Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase
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Akaboshi, 2014, Certain carotenoids enhance the intracellular glutathione level in a murine cultured macrophage cell line by inducing glutamate-cysteine-ligase, Mol. Nutr. Food Res., 58, 1291, 10.1002/mnfr.201300753
Awad, 2002, Identification of o-quinone/quinone methide metabolites of quercetin in a cellular in vitro system, FEBS Lett., 520, 30, 10.1016/S0014-5793(02)02754-0
Boersma, 2000, Regioselectivity and reversibility of the glutathione conjugation of quercetin quinone methide, Chem. Res. Toxicol., 13, 185, 10.1021/tx990161k
Boots, 2005, The reversibility of the glutathionyl-quercetin adduct spreads oxidized quercetin-induced toxicity, Biochem. Biophys. Res. Commun., 338, 923, 10.1016/j.bbrc.2005.10.031
Busu, 2014, Influence of GSH synthesis inhibition on temporal distribution of NAD+/NADH during vascular endothelial cells proliferation, J. Med. Life, 7, 611
Callegari, 2011, Gain and loss of function for glutathione synthesis: impact on advanced atherosclerosis in apolipoprotein E-deficient mice, Arterioscler. Thromb. Vasc. Biol., 31, 2473, 10.1161/ATVBAHA.111.229765
Canals, 2003, Nitric oxide triggers the toxicity due to glutathione depletion in midbrain cultures through 12-lipoxygenase, J. Biol. Chem., 278, 21542, 10.1074/jbc.M213174200
Chen, 2011, Nrf-2 mediated heme oxygenase-1 expression, an antioxidant-independent mechanism, contributes to anti-atherogenesis and vascular protective effects of Ginkgo biloba extract, Atherosclerosis, 214, 301, 10.1016/j.atherosclerosis.2010.11.010
Cole, 2014, Targeting multidrug resistance protein 1 (MRP1, ABCC1): past, present, And Future, Annu. Rev. Pharmacol. Toxicol., 54, 95, 10.1146/annurev-pharmtox-011613-135959
Costanzo, 2003, Endothelial activation by angiotensin II through NFkappaB and p38 pathways: Involvement of NFkappaB-inducible kinase (NIK), free oxygen radicals, and selective inhibition by aspirin, J. Cell Physiol., 195, 402, 10.1002/jcp.10191
Díaz-Hung, 2014, Sensory-motor performance after acute glutathione depletion by L-buthionine sulfoximine injection into substantia nigra pars compacta, Behav. Brain Res., 271, 286, 10.1016/j.bbr.2014.05.066
Förstermann, 2006, Endothelial nitric oxide synthase in vascular disease: from marvel to menace, Circulation, 113, 1708, 10.1161/CIRCULATIONAHA.105.602532
Huang, 2015, Obesity-Related Oxidative Stress: the Impact of Physical Activity and Diet Manipulation, Sports Med. Open, 1, 32, 10.1186/s40798-015-0031-y
Jenner, 2002, Vitamin C protects against hypochlorous Acid-induced glutathione depletion and DNA base and protein damage in human vascular smooth muscle cells, Arterioscler. Thromb. Vasc. Biol., 22, 574, 10.1161/01.ATV.0000013785.03265.5C
Kang, 2005, Molecular mechanism of nrf2 activation by oxidative stress, Antioxid. Redox Signal, 7, 1664, 10.1089/ars.2005.7.1664
Leslie, 2003, Bioflavonoid stimulation of glutathione transport by the 190-kDa multidrug resistance protein 1 (MRP1), Drug Metab. Dispos., 31, 11, 10.1124/dmd.31.1.11
Li, 2016, Quercetin inhibits LPS-induced adhesion molecule expression and oxidant production in human aortic endothelial cells by p38-mediated Nrf2 activation and antioxidant enzyme induction, Redox Biol., 10.1016/j.redox.2016.06.006
Lotito, 2011, Metabolic conversion of dietary flavonoids alters their anti-inflammatory and antioxidant properties, Free Radic. Biol. Med., 51, 454, 10.1016/j.freeradbiomed.2011.04.032
Lu, 2000, Regulation of glutathione synthesis, Curr. Top. Cell Regul., 36, 95, 10.1016/S0070-2137(01)80004-2
Lundgren, 1990, The metabolism of xenobiotics and its relationship to toxicity/genotoxicity: studies with human lymphocytes, Acta Physiol. Scand. Suppl., 592, 49
Minich, 2006, The multidrug resistance protein 1 (Mrp1), but not Mrp5, mediates export of glutathione and glutathione disulfide from brain astrocytes, J. Neurochem., 97, 373, 10.1111/j.1471-4159.2006.03737.x
Mueller, 2005, The role of the multidrug resistance protein-1 in modulation of endothelial cell oxidative stress, Circ. Res, 97, 637, 10.1161/01.RES.0000183734.21112.b7
Omar, 2014, The complex degradation and metabolism of quercetin in rat hepatocyte incubations, Xenobiotica, 44, 1074, 10.3109/00498254.2014.932032
Pamukcu, 2011, The nuclear factor – kappa B pathway in atherosclerosis: a potential therapeutic target for atherothrombotic vascular disease, Thromb. Res, 128, 117, 10.1016/j.thromres.2011.03.025
Park, 2006, Role of NADPH oxidase 4 in lipopolysaccharide-induced proinflammatory responses by human aortic endothelial cells, Cardiovasc. Res., 72, 447, 10.1016/j.cardiores.2006.09.012
Perticone, 2001, Obesity and body fat distribution induce endothelial dysfunction by oxidative stress: protective effect of vitamin C, Diabetes, 50, 159, 10.2337/diabetes.50.1.159
Pueyo, 2000, Angiotensin II stimulates endothelial vascular cell adhesion molecule-1 via nuclear factor-kappaB activation induced by intracellular oxidative stress, Arterioscler. Thromb. Vasc. Biol., 20, 645, 10.1161/01.ATV.20.3.645
Schafer, 2001, Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple, Free Radic. Biol. Med., 30, 1191, 10.1016/S0891-5849(01)00480-4
Smith, 2002, Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid, FASEB J., 16, 1102, 10.1096/fj.01-0825fje
Spencer, 2003, Intracellular metabolism and bioactivity of quercetin and its in vivo metabolites, Biochem. J., 372, 173, 10.1042/bj20021972
Townsend, 2003, The importance of glutathione in human disease, Biomed. Pharmacol., 57, 145, 10.1016/S0753-3322(03)00043-X
Tsukimori, 2005, Generation of reactive oxygen species by neutrophils and endothelial cell injury in normal and preeclamptic pregnancies, Hypertension, 46, 696, 10.1161/01.HYP.0000184197.11226.71
Tuleta, 2014, Hypoxia-induced endothelial dysfunction in apolipoprotein E-deficient mice; effects of infliximab and L-glutathione, Atherosclerosis, 236, 400, 10.1016/j.atherosclerosis.2014.08.021
Vargas, 2012, Cardiovascular and renal manifestations of glutathione depletion induced by buthionine sulfoximine, Am. J. Hypertens., 25, 629, 10.1038/ajh.2011.240
Wu, 2004, Glutathione metabolism and its implications for health, J. Nutr., 134, 489, 10.1093/jn/134.3.489
Zhang, 2010, Quercetin aglycone is bioavailable in murine pancreas and pancreatic xenografts, J. Agric. Food Chem., 58, 7252, 10.1021/jf101192k