Recent advances in bone tissue engineering scaffolds

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Cao, 2010, A biodegradable porous composite scaffold of PGA/β-TCP for bone tissue engineering, Bone, 46, 386, 10.1016/j.bone.2009.09.031

Cao, 2005, The BMP signaling and in vivo bone formation, Gene, 357, 1, 10.1016/j.gene.2005.06.017

Pollak, 2012, The insulin and insulin-like growth factor receptor family in neoplasia: an update, Nat. Rev. Cancer, 12, 159, 10.1038/nrc3215

Li, 2011, Repair of rat cranial bone defects with nHAC/PLLA and BMP-2-related peptide or rhBMP-2, J. Orthop. Res., 29, 1745, 10.1002/jor.21439

Rouwkema, 2008, Vascularization in tissue engineering, Trends Biotechnol., 26, 434, 10.1016/j.tibtech.2008.04.009

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Garcia, 2012, Temporal and spatial vascularization patterns of unions and nonunions: role of vascular endothelial growth factor and bone morphogenetic proteins, J. Bone Joint Surg. Am., 94, 49, 10.2106/JBJS.J.00795

Wernike, 2010, VEGF incorporated into calcium phosphate ceramics promotes vascularisation and bone formation in vivo, Eur. Cell Mater., 19, 30, 10.22203/eCM.v019a04

Clarkin, 2008, Evaluation of VEGF-mediated signaling in primary human cells reveals a paracrine action for VEGF in osteoblast-mediated crosstalk to endothelial cells, J. Cell. Physiol., 214, 537, 10.1002/jcp.21234

Li, 2009, Effect of cell-based VEGF gene therapy on healing of a segmental bone defect, J. Orthop. Res., 27, 8, 10.1002/jor.20658

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Darsell, 2003, From CT scan to ceramic bone graft, J. Am. Ceram. Soc., 86, 1076, 10.1111/j.1151-2916.2003.tb03427.x

Hutmacher, 2004, Scaffold-based tissue engineering: rationale for computer-aided design and solid free-form fabrication systems, Trends Biotechnol., 22, 354, 10.1016/j.tibtech.2004.05.005

Fielding, 2012, Effects of silica and zinc oxide doping on mechanical and biological properties of 3D printed tricalcium phosphate tissue engineering scaffolds, Dent Mater., 28, 113, 10.1016/j.dental.2011.09.010

Tarafder, S. et al. Microwave-sintered 3D printed tricalcium phosphate scaffolds for bone tissue engineering. J. Tissue Eng. Regen. Med. http://dx.doi.org/10.1002/term.555

Balla, 2010, Porous tantalum structures for bone implants: Fabrication, mechanical and in vitro biological properties, Acta Biomater., 6, 3349, 10.1016/j.actbio.2010.01.046

Xue, 2007, Processing and biocompatibility evaluation of laser processed porous titanium, Acta Biomater., 3, 1007, 10.1016/j.actbio.2007.05.009

Rezwan, 2006, Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering, Biomaterials, 27, 3413, 10.1016/j.biomaterials.2006.01.039

Holzwarth, 2011, Biomimetic nanofibrous scaffolds for bone tissue engineering, Biomaterials, 32, 9622, 10.1016/j.biomaterials.2011.09.009

Luo, 2010, A novel method of selecting solvents for polymer electrospinning, Polymer, 51, 1654, 10.1016/j.polymer.2010.01.031

Seyednejad, 2011, An electrospun degradable scaffold based on a novel hydrophilic polyester for tissue-engineering applications, Macromol. Biosci., 11, 1684, 10.1002/mabi.201100229

Phipps, 2012, Increasing the pore sizes of bone-mimetic electrospun scaffolds comprised of polycaprolactone, collagen I and hydroxyapatite to enhance cell infiltration, Biomaterials, 33, 524, 10.1016/j.biomaterials.2011.09.080

Cicotte, 2010, Synthesis and electrospun fiber mats of low T(g) poly(propylene fumerate-co-propylene maleate), J. Appl. Polym. Sci., 117, 1984, 10.1002/app.32014

Karageorgiou, 2005, Porosity of 3D biomaterial scaffolds and osteogenesis, Biomaterials, 26, 5474, 10.1016/j.biomaterials.2005.02.002

Teixeira, 2010, In vivo evaluation of highly macroporous ceramic scaffolds for bone tissue engineering, J. Biomed. Mater. Res., 93A, 567, 10.1002/jbm.a.32532

Woodard, 2007, The mechanical properties and osteoconductivity of hydroxyapatite bone scaffolds with multi-scale porosity, Biomaterials, 28, 45, 10.1016/j.biomaterials.2006.08.021

Banerjee, 2010, Understanding the influence of MgO and SrO binary doping on the mechanical and biological properties of β-TCP ceramics, Acta Biomater., 6, 4167, 10.1016/j.actbio.2010.05.012

Bose, 2011, Understanding in vivo response and mechanical property variation in MgO, SrO and SiO2 doped β-TCP, Bone, 48, 1282, 10.1016/j.bone.2011.03.685

Shie, 2011, The role of silicon in osteoblast-like cell proliferation and apoptosis, Acta Biomater., 7, 2604, 10.1016/j.actbio.2011.02.023

Jones, 2006, Optimising bioactive glass scaffolds for bone tissue engineering, Biomaterials, 27, 964, 10.1016/j.biomaterials.2005.07.017

Miguel, 2010, Enhanced osteoblastic activity and bone regeneration using surface-modified porous bioactive glass scaffolds, J. Biomed. Mater. Res. Part A, 94A, 1023, 10.1002/jbm.a.32773

Wu, 2012, Hypoxia-mimicking mesoporous bioactive glass scaffolds with controllable cobalt ion release for bone tissue engineering, Biomaterials, 33, 2076, 10.1016/j.biomaterials.2011.11.042

Lichte, 2011, Scaffolds for bone healing: concepts, materials and evidence, Injury, 42, 569, 10.1016/j.injury.2011.03.033

Lee, 2007, Matrices and scaffolds for delivery of bioactive molecules in bone and cartilage tissue engineering, Adv. Drug Deliv. Rev., 59, 339, 10.1016/j.addr.2007.03.016

Yan, 2011, Cross-linking characteristics and mechanical properties of an injectable biomaterial composed of polypropylene fumarate and polycaprolactone co-polymer, J. Biomater. Sci. Polym. Ed., 22, 489, 10.1163/092050610X487765

Cheung, 2007, A critical review on polymer-based bio-engineered materials for scaffold development, Compos. Part B: Eng., 38, 291, 10.1016/j.compositesb.2006.06.014

Xue, 2009, Polycaprolactone coated porous tricalcium phosphate scaffolds for controlled release of protein for tissue engineering, J. Biomed. Mater. Res. Part B: Appl. Biomater., 91B, 831, 10.1002/jbm.b.31464

Laschke, 2010, In vitro and in vivo evaluation of a novel nanosize hydroxyapatite particles/poly(ester-urethane) composite scaffold for bone tissue engineering, Acta Biomater., 6, 2020, 10.1016/j.actbio.2009.12.004

Roohani-Esfahani, 2010, The influence hydroxyapatite nanoparticle shape and size on the properties of biphasic calcium phosphate scaffolds coated with hydroxyapatite–PCL composites, Biomaterials, 31, 5498, 10.1016/j.biomaterials.2010.03.058

Dabrowski, 2010, Highly porous titanium scaffolds for orthopaedic applications, J. Biomed. Mater. Res. Part B: Appl. Biomater., 95B, 53, 10.1002/jbm.b.31682

Das, 2008, Surface modification of laser-processed porous titanium for load-bearing implants, Scripta Mater., 59, 822, 10.1016/j.scriptamat.2008.06.018

Yun, 2009, Revolutionizing biodegradable metals, Mater. Today, 12, 22, 10.1016/S1369-7021(09)70273-1

Witte, 2007, Biodegradable magnesium scaffolds: Part II: Peri-implant bone remodeling, J. Biomed. Mater. Res. Part A, 81A, 757, 10.1002/jbm.a.31293

Papadimitropoulos, 2007, Kinetics of in vivo bone deposition by bone marrow stromal cells within a resorbable porous calcium phosphate scaffold: An X-ray computed microtomography study, Biotechnol. Bioeng., 98, 271, 10.1002/bit.21418

Eniwumide, 2007, Ectopic bone formation in bone marrow stem cell seeded calcium phosphate scaffolds as compared to autograft and (cell seeded) allograft, Eur. Cell Mater., 14, 30, 10.22203/eCM.v014a03

Naito, 2011, The Effect of Mesenchymal Stem Cell Osteoblastic Differentiation on the Mechanical Properties of Engineered Bone-Like Tissue, Tissue Eng. Part A, 17, 2321, 10.1089/ten.tea.2011.0099

Thein-Han, 2011, Collagen-calcium phosphate cement scaffolds seeded with umbilical cord stem cells for bone tissue engineering, Tissue Eng. Part A, 17, 2943, 10.1089/ten.tea.2010.0674

Koob, 2011, Bone formation and neovascularization mediated by mesenchymal stem cells and endothelial cells in critical-sized calvarial defects, Tissue Eng. Part A, 17, 311, 10.1089/ten.tea.2010.0338

Kempen, 2009, Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration, Biomaterials, 30, 2816, 10.1016/j.biomaterials.2009.01.031

Patel, 2008, Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model, Bone, 43, 931, 10.1016/j.bone.2008.06.019

Young, 2009, Dose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2 on bone regeneration in a rat critical-size defect model, Tissue Eng. Part A., 15, 2347, 10.1089/ten.tea.2008.0510

Kang, 2012, Insulin-like growth factor 2 promotes osteogenic cell differentiation in the parthenogenetic murine embryonic stem cells, Tissue Eng. Part A, 18, 331, 10.1089/ten.tea.2011.0074

Bose, 2012, Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: a review, Acta Biomater., 8, 1401, 10.1016/j.actbio.2011.11.017

Verron, 2010, Calcium phosphate biomaterials as bone drug delivery systems: a review, Drug Discov. Today, 15, 547, 10.1016/j.drudis.2010.05.003

Kimelman-Bleich, 2010, Targeted gene-and-host progenitor cell therapy for nonunion bone fracture repair, Mol. Ther., 19, 53, 10.1038/mt.2010.190

Keeney, 2010, The ability of a collagen/calcium phosphate scaffold to act as its own vector for gene delivery and to promote bone formation via transfection with VEGF165, Biomaterials, 31, 2893, 10.1016/j.biomaterials.2009.12.041

Fischer, 2011, Future of local bone regeneration – protein versus gene therapy, J. Cranio-Maxillofacial Surg., 39, 54, 10.1016/j.jcms.2010.03.016

Lan Levengood, 2010, The effect of BMP-2 on micro- and macroscale osteointegration of biphasic calcium phosphate scaffolds with multiscale porosity, Acta Biomater., 6, 3283, 10.1016/j.actbio.2010.02.026

Bessa, 2008, Bone morphogenetic proteins in tissue engineering: the road from laboratory to clinic, part II (BMP delivery), J. Tissue Eng. Regen. Med., 2, 81, 10.1002/term.74

Patel, 2008, In vitro and in vivo release of vascular endothelial growth factor from gelatin microparticles and biodegradable composite scaffolds, Pharm. Res., 25, 2370, 10.1007/s11095-008-9685-1

Scaglione, 2012, Order versus disorder: in vivo bone formation within osteoconductive scaffolds, Sci. Rep., 2, 10.1038/srep00274

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Badylak, 2009, Extracellular matrix as a biological scaffold material: Structure and function, Acta Biomater., 5, 1, 10.1016/j.actbio.2008.09.013

Hynes, 2009, The extracellular matrix: not just pretty fibrils, Science, 326, 1216, 10.1126/science.1176009

Beenken, 2009, The FGF family: biology, pathophysiology and therapy, Nat. Rev. Drug Discov., 8, 235, 10.1038/nrd2792

Kachgal, 2011, Mesenchymal stem cells from adipose and bone marrow promote angiogenesis via distinct cytokine and protease expression mechanisms, Angiogenesis, 14, 47, 10.1007/s10456-010-9194-9

Lin, 2007, A highly homozygous and parthenogenetic human embryonic stem cell line derived from a one-pronuclear oocyte following in vitro fertilization procedure, Cell Res., 17, 999, 10.1038/cr.2007.97

Buijs, 2012, The role of TGF-[beta] in bone metastasis: novel therapeutic perspectives, BoneKEy Rep., 1, 10.1038/bonekey.2012.96

Grellier, 2009, Role of vascular endothelial growth factor in the communication between human osteoprogenitors and endothelial cells, J. Cell. Biochem., 106, 390, 10.1002/jcb.22018

Nomi, 2002, Principals of neovascularization for tissue engineering, Mol. Aspects Med., 23, 463, 10.1016/S0098-2997(02)00008-0

Fu, 2011, Three-dimensional visualization of bioactive glass-bone integration in a rabbit tibia model using synchrotron X-ray microcomputed tomography, Tissue Eng. Part A, 17, 3077, 10.1089/ten.tea.2011.0068

Williams, 2008, On the mechanisms of biocompatibility, Biomaterials, 29, 2941, 10.1016/j.biomaterials.2008.04.023

Murphy, 2010, The effect of mean pore size on cell attachment, proliferation and migration in collagen–glycosaminoglycan scaffolds for bone tissue engineering, Biomaterials, 31, 461, 10.1016/j.biomaterials.2009.09.063