Recent advances in modeling sleep: from the clinic to society and disease

Edelstein-Keshet, 2005 Forger, 2017 Asgari-Targhi, 2019, Mathematical modeling of circadian rhythms, Wiley Interdiscip Rev Syst Biol Med, 11, 1, 10.1002/wsbm.1439 Brown, 2010, General anesthesia, sleep, and coma, N Engl J Med, 363, 2638, 10.1056/NEJMra0808281 Diekelmann, 2010, The memory function of sleep, Nat Rev Neurosci, 10.1038/nrn2762 Saper, 2017, Wake–sleep circuitry: an overview, Curr Opin Neurobiol, 44, 186, 10.1016/j.conb.2017.03.021 Takahashi, 2017, Transcriptional architecture of the mammalian circadian clock, Nat Rev Genet, 18, 164, 10.1038/nrg.2016.150 Huber, 2004, Local sleep and learning, Nature, 430, 78, 10.1038/nature02663 Walker, 2006, Sleep, memory, and plasticity, Annu Rev Psychol, 57, 139, 10.1146/annurev.psych.56.091103.070307 Abel, 2013, Sleep, plasticity and memory from molecules to whole-brain networks, Curr Biol, 23, R774, 10.1016/j.cub.2013.07.025 Czeisler, 1995, Use of bright light to treat maladaptation to night shift work and circadian rhythm sleep disorders, J Sleep Res, 4, 70, 10.1111/j.1365-2869.1995.tb00231.x Hastings, 2018, Generation of circadian rhythms in the suprachiasmatic nucleus, Nat Rev Neurosci, 19, 453, 10.1038/s41583-018-0026-z Mazuski, 2018, Entrainment of circadian rhythms depends on firing rates and neuropeptide release of VIP SCN neurons, Neuron, 99, 555, 10.1016/j.neuron.2018.06.029 Bass, 2012, Circadian topology of metabolism, Nature, 491, 348, 10.1038/nature11704 Dijk, 1995, Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves, and sleep spindle activity in humans, J Neurosci, 15, 3526, 10.1523/JNEUROSCI.15-05-03526.1995 Borbely, 1982, A two process model of sleep regulation, Hum Neurobiol, 1, 195 Daan, 1984, Timing of human sleep: recovery process gated by a circadian pacemaker, Am J Physiol Regul Integr Comp Physiol, 15 Enright, 1980, Temporal precision in circadian systems: a reliable neuronal clock from unreliable components?, Science, 209, 1542, 10.1126/science.7433976 Tobler, 1983, The effect of sleep deprivation on sleep in rats with suprachiasmatic lesions, Neurosci Lett, 42, 49, 10.1016/0304-3940(83)90420-2 Trachsel, 1992, Sleep homeostasis in suprachiasmatic nuclei-lesioned rats: effects of sleep deprivation and triazolam administration, Brain Res, 589, 253, 10.1016/0006-8993(92)91284-L Borbély, 2016, The two-process model of sleep regulation: a reappraisal, J Sleep Res, 25, 131, 10.1111/jsr.12371 Achermann, 1993, A model of human sleep homeostasis based on EEG slow-wave activity: quantitative comparison of data and simulations, Brain Res Bull, 31, 97, 10.1016/0361-9230(93)90016-5 Zavada, 2009, Evidence for differential human slow-wave activity regulation across the brain, J Sleep Res, 18, 3, 10.1111/j.1365-2869.2008.00696.x Rusterholz, 2011, Topographical aspects in the dynamics of sleep homeostasis in young men: individual patterns, BMC Neurosci, 12, 10.1186/1471-2202-12-84 Guillaumin, 2018, Cortical region-specific sleep homeostasis in mice: effects of time of day and waking experience, Sleep, 41, 10.1093/sleep/zsy079 Dijk, 1999, Commentary: models of sleep regulation: successes and continuing challenges, J Biol Rhythms, 14, 571, 10.1177/074873099129000902 Jewett, 1999, Interactive mathematical models of subjective alertness and cognitive throughput in humans, J Biol Rhythms, 588, 10.1177/074873099129000920 Vyazovskiy, 2007, Sleep homeostasis in the rat in the light and dark period, Brain Res Bull, 74, 37, 10.1016/j.brainresbull.2007.05.001 Shiromani, 2004, Sleep rhythmicity and homeostasis in mice with targeted disruption of mPeriod genes, Am J Physiol Regul Integr Comp Physiol, 287, 47, 10.1152/ajpregu.00138.2004 Deboer, 2018, Sleep homeostasis and the circadian clock: do the circadian pacemaker and the sleep homeostat influence each other’s functioning?, Neurobiol Sleep Circadian Rhythm, 5, 68, 10.1016/j.nbscr.2018.02.003 Bes, 2009, Modeling napping, post-lunch dip, and other variations in human sleep propensity, Sleep, 32, 392, 10.1093/sleep/32.3.392 Åkerstedt, 2008, Predicting road crashes from a mathematical model of alertness regulation-the sleep/wake predictor, Accid Anal Prev, 40, 1480, 10.1016/j.aap.2008.03.016 Klerman, 2007, Review: on mathematical modeling of circadian rhythms, performance, and alertness, J Biol Rhythms, 22, 91, 10.1177/0748730407299200 Van Dongen, 2004, Comparison of model predictions to experimental data: rectifying false impressions, Aviat Space Environ Med, 75, A122 Cohen, 2010, Uncovering residual effects of chronic sleep loss on human performance, Sci Transl Med, 2, 10.1126/scitranslmed.3000458 McCauley, 2009, A new mathematical model for the homeostatic effects of sleep loss on neurobehavioral performance, J Theor Biol, 256, 227, 10.1016/j.jtbi.2008.09.012 Ramakrishnan, 2016, A unified model of performance: validation of its predictions across different sleep/wake schedules, Sleep, 39, 249, 10.5665/sleep.5358 McCauley, 2013, Dynamic circadian modulation in a biomathematical model for the effects of sleep and sleep loss on waking neurobehavioral performance, Sleep, 36, 1987, 10.5665/sleep.3246 St Hilaire, 2017, Modeling neurocognitive decline and recovery during repeated cycles of extended sleep and chronic sleep deficiency, Sleep, 40, 10.1093/sleep/zsw009 Skeldon, 2016, Modelling changes in sleep timing and duration across the lifespan: changes in circadian rhythmicity or sleep homeostasis?, Sleep Med Rev, 28, 96, 10.1016/j.smrv.2015.05.011 Tucker, 2007, Trait interindividual differences in the sleep physiology of healthy young adults, J Sleep Res, 16, 170, 10.1111/j.1365-2869.2007.00594.x Ramakrishnan, 2015, Can a mathematical model predict an individual’s trait-like response to both total and partial sleep loss?, J Sleep Res, 24, 262, 10.1111/jsr.12272 Holst, 2016, Sleep pharmacogenetics: personalized sleep-wake therapy, Annu Rev Pharmacol Toxicol, 56, 577, 10.1146/annurev-pharmtox-010715-103801 Phillips, 2010, Probing the mechanisms of chronotype using quantitative modeling, J Biol Rhythms, 25, 217, 10.1177/0748730410369208 Swaminathan, 2017, Are individual differences in sleep and circadian timing amplified by use of artificial light sources?, J Biol Rhythms, 32, 165, 10.1177/0748730417699310 Skeldon, 2017, The effects of self-selected light-dark cycles and social constraints on human sleep and circadian timing: a modeling approach, Sci Rep, 7, 1, 10.1038/srep45158 Phillips, 2019, High sensitivity and interindividual variability in the response of the human circadian system to evening light, Proc Natl Acad Sci U S A, 116, 12019, 10.1073/pnas.1901824116 Dijk, 2010, PERIOD3, circadian phenotypes, and sleep homeostasis, Sleep Med Rev, 14, 151, 10.1016/j.smrv.2009.07.002 Ashbrook, 2019, Genetics of the human circadian clock and sleep homeostat, Neuropsychopharmacology, 45, 45, 10.1038/s41386-019-0476-7 Fulcher, 2014, A physiologically based model of orexinergic stabilization of sleep and wake, PLoS One, 9, 10.1371/journal.pone.0091982 Ramakrishnan, 2016, A unified model of performance for predicting the effects of sleep and caffeine, Sleep, 39, 1827, 10.5665/sleep.6164 Klerman, 2016, Applying mathematical models to predict resident physician performance and alertness on traditional and novel work schedules, BMC Med Educ, 16, 1, 10.1186/s12909-016-0751-9 Hursh, 2006 Dean, 2007, Developing mathematical models of neurobehavioral performance for the “real world,”, J Biol Rhythms, 22, 246, 10.1177/0748730407301376 Hursh, 2004, Fatigue models for applied research in warfighting, Aviat Sp Environ Med, 75, A44 Caldwell, 2012, Crew schedules, sleep deprivation, and aviation performance, Curr Dir Psychol Sci, 21, 85, 10.1177/0963721411435842 Postnova, 2012, Exploring sleepiness and entrainment on permanent shift schedules in a physiologically based model, J Biol Rhythms, 27, 91, 10.1177/0748730411419934 Sano, 2015, Recognizing academic performance, sleep quality, stress level, and mental health using personality traits, wearable sensors and mobile phones, 1 Hysing, 2016, Sleep and academic performance in later adolescence: results from a large population-based study, J Sleep Res, 25, 318, 10.1111/jsr.12373 Phillips, 2017, Irregular sleep/wake patterns are associated with poorer academic performance and delayed circadian and sleep/wake timing, Sci Rep, 7, 1, 10.1038/s41598-017-03171-4 Walch, 2016, A global quantification of “normal” sleep schedules using smartphone data, Sci Adv, 2, 10.1126/sciadv.1501705 Stone, 2019, Application of a limit-cycle oscillator model for prediction of circadian phase in rotating night shift workers, Sci Rep, 9, 1, 10.1038/s41598-019-47290-6 Serkh, 2014, Optimal schedules of light exposure for rapidly correcting circadian misalignment, PLoS Comput Biol, 10, 10.1371/journal.pcbi.1003523 Zhang, 2016, Light-based circadian rhythm control: entrainment and optimization, Automatica, 68, 44, 10.1016/j.automatica.2016.01.052 Diekman, 2018, Reentrainment of the circadian pacemaker during jet lag: east-west asymmetry and the effects of north-south travel, J Theor Biol, 437, 261, 10.1016/j.jtbi.2017.10.002 Abel, 2019, Pharmaceutical-based entrainment of circadian phase via nonlinear model predictive control, Automatica, 100, 336, 10.1016/j.automatica.2018.11.012 Cederroth, 2019, Medicine in the fourth dimension, Cell Metab, 30, 238, 10.1016/j.cmet.2019.06.019 Phillips, 2007, A quantitative model of sleep-wake dynamics based on the physiology of the brainstem ascending arousal system, J Biol Rhythms, 22, 167, 10.1177/0748730406297512 Booth, 2014, Physiologically-based modeling of sleep-wake regulatory networks, Math Biosci, 250, 54, 10.1016/j.mbs.2014.01.012 Saper, 2010, Sleep state switching, Neuron, 68, 1023, 10.1016/j.neuron.2010.11.032 Phillips, 2010, Mammalian sleep dynamics: how diverse features arise from a common physiological framework, PLoS Comput Biol, 6, 1, 10.1371/journal.pcbi.1000826 Diniz Behn, 2007, A mathematical model of network dynamics governing sleep-wake patterns in mice, J Neurophysiol, 97, 3828, 10.1152/jn.01184.2006 Diniz Behn, 2008, Delayed orexin signaling consolidates wakefulness and sleep: physiology and modeling, J Neurophysiol, 99, 3090, 10.1152/jn.01243.2007 Postnova, 2009, A mathematical model of homeostatic regulation of sleep-wake cycles by hypocretin/orexin, J Biol Rhythms, 24, 523, 10.1177/0748730409346655 Behn, 2010, Simulating microinjection experiments in a novel model of the rat sleep-wake regulatory network, J Neurophysiol, 103, 1937, 10.1152/jn.00795.2009 Postnova, 2018, Prediction of cognitive performance and subjective sleepiness using a model of arousal dynamics, J Biol Rhythms, 33, 203, 10.1177/0748730418758454 Postnova, 2019, Sleep modelling across physiological levels, Clocks Sleep, 1, 166, 10.3390/clockssleep1010015 Pace-Schott, 2015, Sleep and REM sleep disturbance in the pathophysiology of PTSD: the role of extinction memory, Biol Mood Anxiety Disord, 5, 1, 10.1186/s13587-015-0018-9 Fifel, 2017, Alterations of the circadian system in Parkinson’s disease patients, Mov Disord, 10.1002/mds.26865 Roh, 2012, Disruption of the sleep-wake cycle and diurnal fluctuation of amyloid-β in mice with Alzheimer’s disease pathology, Sci Transl Med, 4, 10.1126/scitranslmed.3004291 Rijo-Ferreira, 2018, Sleeping sickness is a circadian disorder, Nat Commun, 9, 10.1038/s41467-017-02484-2 Rempe, 2018, Mathematical modeling of sleep state dynamics in a rodent model of shift work, Neurobiol Sleep Circadian Rhythm, 5, 37, 10.1016/j.nbscr.2018.04.002 Kronauer, 1999, Quantifying human circadian pacemaker response to brief, extended, and repeated light stimuli over the phototopic range, J Biol Rhythms, 14, 500, 10.1177/074873099129001073 Phillips, 2008, Sleep deprivation in a quantitative physiologically based model of the ascending arousal system, J Theor Biol, 255, 413, 10.1016/j.jtbi.2008.08.022 Best, 2007, Neuronal models for sleep-wake regulation and synaptic reorganization in the sleeping hippocampus, J Biol Rhythms, 220, 10.1177/0748730407301239 Williams, 2011, Dynamic interactions between orexin and dynorphin may delay onset of functional orexin effects: a modeling study, J Biol Rhythms, 26, 171, 10.1177/0748730410395471 Wolf, 2016, Synaptic plasticity model of therapeutic sleep deprivation in major depression, Sleep Med Rev, 30, 53, 10.1016/j.smrv.2015.11.003 Schoch, 2017, Dysregulation of sleep behavioral states in narcolepsy, Sleep, 40, 10.1093/sleep/zsx170 Proserpio, 2018, Integrating sleep and Alzheimer’s disease pathophysiology: hints for sleep disorders management, J Alzheimer’s Dis, 63, 871, 10.3233/JAD-180041 Tonetti, 2018, Circadian activity rhythm in adult attention-deficit hyperactivity disorder, J Psychiatr Res, 103, 1, 10.1016/j.jpsychires.2018.05.002