta Trop 174:165–170. https://doi.org/10.1016/j.actatropica.2016.01.030 Cairang Y et al (2017) Efficacy and safety of ultrasound-guided percutaneous microwave ablation for the treatment of hepatic alveolar echinococcosis: a preliminary study. Medicine (baltimore) 96(27):e7137. https://doi.org/10.1097/MD.0000000000007137 Calame P, Doussot A, Turco C, Colpart P, Heyd B, Delabrousse E (2021) Local invasion of hepatic alveolar echinococcosis should not be underestimated: lessons learned from imaging-pathologic correlation. Diagn Interv Imaging 102(3):189–192. https://doi.org/10.1016/j.diii.2021.01.002 Chouhan MD, Wiley E, Chiodini PL, Amin Z (2019) Hepatic alveolar hydatid disease (Echinococcus multilocularis), a mimic of liver malignancy: a review for the radiologist in non-endemic areas. Clin Radiol 74(4):247–256. https://doi.org/10.1016/j.crad.2019.01.007 Claudon M et al (2013) Guidelines and good clinical practice recommendations for contrast enhanced ultrasound (CEUS) in the liver—update 2012: a WFUMB-EFSUMB initiative in cooperation with representatives of AFSUMB, AIUM, ASUM. FLAUS and ICUS Ultraschall Med 34(1):11–29. https://doi.org/10.1055/s-0032-1325499 Dezsényi B et al (2021) Emerging human alveolar echinococcosis in Hungary (2003–2018): a retrospective case series analysis from a multi-centre study. BMC Infect Dis 21(1):168. https://doi.org/10.1186/s12879-021-05859-5 Dietrich CF et al (2020a) Cystic and alveolar echinococcosis of the hepatobiliary tract—the role of new imaging techniques for improved diagnosis. Med Ultrason 22(1):75–84. https://doi.org/10.11152/mu-2421 Dietrich CF et al (2020b) Guidelines and good clinical practice recommendations for contrast-enhanced ultrasound (CEUS) in the liver-update 2020 WFUMB in cooperation with EFSUMB, AFSUMB, AIUM, and FLAUS. Ultrasound Med Biol 46(10):2579–2604. https://doi.org/10.1016/j.ultrasmedbio.2020.04.030 Ehrhardt AR et al (2007) Assessment of disease activity in alveolar echinococcosis: a comparison of contrast enhanced ultrasound, three-phase helical CT and [(18)F] fluorodeoxyglucose positron emission tomography. Abdom Imaging 32(6):730–736. https://doi.org/10.1007/s00261-007-9177-510.1007/s00261-006-9173-1 Fischer I, Graeter T, Kratzer W, Stark K, Schlingeloff P, Schmidberger J (2020) Distribution of alveolar echinococcosis according to environmental and geographical factors in Germany, 1992–2018. Acta Trop 212:105654. https://doi.org/10.1016/j.actatropica.2020.105654 Gottstein B et al (2014) Echinococcus metacestode: in search of viability markers. Parasite 21:63. https://doi.org/10.1051/parasite/2014063 Graeter T et al (2020a) Hepatic alveolar echinococcosis: correlation between computed tomography morphology and inflammatory activity in positron emission tomography. Sci Rep 10(1):11808. https://doi.org/10.1038/s41598-020-68624-9 Graeter T et al (2020b) Intrahepatic manifestation and distant extrahepatic disease in alveolar echinococcosis: a multicenter cohort study. Acta Radiol (Stockholm, Sweden: 1987):284185120951958. https://doi.org/10.1177/0284185120951958 Grimm J et al (2020) Combining computed tomography and histology leads to an evolutionary concept of hepatic alveolar echinococcosis. Pathogens (Basel, Switzerland) 9(8). https://doi.org/10.3390/pathogens9080634 Husmann L et al (2021) PET/CT helps to determine treatment duration in patients with resected as well as inoperable alveolar echinococcosis. Parasitol Int 83:102356. https://doi.org/10.1016/j.parint.2021.102356 Kaltenbach TE et al (2015) Determination of vitality of liver lesions by alveolar echinococcosis. Comparison of parametric contrast enhanced ultrasound (SonoVue(R)) with quantified 18F-FDG-PET-CT. Nuklearmedizin 54(1):43–9. https://doi.org/10.3413/Nukmed-0670-14-05 Kantarci M et al (2012) Alveolar echinococcosis: spectrum of findings at cross-sectional imaging. Radiographics 32(7):2053–2070. https://doi.org/10.1148/rg.327125708 Kern P et al (2017) The echinococcoses: diagnosis, clinical management and burden of disease. Adv Parasitol 96:259–369. https://doi.org/10.1016/bs.apar.2016.09.006 Kim TH, Kim SY, Tang A, Lee JM (2019a) Comparison of international guidelines for noninvasive diagnosis of hepatocellular carcinoma: 2018 update. Clin Mol Hepatol 25(3):245–263. https://doi.org/10.3350/cmh.2018.0090 Kim TH, Yoon JH, Lee JM (2019b) Emerging role of hepatobiliary magnetic resonance contrast media and contrast-enhanced ultrasound for noninvasive diagnosis of hepatocellular carcinoma: emphasis on recent updates in major guidelines. Korean J Radiol 20(6):863–879. https://doi.org/10.3348/kjr.2018.0450 Kratzer W et al (2015) Proposal of an ultrasonographic classification for hepatic alveolar echinococcosis: echinococcosis multilocularis Ulm classification-ultrasound. World J Gastroenterol 21(43):12392–12402. https://doi.org/10.3748/wjg.v21.i43.12392 Li J, Dong J, Yang L, Li X, Song T (2018) Comparison of [18F]fluorodeoxyglucose positron emission tomography and contrast-enhanced ultrasound for evaluation of hepatic alveolar echinococcosis activity. Ultrasound Med Biol 44(11):2199–2208. https://doi.org/10.1016/j.ultrasmedbio.2018.06.010 Liu W et al (2014) Innovation in hepatic alveolar echinococcosis imaging: best use of old tools, and necessary evaluation of new ones. Parasite 21:74. https://doi.org/10.1051/parasite/2014072 Lu MD et al (2007) Comparison of contrast enhanced ultrasound and contrast enhanced CT or MRI in monitoring percutaneous thermal ablation procedure in patients with hepatocellular carcinoma: a multi-center study in China. Ultrasound Med Biol 33(11):1736–1749. https://doi.org/10.1016/j.ultrasmedbio.2007.05.004 Schwarze V, Mueller-Peltzer K, Negrao de Figueiredo G, Lindner F, Rubenthaler J, Clevert DA (2018) The use of contrast-enhanced ultrasound (CEUS) for the diagnostic evaluation of hepatic echinococcosis. Clin Hemorheol Microcirc 70(4):449–455. https://doi.org/10.3233/CH-189310 Seitz K et al (2010) Contrast-enhanced ultrasound (CEUS) for the characterization of focal liver lesions in clinical practice (DEGUM multicenter trial): CEUS vs. MRI—a prospective comparison in 269 patients. Ultraschall Med 31(5):492–9. https://doi.org/10.1055/s-0029-1245591 Seitz K (2009) Contrast-enhanced ultrasound (CEUS) for the characterization of focal liver lesions–prospective comparison in clinical practice: CEUS vs. CT (DEGUM multicenter trial) Parts of this Manuscript were presented at the Ultrasound Dreiländertreffen 2008, Davos. Ultraschall Medizin - Eur J Ultrasound 30(04):383–389. https://doi.org/10.1055/s-0028-1109673 Stumpe KD et al (2007) F-18-fluorodeoxyglucose (FDG) positron-emission tomography of Echinococcus multilocularis liver lesions: prospective evaluation of its value for diagnosis and follow-up during benzimidazole therapy. Infection 35(1):11–18. https://doi.org/10.1007/s15010-007-6133-9 Sulima M et al (2019) Ultrasound images in hepatic alveolar echinococcosis and clinical stage of the disease. Adv Med Sci 64(2):324–330. https://doi.org/10.1016/j.advms.2019.04.002 Tao S, Qin Z, Hao W, Yongquan L, Lanhui Y, Lei Y (2011) Usefulness of gray-scale contrast-enhanced ultrasonography (SonoVue(R)) in diagnosing hepatic alveolar echinococcosis. Ultrasound Med Biol 37(7):1024–1028. https://doi.org/10.1016/j.ultrasmedbio.2011.04.014 Tranquart F et al (2009) Real-time contrast-enhanced ultrasound in the evaluation of focal liver lesions: diagnostic efficacy and economical issues from a French multicentric study. J Radiol 90(1 Pt 2):109–122. https://doi.org/10.1016/s0221-0363(09)70089-7 Trillaud H et al (2009) Characterization of focal liver lesions with SonoVue-enhanced sonography: international multicenter-study in comparison to CT and MRI. World J Gastroenterol 15(30):3748–3756. https://doi.org/10.3748/wjg.15.3748 Wa ZC et al (2020) Differential diagnosis between hepatic alveolar echinococcosis and intrahepatic cholangiocarcinoma with conventional ultrasound and contrast-enhanced ultrasound. BMC Med Imaging 20(1):101. https://doi.org/10.1186/s12880-020-00499-8 Wang Q et al (2020) Disease burden of echinococcosis in Tibetan communities—a significant public health issue in an underdeveloped region of western China. Acta Trop 203:105283. https://doi.org/10.1016/j.actatropica.2019.105283 Zeng H, Wang J, Xie W, Liu W, Wen H (2012) Assessment of early hepatic echinococcus multilocularis infection in rats with real-time contrast-enhanced ultrasonography. Ultrasound Med Biol 38(11):1982–1988. https://doi.org/10.1016/j.ultrasmedbio.2012.07.007