Recent Advances in the Treatment of Acute Gastroenteritis

Fonseca, 2004, Enteral vs intravenous rehydration therapy for children with gastroenteritis: a meta-analysis of randomized controlled trials, Arch Pediatr Adolesc Med, 158, 483, 10.1001/archpedi.158.5.483 Watkinson, 1982, A lack of therapeutic response to kaolin in acute childhood diarrhoea treated with glucose electrolyte solution, J Trop Pediatr, 28, 306, 10.1093/tropej/28.6.306 Szajewska, 2006, Meta-analysis: smectite in the treatment of acute infectious diarrhoea in children, Aliment Pharmacol Ther, 23, 217, 10.1111/j.1365-2036.2006.02760.x National Institute for Health and Clinical Excellence. Diarrhoea and vomiting caused by gastroenteritis: diagnosis, assessment and management in children younger than 5 years. (Clinical guideline 84.). Published 2009. Available at: http://www.guideline.gov/summary/summary.aspx?doc_id=14445&mode=full&ss=15 Accessed June 4, 2010. Sebodo, 1982, Carbo-adsorbent (Norit) in the treatment of children with diarrhoea, Southeast Asian J Trop Med Pub Health, 13, 424 Soriano-Brucher, 1991, Bismuth subsalicylate in the treatment of acute diarrhea in children: a clinical study, Pediatrics, 87, 18, 10.1542/peds.87.1.18 Figueroa-Quintanilla, 1993, A controlled trial of bismuth subsalicylate in infants with acute watery diarrheal disease, N Engl J Med, 328, 1653, 10.1056/NEJM199306103282301 Chowdhury, 2001, The efficacy of bismuth subsalicylate in the treatment of acute diarrhoea and the prevention of persistent diarrhoea, Acta Paediatr, 90, 605, 10.1080/080352501750258630 Li, 2007, Loperamide therapy for acute diarrhea in children: systematic review and meta-analysis, PLoS Med, 4, e98, 10.1371/journal.pmed.0040098 Szajewska, 2007, Systematic review: racecadotril in the treatment of acute diarrhoea in children, Aliment Pharmacol Ther, 26, 807, 10.1111/j.1365-2036.2007.03444.x Salazar-Lindo, 2000, Racecadotril in the treatment of acute watery diarrhea in children, N Engl J Med, 343, 463, 10.1056/NEJM200008173430703 Cezard, 2001, Efficacy and tolerability of racecadotril in acute diarrhea in children, Gastroenterology, 120, 799, 10.1053/gast.2001.22544 Cojocaru, 2002, Effet du racecadotril sur le recours aux soins dans le traitement des diarrhees aigues du nourrisson et de l'enfant, Arch Pediatr, 9, 774, 10.1016/S0929-693X(01)00988-5 Santos, 2009, Use of racecadotril as outpatient treatment for acute gastroenteritis: a prospective, randomized, parallel study, J Pediatr, 155, 62, 10.1016/j.jpeds.2009.01.064 Leung, 2007, Acute gastroenteritis in children: role of anti-emetic medication for gastroenteritis-related vomiting, Paediatr Drugs, 9, 175, 10.2165/00148581-200709030-00006 Tibbs, 1968, Rectal pyrilamine-pentobarbital compared with promethazine for vomiting in children, South Med J, 61, 1068, 10.1097/00007611-196810000-00012 Hampton, 2005, Promethazine warning, JAMA, 293, 921, 10.1001/jama.293.8.921-c Van Eygen, 1979, A double-blind comparison of domperidone and metoclopramide suppositories in the treatment of nausea and vomiting in children, Postgrad Med J, 55, 36 Cubeddu, 1997, Antiemetic activity of ondansetron in acute gastroenteritis, Aliment Pharmacol Ther, 11, 185, 10.1046/j.1365-2036.1997.97269000.x Ramsook, 2002, A randomized clinical trial comparing oral ondansetron with placebo in children with vomiting from acute gastroenteritis, Ann Emerg Med, 39, 397, 10.1067/mem.2002.122706 Reeves, 2002, Ondansetron decreases vomiting associated with acute gastroenteritis: a randomized, controlled trial, Pediatrics, 109, e62, 10.1542/peds.109.4.e62 Freedman, 2006, Oral ondansetron for gastroenteritis in a pediatric emergency department, N Engl J Med, 354, 1698, 10.1056/NEJMoa055119 Stork, 2006, Emergency department treatment of viral gastritis using intravenous ondansetron or dexamethasone in children, Acad Emerg Med, 13, 1027, 10.1111/j.1553-2712.2006.tb00273.x Roslund, 2008, The role of oral ondansetron in children with vomiting as a result of acute gastritis/gastroenteritis who have failed oral rehydration therapy: a randomized controlled trial, Ann Emerg Med, 52, 22-29, 10.1016/j.annemergmed.2007.09.010 Yilmaz, 2010, Clinical trial: oral ondansetron for reducing vomiting secondary to acute gastroenteritis in children—a double-blind randomized study, Aliment Pharmacol Ther, 31, 82, 10.1111/j.1365-2036.2009.04145.x DeCamp, 2008, Use of antiemetic agents in acute gastroenteritis: a systematic review and meta-analysis, Arch Pediatr Adolesc Med, 162, 858, 10.1001/archpedi.162.9.858 Gener, 2010, Administration of ondansetron is associated with lethal outcome, Pediatrics, 125, e1514, 10.1542/peds.2009-2795 Uhlig, 2009, Dimenhydrinate in children with infectious gastroenteritis: a prospective, RCT, Pediatrics, 124, e622, 10.1542/peds.2008-1650 Isolauri, 2003, Probiotics for infectious diarrhoea, Gut, 52, 436, 10.1136/gut.52.3.436 Allen, 2004, Probiotics for treating infectious diarrhoea, Cochrane Database Syst Rev, CD003048 Salvatore, 2007, Probiotics and zinc in acute infectious gastroenteritis in children: are they effective?, Nutrition, 23, 498, 10.1016/j.nut.2007.03.008 Szajewska, 2007, Meta-analysis: Lactobacillus GG for treating acute diarrhoea in children, Aliment Pharmacol Ther, 25, 871, 10.1111/j.1365-2036.2007.03282.x Nixon, 2010, The effect of Lactobacillus GG (LGG) on acute diarrheal illness in the pediatric emergency department (PED) [abstract] Szajewska, 2007, Meta-analysis: saccharomyces boulardii for treating acute diarrhoea in children, Aliment Pharmacol Ther, 25, 257, 10.1111/j.1365-2036.2006.03202.x Walsh, 1994, Zinc: health effects and research priorities for the 1990s, Environ Health Perspect, 102, 5, 10.1289/ehp.941025 World Health Organization. Complementary feeding of young children in developing countries: a review of current scientific knowledge. Document ref. WHO/NUT/98.1. Published 1998. Available at: http://whqlibdoc.who.int/hq/1998/WHO_NUT_98.1.pdf. Accessed July 19, 2010. World Health Organization and United Nations Children Fund. Clinical management of acute diarrhoea. WHO/UNICEF joint statement. Available at: http://www.unicef.org/nutrition/files/ENAcute_Diarrhoea_reprint.pdf. Accessed June 4, 2010. Sazawal, 1995, Zinc supplementation in young children with acute diarrhea in India, N Engl J Med, 333, 839, 10.1056/NEJM199509283331304 Bhutta, 2000, Therapeutic effects of oral zinc in acute and persistent diarrhea in children in developing countries: pooled analysis of randomized controlled trials, Am J Clin Nutr, 72, 1516, 10.1093/ajcn/72.6.1516 Lazzerini, 2008, Oral zinc for treating diarrhoea in children, Cochrane Database Syst Rev, CD005436 Sachdev, 1988, A controlled trial on utility of oral zinc supplementation in acute dehydrating diarrhea in infants, J Pediatr Gastroenterol Nutr, 7, 877, 10.1097/00005176-198811000-00015 Brooks, 2005, Efficacy of zinc in young infants with acute watery diarrhea, Am J Clin Nutr, 82, 605, 10.1093/ajcn/82.3.605 Fischer Walker, 2006, Zinc supplementation for the treatment of diarrhea in infants in Pakistan, India and Ethiopia, J Pediatr Gastroenterol Nutr, 43, 357, 10.1097/01.mpg.0000232018.40907.00 Al-Sonboli, 2003, Zinc supplementation in Brazilian children with acute diarrhoea, Ann Trop Paediatr, 23, 3, 10.1179/000349803125002797 Bhatnagar, 2004, Zinc with oral rehydration therapy reduces stool output and duration of diarrhea in hospitalized children: a randomized controlled trial, J Pediatr Gastroenterol Nutr, 38, 34, 10.1097/00005176-200401000-00010 Strand, 2002, Effectiveness and efficacy of zinc for the treatment of acute diarrhea in young children, Pediatrics, 109, 898, 10.1542/peds.109.5.898 King, 2003, Managing acute gastroenteritis among children: oral rehydration, maintenance, and nutritional therapy, MMWR Recomm Rep, 52, 1 Lininger, 2003, Pediatric peripheral IV insertion success rates, Pediatr Nurs, 29, 351 Nager, 2002, Comparison of nasogastric and intravenous methods of rehydration in pediatric patients with acute dehydration, Pediatrics, 109, 566, 10.1542/peds.109.4.566 Remington, 2007, Hypodermoclysis to treat dehydration: a review of the evidence, J Am Geriatr Soc, 55, 2051, 10.1111/j.1532-5415.2007.01437.x Hechter, 1947, The clinical use of hyaluronidase in hypodermoclysis, J Pediatr, 30, 645, 10.1016/S0022-3476(47)80057-5 Thomas, 2007, Assessing the role of human recombinant hyaluronidase in gravity-driven subcutaneous hydration: the INFUSE-LR study, J Palliat Med, 10, 1312, 10.1089/jpm.2007.0126 Allen, 2009, Recombinant human hyaluronidase-enabled subcutaneous pediatric rehydration, Pediatrics, 124, e858, 10.1542/peds.2008-3588