R&D investments for neglected diseases can be sensitive to the economic goal of pharmaceutical companies

Drug Discovery Today - Tập 17 - Trang 818-823 - 2012
Nicola Dimitri1,2,3
1Department of Economics and Statistics, University of Siena, Piazza S. Francesco 7, 53100 Siena, Italy
2Visiting Professor IMT Lucca, Lucca, Italy
3Research Associate Maastricht School of Management, Maastricht, Holland

Tài liệu tham khảo

Kremer, 2006 Glennerster, 2006, Creating markets for vaccines, Innovations, 1, 67, 10.1162/itgg.2006.1.1.67 Maurer, 2006, Choosing the right incentive strategy for research and development in neglected diseases, Bull. World Health Org., 84, 376, 10.2471/BLT.06.029835 Acemoglu, 2004, Market size in innovation: evidence from the pharmaceutical industry, Q. J. Econ., 119, 1049, 10.1162/0033553041502144 Booth, 2004, Prospects for productivity, Nat. Rev. Drug Discov., 3, 451, 10.1038/nrd1384 Paul, 2010, How to improve R&D productivity: the pharmaceutical industry's grand challenge, Nat. Rev. Drug Discov., 9, 203, 10.1038/nrd3078 Munos, 2009, Lessons from 60 years of pharmaceutical innovation, Nat. Rev. Drug Discov., 8, 959, 10.1038/nrd2961 Dimitri, 2011, What constitutes an optimal portfolio of pharmaceutical compounds?, Clin. Pharmacol. Ther., 89, 304, 10.1038/clpt.2010.247 Henderson, 2001, Scale and scope in drug development: unpacking the advantages of size in pharmaceutical research, J. Health Econ., 20, 1033, 10.1016/S0167-6296(01)00108-4 Ridley, 2006, Developing drugs for developing countries, Health Affairs, 25, 313, 10.1377/hlthaff.25.2.313 Dimitri, 2010, The economics of priority review vouchers, Drug Discov. Today, 15, 887, 10.1016/j.drudis.2010.08.008 Ridley, 2006, Introduction to European priority review vouchers to encourage development of new medicines for neglected diseases, The Lancet, 376, 1033 Osborne, 2004