RUNX3 derived hsa_circ_0005752 accelerates the osteogenic differentiation of adipose-derived stem cells via the miR-496/MDM2-p53 pathway

Regenerative Therapy - Tập 18 - Trang 430-440 - 2021
Ming Wang1,2, Yifan Huan3, Xiyang Li3, Jing Li1, Guohua Lv1
1Department of Spine Surgery, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan Province, PR China
2Department of Spine Surgery, The First Affiliated Hospital of University of South China, Hengyang 421001, Hunan Province, PR China
3Department of Orthopedics, Financial and Trade Hospital of Hunan Province, Changsha 410001, Hunan Province, PR China

Tài liệu tham khảo

Compston, 2019, Osteoporosis, Lancet, 393, 364, 10.1016/S0140-6736(18)32112-3 Wu, 2018, Long non-coding RNAs: a new regulatory code for osteoporosis, Front Endocrinol (Lausanne), 9, 587, 10.3389/fendo.2018.00587 Mazini, 2019, Regenerative capacity of adipose derived stem cells (ADSCs), comparison with mesenchymal stem cells (MSCs), Int J Mol Sci, 20, 10.3390/ijms20102523 Paspaliaris, 2019, Stem cells in osteoporosis: from biology to new therapeutic approaches, Stem Cell Int, 2019, 1730978 Barba, 2017, Adipose-derived stem cell therapies for bone regeneration, Expet Opin Biol Ther, 17, 677, 10.1080/14712598.2017.1315403 Lee, 2021, RUNX3 methylation drives hypoxia-induced cell proliferation and antiapoptosis in early tumorigenesis, Cell Death Differ, 28, 1251, 10.1038/s41418-020-00647-1 Hantisteanu, 2020, Runx3 prevents spontaneous colitis by directing the differentiation of anti-inflammatory mononuclear phagocytes, PloS One, 15, 10.1371/journal.pone.0233044 Li, 2020, Sphingosine-1-phosphate receptor 2 modulates pain sensitivity by suppressing the ROS-RUNX3 pathway in a rat model of neuropathy, J Cell Physiol, 235, 3864, 10.1002/jcp.29280 Mevel, 2019, RUNX transcription factors: orchestrators of development, Development, 146, 10.1242/dev.148296 Soung do, 2007, Runx3/AML2/Cbfa3 regulates early and late chondrocyte differentiation, J Bone Miner Res, 22, 1260, 10.1359/jbmr.070502 Choo, 2019, Runx3 inhibits endothelial progenitor cell differentiation and function via suppression of HIF-1alpha activity, Int J Oncol, 54, 1327 Haque, 2017, Circular RNAs (circRNAs) in Health and disease, Genes (Basel), 8, 10.3390/genes8120353 Shang, 2019, The novel roles of circRNAs in human cancer, Mol Canc, 18, 6, 10.1186/s12943-018-0934-6 Hansen, 2013, Natural RNA circles function as efficient microRNA sponges, Nature, 495, 384, 10.1038/nature11993 Salzman, 2016, Circular RNA expression: its potential regulation and function, Trends Genet, 32, 309, 10.1016/j.tig.2016.03.002 Yu, 2019, circRNA_0016624 could sponge miR-98 to regulate BMP2 expression in postmenopausal osteoporosis, Biochem Biophys Res Commun, 516, 546, 10.1016/j.bbrc.2019.06.087 Peng, 2019, Hsa_circRNA_33287 promotes the osteogenic differentiation of maxillary sinus membrane stem cells via miR-214-3p/Runx3, Biomed Pharmacother, 109, 1709, 10.1016/j.biopha.2018.10.159 Kang, 2020, Differential circular RNA expression profiling during osteogenic differentiation in human adipose-derived stem cells, Epigenomics, 12, 289, 10.2217/epi-2019-0218 Moll, 2003, The MDM2-p53 interaction, Mol Canc Res, 1, 1001 Zheng, 2020, Mdm2 promotes odontoblast-like differentiation by ubiquitinating Dlx3 and p53, J Dent Res, 99, 320, 10.1177/0022034519893672 Lengner, 2006, Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling, J Cell Biol, 172, 909, 10.1083/jcb.200508130 Daniele, 2019, Long lasting inhibition of Mdm2-p53 interaction potentiates mesenchymal stem cell differentiation into osteoblasts, Biochim Biophys Acta Mol Cell Res, 1866, 737, 10.1016/j.bbamcr.2019.01.012 Fu, 2015, Mdm2 promotes myogenesis through the ubiquitination and degradation of CCAAT/enhancer-binding protein beta, J Biol Chem, 290, 10200, 10.1074/jbc.M115.638577 Hallenborg, 2012, Mdm2 controls CREB-dependent transactivation and initiation of adipocyte differentiation, Cell Death Differ, 19, 1381, 10.1038/cdd.2012.15 Ji, 2020, The circular RNA circRNA124534 promotes osteogenic differentiation of human dental pulp stem cells through modulation of the miR-496/beta-Catenin pathway, Front Cell Dev Biol, 8, 230, 10.3389/fcell.2020.00230 Ensrud, 2017, Osteoporosis, Ann Intern Med, 167, ITC17, 10.7326/AITC201708010 Rosen, 2000 Yang, 2020, A road map for understanding molecular and genetic determinants of osteoporosis, Nat Rev Endocrinol, 16, 91, 10.1038/s41574-019-0282-7 Ralston, 2002, Genetic control of susceptibility to osteoporosis, J Clin Endocrinol Metab, 87, 2460, 10.1210/jcem.87.6.8621 Huang, 2020, Circular RNA YAP1 attenuates osteoporosis through up-regulation of YAP1 and activation of Wnt/beta-catenin pathway, Biomed Pharmacother, 129, 110365, 10.1016/j.biopha.2020.110365 Huang, 2017, IL-1beta inhibits osteogenesis of human bone marrow-derived mesenchymal stem cells by activating FoxD3/microRNA-496 to repress wnt signaling, Genesis, 55, 10.1002/dvg.23040 Wang, 2017, RUNX3 plays an important role in mediating the BMP9-induced osteogenic differentiation of mesenchymal stem cells, Int J Mol Med, 40, 1991 Saito, 2015, Runx1 and Runx3 are downstream effectors of Nanog in promoting osteogenic differentiation of the mouse mesenchymal cell line C3H10T1/2, Cell Reprogr, 17, 227, 10.1089/cell.2014.0059 Klunker, 2009, Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells, J Exp Med, 206, 2701, 10.1084/jem.20090596