RNA in situ hybridization and expression of related genes regulating the accumulation of triterpenoids in Cyclocarya paliurus

Abdelrahman, 2014, Compartmentation and localization of bioactive metabolites in different organs of Allium roylei, Biosci Biotech Bioch, 78, 1112, 10.1080/09168451.2014.915722

Bradford, 1976, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal Biochem, 72, 248, 10.1016/0003-2697(76)90527-3

Burlin, 2019, Differentially expressed long noncoding RNAs in the promoter region of the fork head gene in Drosophila melanogaster detected by northern blot hybridization, Mol Biol (Mosk), 53, 476, 10.1134/S0026893319030038

Busquets, 2008, Arabidopsis thaliana contains a single gene encoding squalene synthase, Plant Mol Biol, 67, 25, 10.1007/s11103-008-9299-3

Campbell, 2003, Pathogen-responsive expression of a putative ATP-binding cassette transporter gene conferring resistance to the diterpenoid sclareol is regulated by multiple defense signaling pathways in Arabidopsis, Plant Physiol, 133, 1272, 10.1104/pp.103.024182

Carretero-Paulet, 2006, Enhanced flux through the methylerythritol 4-phosphate pathway in Arabidopsis plants overexpressing deoxyxylulose 5-phosphate reductoisomerase, Plant Mol Biol, 62, 683, 10.1007/s11103-006-9051-9

Chappell, 1995, The biochemistry and molecular biology of isoprenoid metabolism, Plant Physiol, 107, 1, 10.1104/pp.107.1.1

Chen, 2019, Morphological characterization of flower buds development and related gene expression profiling at bud break stage in heterodichogamous Cyclocarya paliurus (Batal.) Iljinskaja, Genes (Basel), 10, 818, 10.3390/genes10100818

Chen, 2019, Localization and dynamic change of saponins in Cyclocarya paliurus (Batal.) Iljinskaja, PLoS One, 14

Cheng, 2018, Changes in the physiological characteristics and baicalin biosynthesis metabolism of Scutellaria baicalensis Georgi under drought stress, Ind Crops Prod, 122, 473, 10.1016/j.indcrop.2018.06.030

Croteau, 2000, Natural products (secondary metabolites)

Ding, 2019, Genome-wide investigation of WRKY transcription factors in sweet osmanthus and their potential regulation role in aroma synthesis, Tree Physiol, 40, 557, 10.1093/treephys/tpz129

Dubey, 2003, An overview of the non-mevalonate pathway for terpenoid biosynthesis in plants, J Biosci, 28, 637, 10.1007/BF02703339

Enfissi, 2005, Metabolic engineering of the mevalonate and non-mevalonate isopentenyl diphosphate-forming pathways for the production of health-promoting isoprenoids in tomato, Plant Biotechnol J, 3, 17, 10.1111/j.1467-7652.2004.00091.x

Fang, 2006, Methods to break seed dormancy in Cyclocarya paliurus (Batal.) Iljinskaja, Sci Hortic, 110, 305, 10.1016/j.scienta.2006.06.031

Fu, 2019, Isolation and functional analysis of squalene synthase gene in tea plant Camellia sinensis, Plant Physiol Biochem, 142, 53, 10.1016/j.plaphy.2019.06.030

Gong, 2006, Molecular cloning and expression profile analysis of Ginkgo biloba DXS gene encoding 1-deoxy-D-xylulose 5-phosphate synthase, the first committed enzyme of the 2-C-methyl-D-erythritol 4-phosphate pathway, Planta Med, 72, 329, 10.1055/s-2005-916234

He, 2017, Glandular trichome-specific expression of alcohol dehydrogenase 1 (ADH1) using a promoter-GUS fusion in Artemisia annua L, Plant Cell Tissue Organ, 130, 61, 10.1007/s11240-017-1204-9

Himmeldirk, 1996, Biosynthesis of vitamins B1 and B6 in Escherichia coli: concurrent incorporation of 1-deoxy-D-xylulose into thiamin (B1) and pyridoxol (B6), Chem Commun (Camb), 10, 1187, 10.1039/cc9960001187

Hiroaki, 2003, Up-regulation of soyasaponin biosynthesis by methyl jasmonate in cultured cells of Glycyrrhiza glabra, Plant Cell Physiol, 44, 404, 10.1093/pcp/pcg054

Jasiński, 2001, A plant plasma membrane ATP binding cassette-type transporter is involved in antifungal terpenoid secretion, Plant Cell, 13, 1095

Jin, 2015, Physiological and metabolic changes of purslane (Portulaca oleracea L.) in response to drought, heat, and combined stresses, Front Plant Sci, 6, 1123

Julliard, 1991, Biosynthesis of the thiazole moiety of thiamin (vitamin B1) in higher plant chloroplasts, Proc Natl Acad Sci USA, 88, 2042, 10.1073/pnas.88.6.2042

Julliard, 1992, Biosynthesis of the pyridoxal ring (vitamin B6) in higher plant chloroplasts and its relationship with the biosynthesis of the thiazol ring (vitamin B1), CR Acad Sci Ser III, 314, 285

Kim, 2011, Gene regulation patterns in triterpene biosynthetic pathway driven by overexpression of squalene synthase and methyl jasmonate elicitation in Bupleurum falcatum, Planta, 233, 343, 10.1007/s00425-010-1292-9

Kochan, 2019, Abscisic acid regulates the 3-hydroxy-3-methylglutaryl CoA reductase gene promoter and ginsenoside production in Panax quinquefolium hairy root cultures, Int J Mol Sci, 20, 1310, 10.3390/ijms20061310

Kulikova, 2018, In situ hybridization method for localization of mRNA molecules in Medicago tissue sections, Methods Mol Biol, 1822, 145, 10.1007/978-1-4939-8633-0_11

Kuzuyama, 1998, Fosmidomycin, a specific inhibitor of 1-deoxy-d-xylulose 5-phosphate reductoisomerase in the nonmevalonate pathway for terpenoid biosynthesis, Tetrahedron Lett, 39, 7913, 10.1016/S0040-4039(98)01755-9

Lange, 1999, Isoprenoid biosynthesis via a mevalonate-independent pathway in plants: cloning and heterologous expression of 1-Deoxy-d-xylulose-5-phosphate reductoisomerase from peppermint, Arch Biochem Biophys, 365, 170, 10.1006/abbi.1999.1168

Li, 2019, Establishment and optimization of mRNA in situ hybridization system in turnip (Brassica rapa var. rapa), Plant Methods, 15, 115, 10.1186/s13007-019-0499-4

Li, 2017, The establishment of northern blot hybridization detection system for tobacco mosaic virus liaoning isolate, Biotechnol Bull, 33, 137

Liu, 2020, 3,4-seco-dammarane triterpenoid saponins with anti-inflammatory activity isolated from the leaves of Cyclocarya paliurus, J Agric Food Chem, 68, 2041, 10.1021/acs.jafc.9b06898

Liu, 2018, Light quality affects flavonoid production and related gene expression in Cyclocarya paliurus, J Photochem Photobiol B, 179, 66, 10.1016/j.jphotobiol.2018.01.002

Livak, 2001, Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔCT method, Methods, 25, 402, 10.1006/meth.2001.1262

Munganyinka, 2018, Localization of cassava brown streak virus in Nicotiana rustica and cassava Manihot esculenta (Crantz) using RNAscope® in situ hybridization, Virol J, 15, 128, 10.1186/s12985-018-1038-z

Niinemets, 2016, Uncovering the hidden facets of drought stress: secondary metabolites make the difference, Tree Physiol, 36, 129

Ning, 2019, Identification of α -glucosidase inhibitors from Cyclocarya paliurus tea leaves by using UF-UPLC-QTOF-MSMS and molecular docking, Food Funct, 10, 1893, 10.1039/C8FO01845F

Pütter, 2017, Isoprenoid biosynthesis in dandelion latex is enhanced by the overexpression of three key enzymes involved in the mevalonate pathway, BMC Plant Biol, 17, 88, 10.1186/s12870-017-1036-0

Shen, 2006, Cloning and characterization of a root-specific expressing gene encoding 3-hydroxy-3-methylglutaryl coenzyme a reductase from Ginkgo biloba, Mol Biol Rep, 33, 117, 10.1007/s11033-006-0014-7

Shu, 1995, Studies on the sweet principles from the leaves of Cyclocarya paliurus (Batal.) Iljinskaya, Acta Pharm Sin B, 27, 841

Singh, 2014, Sterol partitioning by HMGR and DXR for routing intermediates toward withanolide biosynthesis, Physiol Plant, 152, 617, 10.1111/ppl.12213

Sun, 2020, Hypoglycemic triterpenoid glycosides from Cyclocarya paliurus (Sweet Tea Tree), Bioorg Chem, 95, 10.1016/j.bioorg.2019.103493

Wang, 2013, Trichome-specific expression of the amorpha-4, 11-diene 12-hydroxylase (cyp71av1) gene, encoding a key enzyme of artemisinin biosynthesis in Artemisia annua, as reported by a promoter-GUS fusion, Plant Mol Biol, 81, 119, 10.1007/s11103-012-9986-y

Wei, 2019, Characterization and function of 3-Hydroxy-3-Methylglutaryl-CoA reductase in Populus trichocarpa: overexpression of PtHMGR enhances terpenoids in transgenic poplar, Front Plant Sci, 10, 1476, 10.3389/fpls.2019.01476

Xie, 2018, Protective effect of flavonoids from Cyclocarya paliurus leaves against carbon tetrachloride-induced acute liver injury in mice, Food Chem Toxicol, 119, 392, 10.1016/j.fct.2018.01.016

Xu, 2002, The practical technique of in situ hybridization with RNA probe, Chin Bull Bot, 2, 107

Yang, 1992, Studies on the sweet principles from the leaves of Cyclocarya paliurus (Batal.) Iljinskaya, Acta Pharm Sin B, 30, 757

Yang, 2018, Pentacyclic triterpenoids from Cyclocarya paliurus and their antioxidant activities in FFA-induced HepG2 steatosis cells, Phytochemistry, 151, 119, 10.1016/j.phytochem.2018.03.010

Yang, 2018, Antihyperlipidemic and hepatoprotective activities of polysaccharide fraction from Cyclocarya paliurus in high-fat emulsion-induced hyperlipidaemic mice, Carbohydr Polym, 183, 11, 10.1016/j.carbpol.2017.11.033

Yang, 2019, Effects of drought-re-watering-drought on the photosynthesis physiology and secondary metabolite production of Bupleurum chinense DC, Plant Cell Rep, 38, 1181, 10.1007/s00299-019-02436-8

Yu, 2019, Research advance on the effects of environmental factors on the biosynthesis of terpenoids in plant, Acta Bot Boreali-Occident Sin, 39, 1701

Zhang, 2014, Accumulation dynamic of triterpenoid saponins in Akebia trifoliata stem, J Chin Med Mater, 37, 1130

Zheng, 2014, Triterpenoid saponin biosynthetic pathway profiling and candidate gene mining of the Ilex asprella root using RNA-Seq, Int J Mol Sci, 15, 5970, 10.3390/ijms15045970

Zhong, 1996, Studies on pentatriterpenoids of Cyclocarya paliurus, Chin Tradit Herb Drugs, 27, 387

Zhou, 2012, Accumulation dynamic of acankoreagenin in leaves of Acanthopanax gracilistylus, Chin Tradit Herb Drugs, 43, 1550