Rathke’s cleft cyst presenting as bilateral abducens nerve palsy

Pituitary - Tập 14 - Trang 395-399 - 2009
Vinni Grover1, Amir H. Hamrahian1, Richard A. Prayson2, Robert J. Weil3
1Department of Endocrinology, Diabetes and Metabolism, Endocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, USA
2The Department of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, USA
3The Brain Tumor and Neuro-Oncology Center, Department of Neurosurgery, The Neurological Institute, Cleveland Clinic, Cleveland, USA

Tóm tắt

We present a patient with a Rathke’s cleft cyst who presented with rapidly progressive bilateral 6th nerve palsy. A 20-year-old woman with a history of cleft palate, hypertension, and hydronephrotic kidneys presented with a one month history of headache, associated with dizziness and diplopia on horizontal gaze. Examination was significant for profound bilateral 6th nerve palsies. Magnetic resonance imaging showed a hypodense mass that filled the sella and compressed the right cavernous sinus without contacting the optic chiasm. Pituitary function was normal. An endoscopic, transnasal transsphenoidal resection of the lesion was performed; microscopic examination revealed a Rathke’s cleft cyst. Surgical excision resulted in near complete resolution of the bilateral 6th nerve palsy. Rathke’s cleft cysts are an unusual cause of bilateral sixth nerve palsy and represent a potential cause of cranial neuropathy.

Tài liệu tham khảo

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