Radix Angelica dahuricae extract ameliorates oestrogen deficiency-induced dyslipidaemia in ovariectomized (OVX) rats by modulating the gut microbiota and bile acid signalling

Phytomedicine - Tập 107 - Trang 154440 - 2022
Lin Chen1, Yanru Liu1, Zhishu Tang1,2, Zhongxing Song1, Fan Cao3, Xinbo Shi1, Pei Xie1, Peifeng Wei3, Min Li3
1Co-construction Collaborative Innovation Center for Chinese Medicine Resources Industrialization by Shaanxi & Education Ministry, State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi Innovative Drug Research Center, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712083, P R China
2China Academy of Chinese Medical Sciences, Beijing 100700, P R China
3College of Pharmacy, Shaanxi University of Chinese Medicine, Xi'an, Shaanxi 712046, P R China

Tài liệu tham khảo

Aggarwal, 2013, Probiotics and their effects on metabolic diseases: an update, J. Clin. Diagn. Res., 7, 173 Belzer, 2012, Microbes inside–from diversity to function: the case of Akkermansia, ISME J., 6, 1449, 10.1038/ismej.2012.6 Berggren, 1996, Influence of orally and rectally administered propionate on cholesterol and glucose metabolism in obese rats, Br. J. Nutr., 76, 287, 10.1079/BJN19960032 Byrne, 2015, The role of short chain fatty acids in appetite regulation and energy homeostasis, Int. J. Obes. (Lond.), 39, 1331, 10.1038/ijo.2015.84 Cani, 2019, Microbial regulation of organismal energy homeostasis, Nat. Metab., 1, 34, 10.1038/s42255-018-0017-4 Cao, 2013, Effects of imperatorin, the active component from Radix Angelicae (Baizhi), on the blood pressure and oxidative stress in 2K,1C hypertensive rats, Phytomedicine, 20, 1048, 10.1016/j.phymed.2013.04.021 Chen, 2015, Separation and simultaneous quantification of nine furanocoumarins from Radix Angelicae dahuricae using liquid chromatography with tandem mass spectrometry for bioavailability determination in rats, J. Sep. Sci., 38, 4216, 10.1002/jssc.201500840 Chen, 2020, Improvements in estrogen deficiency-induced hypercholesterolemia by Hypericum perforatum L. extract are associated with gut microbiota and related metabolites in ovariectomized (OVX) rats, Biomed. Pharmacother., 135 Chen, 2021, Improvements in estrogen deficiency-induced hypercholesterolemia by Hypericum perforatum L. extract are associated with gut microbiota and related metabolites in ovariectomized (OVX) rats, Biomed. Pharmacother., 135, 10.1016/j.biopha.2020.111131 Chen, 2018, High hepatic exposure of furanocoumarins in Radix Angelica dahuricae is associated with transporter mediated active uptake, J. Ethnopharmacol., 212, 74, 10.1016/j.jep.2017.10.014 Cornejo-Pareja, 2019, Importance of gut microbiota in obesity, Eur. J. Clin. Nutr., 72, 26, 10.1038/s41430-018-0306-8 Cox-York, 2015, Ovariectomy results in differential shifts in gut microbiota in low versus high aerobic capacity rats, Physiol. Rep., 3, 10.14814/phy2.12488 den Besten, 2013, Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids, Am. J. Physiol. Gastrointest. Liver Physiol., 305, G900, 10.1152/ajpgi.00265.2013 Derrien, 2017, Akkermansia muciniphila and its role in regulating host functions, Microb. Pathog., 106, 171, 10.1016/j.micpath.2016.02.005 Derrien, 2004, Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium, Int. J. Syst. Evol. Microbiol., 54, 1469, 10.1099/ijs.0.02873-0 Erejuwa, 2014, Modulation of gut microbiota in the management of metabolic disorders: the prospects and challenges, Int. J. Mol. Sci., 15, 4158, 10.3390/ijms15034158 Fernandes, 2014, Adiposity, gut microbiota and faecal short chain fatty acids are linked in adult humans, Nutr. Diabetes, 4, e121, 10.1038/nutd.2014.23 Gameiro, 2010, Menopause and aging: changes in the immune system–a review, Maturitas, 67, 316, 10.1016/j.maturitas.2010.08.003 Ganesh, 2013, Commensal Akkermansia muciniphila exacerbates gut inflammation in Salmonella Typhimurium-infected gnotobiotic mice, PLoS One, 8, e74963, 10.1371/journal.pone.0074963 Gerard, 2013, Metabolism of cholesterol and bile acids by the gut microbiota, Pathogens, 3, 14, 10.3390/pathogens3010014 Hara, 1999, Short-chain fatty acids suppress cholesterol synthesis in rat liver and intestine, J. Nutr., 129, 942, 10.1093/jn/129.5.942 Jakobsdottir, 2013, High-fat diet reduces the formation of butyrate, but increases succinate, inflammation, liver fat and cholesterol in rats, while dietary fibre counteracts these effects, PLoS One, 8, e80476, 10.1371/journal.pone.0080476 Jia, 2016, Estrogenic activity of osthole and imperatorin in MCF-7 cells and their osteoblastic effects in Saos-2 cells, Chin. J. Nat. Med., 14, 413 Jones, 2012, Cholesterol lowering and inhibition of sterol absorption by Lactobacillus reuteri NCIMB 30242: a randomized controlled trial, Eur. J. Clin. Nutr., 66, 1234, 10.1038/ejcn.2012.126 Jones, 2009, Probiotic Lactobacillus reuteri biofilms produce antimicrobial and anti-inflammatory factors, BMC Microbiol., 9, 35, 10.1186/1471-2180-9-35 Joyce, 2014, Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut, Proc. Natl. Acad. Sci. U. S. A., 111, 7421, 10.1073/pnas.1323599111 Kim, 2013, Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice, Gastroenterology, 145, 396, 10.1053/j.gastro.2013.04.056 Kimura, 2013, The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43, Nat. Commun., 4, 1829, 10.1038/ncomms2852 Lee, 2015, Investigation of the mechanisms of Angelica dahurica root extract-induced vasorelaxation in isolated rat aortic rings, BMC Complement. Altern. Med., 15, 395, 10.1186/s12906-015-0889-8 Lee, 2011, Anti-inflammatory activity of Angelica dahurica ethanolic extract on RAW264.7 cells via upregulation of heme oxygenase-1, Food Chem. Toxicol., 49, 1047, 10.1016/j.fct.2011.01.010 Lee, 2011, Anti-asthmatic effects of Angelica dahurica against ovalbumin-induced airway inflammation via upregulation of heme oxygenase-1, Food Chem. Toxicol., 49, 829, 10.1016/j.fct.2010.12.004 Lobo, 2017, Hormone-replacement therapy: current thinking, Nat. Rev. Endocrinol., 13, 220, 10.1038/nrendo.2016.164 Lu, 2016, Effects of Angelica dahurica on obesity and fatty liver in mice, Chin. J. Nat. Med., 14, 641 Lu, 2016, Short Chain Fatty Acids Prevent High-fat-diet-induced Obesity in Mice by Regulating G Protein-coupled Receptors and Gut Microbiota, Sci. Rep., 6, 37589, 10.1038/srep37589 Mells, 2013, The role of gastrointestinal hormones in hepatic lipid metabolism, Semin. Liver Dis., 33, 343, 10.1055/s-0033-1358527 Morrison, 2016, Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism, Gut Microbes, 7, 189, 10.1080/19490976.2015.1134082 Nelson, 2002, Postmenopausal hormone replacement therapy: scientific review, JAMA, 288, 872, 10.1001/jama.288.7.872 Pagadala, 2017, Software for molecular docking: a review, Biophys. Rev., 9, 91, 10.1007/s12551-016-0247-1 Pfeilschifter, 2002, Changes in proinflammatory cytokine activity after menopause, Endocr. Rev., 23, 90, 10.1210/edrv.23.1.0456 Piao, 2006, Estrogenic activity of furanocoumarins isolated from Angelica dahurica, Arch. Pharm. Res., 29, 741, 10.1007/BF02974073 Richards, 2016, The effects of short-chain fatty acids on the cardiovascular system, PharmaNutrition, 4, 68, 10.1016/j.phanu.2016.02.001 Rodriguez-Cabezas, 2002, Dietary fiber down-regulates colonic tumor necrosis factor alpha and nitric oxide production in trinitrobenzenesulfonic acid-induced colitic rats, J. Nutr., 132, 3263, 10.1093/jn/132.11.3263 Santos-Marcos, 2018, Influence of gender and menopausal status on gut microbiota, Maturitas, 116, 43, 10.1016/j.maturitas.2018.07.008 Scheithauer, 2020, Gut Microbiota as a Trigger for Metabolic Inflammation in Obesity and Type 2 Diabetes, Front. Immunol., 11, 10.3389/fimmu.2020.571731 Shibata, 2009, Regulation of macrophage function in inflammation and atherosclerosis, J. Lipid Res., 50, S277, 10.1194/jlr.R800063-JLR200 Stefanska, 2015, Metabolic Syndrome and Menopause: pathophysiology, Clinical and Diagnostic Significance, Adv. Clin. Chem., 72, 1, 10.1016/bs.acc.2015.07.001 Stevenson, 1993, Influence of age and menopause on serum lipids and lipoproteins in healthy women, Atherosclerosis, 98, 83, 10.1016/0021-9150(93)90225-J Tan, 2014, The role of short-chain fatty acids in health and disease, Adv. Immunol., 121, 91, 10.1016/B978-0-12-800100-4.00003-9 Tannapfel, 2011, Histopathological diagnosis of non-alcoholic and alcoholic fatty liver disease, Virchows. Arch., 458, 511, 10.1007/s00428-011-1066-1 Taranto, 2000, Effect of Lactobacillus reuteri on the prevention of hypercholesterolemia in mice, J. Dairy Sci., 83, 401, 10.3168/jds.S0022-0302(00)74895-8 Tedelind, 2007, Anti-inflammatory properties of the short-chain fatty acids acetate and propionate: a study with relevance to inflammatory bowel disease, World J. Gastroenterol., 13, 2826, 10.3748/wjg.v13.i20.2826 Turnbaugh, 2006, An obesity-associated gut microbiome with increased capacity for energy harvest, Nature, 444, 1027, 10.1038/nature05414 Vernia, 2003, Topical butyrate improves efficacy of 5-ASA in refractory distal ulcerative colitis: results of a multicentre trial, Eur. J. Clin. Invest., 33, 244, 10.1046/j.1365-2362.2003.01130.x Vieira-Potter, 2018, Soy-induced fecal metabolome changes in ovariectomized and intact female rats: relationship with cardiometabolic health, Sci. Rep., 8, 16896, 10.1038/s41598-018-35171-3 Vinolo, 2011, Regulation of inflammation by short chain fatty acids, Nutrients, 3, 858, 10.3390/nu3100858 Wang, 2019, Parabacteroides distasonis alleviates obesity and metabolic dysfunctions via production of succinate and secondary bile acids, Cell Rep., 26, 222, 10.1016/j.celrep.2018.12.028 Wright, 1990, Propionate inhibits hepatocyte lipid synthesis, Proc. Soc. Exp. Biol. Med., 195, 26, 10.3181/00379727-195-43113 Yu, 2015, Correlation between the protein expression of A-kinase anchor protein 95, cyclin D3 and AKT and pathological indicators in lung cancer tissues, Exp. Ther. Med., 10, 1175, 10.3892/etm.2015.2637 Zhang, 2020, The modulation of Luffa cylindrica (L.) Roem supplementation on gene expression and amino acid profiles in liver for alleviating hepatic steatosis via gut microbiota in high-fat diet-fed mice: insight from hepatic transcriptome analysis, J. Nutr. Biochem., 80, 10.1016/j.jnutbio.2020.108365 Zhang, 2017, Effect of curcumin on the diversity of gut microbiota in ovariectomized rats, Nutrients, 9, 10.3390/nu9101146