Recent Advances Toward Pain Therapeutics

Annual Reports in Medicinal Chemistry - Tập 46 - Trang 19-32 - 2011
Philippe G. Nantermet1, Darrell A. Henze1
1Merck Research Laboratories, West Point, PA, 19486, USA

Tài liệu tham khảo

Woolf, 2011, Pain, 152, S2, 10.1016/j.pain.2010.09.030 Marchand, 2005, Nat. Rev. Neurosci., 6, 521, 10.1038/nrn1700 Clare, 2010, Expert Opin. Invest. Drugs, 19, 45, 10.1517/13543780903435340 Zuliani, 2010, Expert Opin. Ther. Patents, 20, 755, 10.1517/13543771003774118 Priest, 2009, Curr. Opin. Drug Discov. Dev., 12, 682 Bear, 2009, Curr. Opin. Drug Discov. Dev., 12, 543 Matulenko, 2009, Curr. Top. Med. Chem., 9, 362, 10.2174/156802609788317883 Zuliani, 2009, Curr. Top. Med. Chem., 9, 396, 10.2174/156802609788317856 England, 2008, Expert Opin. Invest. Drugs, 17, 1849, 10.1517/13543780802514559 Hargus, 2007, Expert Opin. Invest. Drugs, 16, 635, 10.1517/13543784.16.5.635 Marron, 2006, Annu. Rep. Med. Chem., 41, 59, 10.1016/S0065-7743(06)41004-6 Kemp, 2010, Prog. Med. Chem., 49, 81, 10.1016/S0079-6468(10)49003-7 England, 2010, Future Med. Chem., 2, 775, 10.4155/fmc.10.26 Cox, 2006, Nature, 444, 894, 10.1038/nature05413 Yang, 2004, J. Med. Genet., 41, 171, 10.1136/jmg.2003.012153 Jarvis, 2007, Proc. Natl. Acad. Sci. USA, 104, 8520, 10.1073/pnas.0611364104 Kort, 2008, J. Med. Chem., 51, 407, 10.1021/jm070637u Beaudoin, 2010 Browne, 2009, J. Biol. Chem., 284, 10523, 10.1074/jbc.M807569200 Scanio, 2010, Bioorg. Med. Chem., 18, 7816, 10.1016/j.bmc.2010.09.057 Kort, 2010, Bioorg. Med. Chem. Lett., 20, 6812, 10.1016/j.bmcl.2010.08.121 Zhang, 2010, Neuropharmacology, 59, 201, 10.1016/j.neuropharm.2010.05.009 Williams, 2007, Biochemistry, 46, 14693, 10.1021/bi7018207 For press releases, see http://ir.icagen.com/phoenix.zhtml?c=178443&p=irol-news&nyo=1 See http://clinicaltrials.gov/ct2/show/NCT01165736?term=PF-05089771&rank=2 and http://clinicaltrials.gov/ct2/show/NCT01259882?term=PF-05089771&rank=1 Inoue, 2010 Noguchi, 2011 Markworth, 2010 Watson, 2008, Biodrugs, 22, 349, 10.2165/0063030-200822060-00002 Cattaneo, 2010, Curr. Opin. Mol. Ther., 12, 94 Macdonald, 2011 Ugolini, 2007, Proc. Natl. Acad. Sci. USA, 104, 2985, 10.1073/pnas.0611253104 Ueda, 2010, J. Pharmacol. Sci., 112, 438, 10.1254/jphs.09307FP Colangelo, 2008, J. Neurosci., 28, 2698, 10.1523/JNEUROSCI.5201-07.2008 Brahimi, 2010, Biochim. Biophys. Acta, 1800, 1018, 10.1016/j.bbagen.2010.06.007 Liu, 2010, J. Med. Chem., 53, 5044, 10.1021/jm100148d Owolabi, 1999, J. Pharmacol. Exp. Ther., 289, 1271 Vohra, 2009 Colquhoun, 2004, J. Pharmacol. Exp. Ther., 310, 505, 10.1124/jpet.104.066225 Jaen, 1995, J. Med. Chem., 38, 4439, 10.1021/jm00022a008 Eibl, 2010, J. Pharmacol. Exp. Ther., 332, 446, 10.1124/jpet.109.159079 Wang, 2009, Expert Opin. Ther. Patents, 19, 305, 10.1517/13543770902721261 Wang, 2008, J. Med. Chem., 51, 4672, 10.1021/jm800343j Thress, 2009, Mol. Cancer Ther., 8, 1818, 10.1158/1535-7163.MCT-09-0036 Wu, 2010 Andrews, 2010 Foster, 2009, IDrugs, 12, 478 Ghilardi, 2011, Bone, 48, 389, 10.1016/j.bone.2010.09.019 Andrews, 2010 Haas, 2010 Allen, 2011 Ahn, 2009, Expert Opin. Drug Discov., 4, 763, 10.1517/17460440903018857 Petrosino, 2010, Curr. Opin. Invest. Drugs, 11, 51 Seierstad, 2008, J. Med. Chem., 51, 7327, 10.1021/jm800311k Johnson, 2010, ACS Med. Chem. Lett., 2, 91, 10.1021/ml100190t Langman, 2010 Gustin, 2011, Bioorg. Med. Chem. Lett., 21, 2492, 10.1016/j.bmcl.2011.02.052 Wang, 2009, J. Med. Chem., 52, 170, 10.1021/jm801042a Chobanian, 2011 Chobanian, 2010 Lin, 2009 Lin, 2009