Reactive oxygen species produced in mitochondria are involved in age-dependent changes of hematopoietic and mesenchymal progenitor cells in mice. A study with the novel mitochondria-targeted antioxidant SkQ1

Mechanisms of Ageing and Development - Tập 131 - Trang 415-421 - 2010
I.N. Shipounova1, D.A. Svinareva1, T.V. Petrova1, K.G. Lyamzaev2, B.V. Chernyak2, N.I. Drize1, V.P. Skulachev2
1National Hematological Research Center, Russian Academy of Medical Sciences, Russian Federation
2A.N. Belozersky Institute of Physico-Chemical Biology and Mitoengineering Center, Moscow State University, Russian Federation

Tài liệu tham khảo

Agapova, 2008, Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 3. Inhibitory effect of SkQ1 on tumor development from p53-deficient cells, Biochemistry (Mosc.), 73, 1300, 10.1134/S0006297908120031 Anisimov, 2008, Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 5. SkQ1 prolongs lifespan and prevents development of traits of senescence, Biochemistry (Mosc.), 73, 1329, 10.1134/S0006297908120055 Antonenko, 2008, Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 1. Cationic plastoquinone derivatives: synthesis and in vitro studies, Biochemistry (Mosc.), 73, 1273, 10.1134/S0006297908120018 Antonenko, 2008, Protective effects of mitochondria-targeted antioxidant SkQ in aqueous and lipid membrane environments, J. Membr. Biol., 222, 141, 10.1007/s00232-008-9108-6 Bakeeva, 2008, Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 2. Treatment of some ROS- and age-related diseases (heart arrhythmia, heart infarctions, kidney ischemia, and stroke), Biochemistry (Mosc.), 73, 1288, 10.1134/S000629790812002X Carrancio, 2008, Optimization of mesenchymal stem cell expansion procedures by cell separation and culture conditions modification, Exp. Hematol., 36, 1014, 10.1016/j.exphem.2008.03.012 Chertkov, 1984 Cho, 2008, A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells, Blood, 111, 5553, 10.1182/blood-2007-11-123547 Demianenko, 2010, Novel mitochondria-targeted antioxidants, “Skulachev-ion” derivatives, accelerate dermal wound healing in animals, Biochemistry (Mosc.), 75, 274, 10.1134/S000629791003003X Dexter, 1977, Conditions controlling the proliferation of haemopoietic stem cells in vitro, J. Cell. Physiol., 91, 335, 10.1002/jcp.1040910303 Doucet, 2005, Platelet lysates promote mesenchymal stem cell expansion: a safety substitute for animal serum in cell-based therapy applications, J. Cell. Physiol., 205, 228, 10.1002/jcp.20391 Drize, 2000, Changes in the hemopoietic system of mice deficient for tumor necrosis factor or lymphotoxin-alpha, Bull. Exp. Biol. Med., 130, 676, 10.1007/BF02682103 Droge, 2002, Free radicals in the physiological control of cell function, Physiol. Rev., 82, 47, 10.1152/physrev.00018.2001 Dulchavsky, 2008, Bone marrow-derived stromal cells (BMSCs) interact with fibroblasts in accelerating wound healing, J. Invest. Surg., 21, 270, 10.1080/08941930802216831 Harman, 1956, Aging: a theory based on free radical and radiation chemistry, J. Gerontol., 11, 298, 10.1093/geronj/11.3.298 Ishida, 2009, Detection of fibrocytes in human skin wounds and its application for wound age determination, Int. J. Legal Med., 123, 299, 10.1007/s00414-009-0320-4 Jang, 2007, A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche, Blood, 110, 3056, 10.1182/blood-2007-05-087759 Kasper, 2009, Insights into mesenchymal stem cell aging: involvement of antioxidant defense and actin cytoskeleton, Stem Cells, 27, 1288, 10.1002/stem.49 Kobari, 1995, Hematopoietic-promoting activity of the murine stromal cell line MS-5 is not related to the expression of the major hematopoietic cytokines, J. Cell. Physiol., 163, 295, 10.1002/jcp.1041630210 Kohler, 2009, Altered cellular dynamics and endosteal location of aged early hematopoietic progenitor cells revealed by time-lapse intravital imaging in long bones, Blood, 114, 290, 10.1182/blood-2008-12-195644 Liang, 2005, Effects of aging on the homing and engraftment of murine hematopoietic stem and progenitor cells, Blood, 106, 1479, 10.1182/blood-2004-11-4282 Moore, 2006, Stem cells and their niches, Science, 311, 1880, 10.1126/science.1110542 Moussavi-Harami, 2004, Oxygen effects on senescence in chondrocytes and mesenchymal stem cells: consequences for tissue engineering, Iowa Orthop. J., 24, 15 Muller-Sieburg, 2004, Myeloid-biased hematopoietic stem cells have extensive self-renewal capacity but generate diminished lymphoid progeny with impaired IL-7 responsiveness, Blood, 103, 4111, 10.1182/blood-2003-10-3448 Neroev, 2008, Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 4. Age-related eye disease. SkQ1 returns vision to blind animals, Biochemistry (Mosc.), 73, 1317, 10.1134/S0006297908120043 Ng, 2008, Blood, 112, 295, 10.1182/blood-2007-07-103697 Nifontova, 2008, Sensitivity of mesenchymal stem cells and their progeny to medicines used for the treatment of hematoproliferative diseases, Acta Haematol., 119, 98, 10.1159/000120440 Obukhova, 2009, Mitochondria-targeted antioxidant SkQ1 inhibits age-dependent involution of the thymus in normal and senescence-prone rats, Aging, 1, 389, 10.18632/aging.100043 Papa, 1997, Reactive oxygen species, mitochondria, apoptosis and aging, Mol. Cell. Biochem., 174, 305, 10.1023/A:1006873518427 Parmar, 2007, Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia, Proc. Natl. Acad. Sci. U.S.A., 104, 5431, 10.1073/pnas.0701152104 Peura, 2009, Bone marrow mesenchymal stem cells undergo nemosis and induce keratinocyte wound healing utilizing the HGF/c-Met/PI3K pathway, Wound Repair Regen., 17, 569, 10.1111/j.1524-475X.2009.00507.x Phinney, 2007, Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair—current views, Stem Cells, 25, 2896, 10.1634/stemcells.2007-0637 Piccoli, 2005, Characterization of mitochondrial and extra-mitochondrial oxygen consuming reactions in human hematopoietic stem cells. Novel evidence of the occurrence of NAD(P)H oxidase activity, J. Biol. Chem., 280, 26467, 10.1074/jbc.M500047200 Ploemacher, 1989, An in vitro limiting-dilution assay of long-term repopulating hematopoietic stem cells in the mouse, Blood, 74, 2755, 10.1182/blood.V74.8.2755.2755 Popova, 2010, Scavenging of reactive oxygen species in mitochondria induces myofibroblast differentiation, Antiox. Redox Signal., 10.1089/ars.2009.2949 Rossi, 2008, Stems cells and the pathways to aging and cancer, Cell, 132, 681, 10.1016/j.cell.2008.01.036 Sadovnikova, 1989, Long-term culture of bone marrow from patients with PH-positive chronic myeloid leukemia, Gematol. Transfuziol., 34, 35 Scadden, 2006, The stem-cell niche as an entity of action, Nature, 441, 1075, 10.1038/nature04957 Sethe, 2006, Aging of mesenchymal stem cells, Ageing Res. Rev., 5, 91, 10.1016/j.arr.2005.10.001 Skulachev, 2007, A biochemical approach to the problem of aging: “megaproject” on membrane-penetrating ions. The first results and prospects, Biochemistry (Mosc.), 72, 1385, 10.1134/S0006297907120139 Skulachev, 2009, An attempt to prevent senescence: a mitochondrial approach, Biochim. Biophys. Acta, 1787, 437, 10.1016/j.bbabio.2008.12.008 Stolzing, 2008, Age-related changes in human bone marrow-derived mesenchymal stem cells: consequences for cell therapies, Mech. Ageing Dev., 129, 163, 10.1016/j.mad.2007.12.002 Stolzing, 2006, Effect of reduced culture temperature on antioxidant defences of mesenchymal stem cells, Free Radic. Biol. Med., 41, 326, 10.1016/j.freeradbiomed.2006.04.018 Stolzing, 2006, Age-related impairment of mesenchymal progenitor cell function, Aging Cell, 5, 213, 10.1111/j.1474-9726.2006.00213.x Suda, 2005, Hematopoietic stem cells and their niche, Trends Immunol., 26, 426, 10.1016/j.it.2005.06.006 Taichman, 2005, Blood and bone: two tissues whose fates are intertwined to create the hematopoietic stem-cell niche, Blood, 105, 2631, 10.1182/blood-2004-06-2480 Tian, 2001, Rejuvenation of degenerative thymus by oral melatonin administration and the antagonistic action of melatonin against hydroxyl radical-induced apoptosis of cultured thymocytes in mice, J. Pineal Res., 31, 214, 10.1034/j.1600-079X.2001.310304.x Tothova, 2007, FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress, Cell, 128, 325, 10.1016/j.cell.2007.01.003 Zhou, 2008, Age-related intrinsic changes in human bone-marrow-derived mesenchymal stem cells and their differentiation to osteoblasts, Aging Cell, 7, 335, 10.1111/j.1474-9726.2008.00377.x