Radiolabeling of a monoclonal antibody with N-succinimidyl para-[77Br]bromobenzoate

D.Scott Wilbur1, Mark D Hylarides1
1NeoRx Corporation, 410 W. Harrison St, Seattle, WA 98119, U.S.A.

Tài liệu tham khảo

Bolton, 1983, The labeling of proteins to a I-125 containing acylating agent, Biochem. J., 133, 529, 10.1042/bj1330529 Eary, 1989, Radiochemistry of halogenated antibodies, 83 Haung, 1983, Halogen labeled compounds (F, Br, At, Cl), Vol. 1, 238 Knight, 1978, Sites of direct and indirect halogenation of albumin, Biochim. Biophys. Acta, 543, 185, 10.1016/0005-2795(78)90001-6 Knight, 1977, In vitro stability and in vivo clearance of fibrinogen or serum albumin labeled with 77Br, 131I, or 125I by direct or indirect synthetic methods, J. Nucl. Med., 18, 282 Knight, 1975, 77Br: a new protein label, 149 McElvany, 1980, Characterization of bromine-77-labeled proteins prepared using bromoperoxidase, J. Nucl. Med., 21, 953 McElvany, 1980, Characterization of bromine-77-labeled proteins using myeloperoxidase, Int. J. Appl. Radiat. Isot., 31, 679, 10.1016/0020-708X(80)90004-6 Otsuka, 1987, Methods to label monoclonal antibodies for use in tumor imaging, Nucl. Med. Biol., 14, 243 Rogers R. S. (1984) Medical Radioisotope Research Group, Los Alamos National Laboratory—personal communication (deceased). Welch, 1983, Radionuclides for use in biomedical studies, Radiochim. Acta, 34, 41, 10.1524/ract.1983.34.12.41 Wilbur, 1984, Radiolabeled phenylalkanoic acids for protein labeling. Investigation of arylsilanes as intermediates for radiolabeling phenylpropionic acids and acid derivatives Wilbur, 1989, Development of a stable radioiodinating reagent to label monoclonal antibodies for radiotherapy of cancer, J. Nucl. Med., 30, 216 Wilbur, 1989, Reactions of organometallic compounds with astatine-211. Application to protein labeling, Radiochim. Acta, 47, 137, 10.1524/ract.1989.47.23.137 Wood, 1975, The radioactive labeling of proteins with an iodinated amidination reagent, Analyt. Biochem., 69, 339, 10.1016/0003-2697(75)90136-0