Quantitative assessment of myelin basic protein-reactive T cell entry to the central nervous system by using oligonucleotide probes complementary to VDJ junctional sequences of rat TCR β-chain

Barbarese, 1992, Comparison of CNS homing pattern among murine TH cell lines responsive to myelin basic protein, J. Neuroimmunol., 39, 151, 10.1016/0165-5728(92)90184-M Baron, 1993, Surface expression of α4 integrin by CD4 T cells is required for their entry into brain parenchyma, J. Exp. Med., 177, 57, 10.1084/jem.177.1.57 Barten, 1995, Presence of T cells with activated and memory phenotypes in inflammatory spinal cord lesions, J. Immunol., 155, 5409, 10.4049/jimmunol.155.11.5409 Bell, 1993, Diverse T cell receptor Vβ gene usage in the central nervous system in experimental allergic encephalomyelitis, J. Immunol., 150, 4085, 10.4049/jimmunol.150.9.4085 Ben-Nun, 1981, The rapid isolation of clonable, antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis, Eur. J. Immunol., 11, 195, 10.1002/eji.1830110307 Caspi, 1989, Glial cells as suppressor cells: Characterization of the inhibitory function, J. Autoimmun., 2, 709, 10.1016/S0896-8411(89)80009-5 Cross, 1990, Homing to central nervous system vasculature by antigen-specific lymphocytes. I. Localization of 14C-labeled cells during acute, chronic and relapsing experimental allergic encephalomyelitis, Lab. Invest., 63, 162 Davis, 1988, T-cell antigen receptor genes and T-cell recognition, Nature, 334, 395, 10.1038/334395a0 Engel, 1988, Site-directed mutations in the VDJ junctional region of a T cell receptor beta chain cause changes in the antigenic peptide recognition, Cell, 54, 437, 10.1016/0092-8674(88)90068-2 Engelhardt, 1995, Lymphocytes infiltrating the CNS during inflammation display a distinct phenotype and bind to VCAM-1 but not to MAdCAM-1, Int. Immunol., 7, 481, 10.1093/intimm/7.3.481 Fontana, 1984, Astrocytes present myelin basic protein to encephalitogenic T-cell lines, Nature, 307, 273, 10.1038/307273a0 Gold, 1991, Analysis of T cell receptor β chains in Lewis rats with experimental allergic encephalomyelitis: Conserved complementarity determining region 3, J. Exp. Med., 174, 1467, 10.1084/jem.174.6.1467 Hedrick, 1984, Isolation of cDNA clones encoding T cell-specific membrane-associated proteins, Nature, 308, 149, 10.1038/308149a0 Hickey, 1991, Migration of hematogenous cells through the blood–brain barrier and the initiation of CNS inflammation, Brain Pathol., 1, 97, 10.1111/j.1750-3639.1991.tb00646.x Huang, 1991, A lymphocyte homing receptor (L-selectin) mediates the in vitro attachment of lymphocytes to myelinated tracts of the central nervous system, J. Clin. Invest., 88, 1778, 10.1172/JCI115498 Janzer, 1987, Astrocytes induce blood–brain barrier properties in endothelial cells, Nature, 325, 253, 10.1038/325253a0 Jones, 1992, The synthetic 87–99 peptide of myelin basic protein is encephalitogenic in Buffalo rats, J. Neuroimmunol., 37, 203, 10.1016/0165-5728(92)90004-5 Karlsson, 1992, An unusual class II molecule, Immunol. Today, 13, 469, 10.1016/0167-5699(92)90018-3 Körner, 1995, Unimpaired autoreactive T-cell traffic within the central nervous system during tumor necrosis factor receptor-mediated inhibition of experimental autoimmune encephalomyelitis, Proc. Natl. Acad. Sci. USA, 92, 11066, 10.1073/pnas.92.24.11066 Kronenberg, 1985, Rearrangement and transcription of the beta-chain genes of the T-cell antigen receptor in different types of murine lymphocytes, Nature, 313, 647, 10.1038/313647a0 Lannes Vieira, 1994, The inflammatory lesion of T cell line transferred experimental autoimmune encephalomyelitis of the Lewis rat: Distinct nature of parenchymal and perivascular infiltrates, Acta Neuropathol. Berl., 87, 435, 10.1007/BF00294169 Offner, 1989, T cell determinants of myelin basic protein include a unique encephalitogenic I–E-restricted epitope for Lewis rats, J. Exp. Med., 170, 355, 10.1084/jem.170.2.355 Oldstone, 1993, Trafficking of activated cytotoxic T lymphocytes into the central nervous system: Use of a transgenic model, J. Neuroimmunol., 46, 25, 10.1016/0165-5728(93)90230-V Skundric, 1993, Homing of T cells to the central nervous system throughout the course of relapsing experimental autoimmune encephalomyelitis in Thy-1 congenic mice, J. Neuroimmunol., 46, 113, 10.1016/0165-5728(93)90240-Y Smith, 1992, Vβ repertoire in rats and implications for endogenous superantigens, Eur. J. Immunol., 22, 641, 10.1002/eji.1830220305 Stepaniak, 1995, A comparative study of experimental autoimmune encephalomyelitis in Lewis and DA rats, J. Immunol., 155, 2762, 10.4049/jimmunol.155.5.2762 Sun, 1988, Up- and down-regulatory activities of astrocyte clones, Ann. N.Y. Acad. Sci., 430, 463, 10.1111/j.1749-6632.1988.tb27135.x Sun, 1988, Suppression of experimentally induced autoimmune encephalomyelitis by cytolytic T–T cell interactions, Nature, 332, 843, 10.1038/332843a0 Sun, 1992, Characterization of rat encephalitogenic T cells bearing non-Vβ8 T cell receptors, Eur. J. Immunol., 22, 591, 10.1002/eji.1830220244 Sun, 1993, Diverse T cell receptor β chain usage by rat encephalitogenic T cells reactive to residues 68–88 of myelin basic protein, Eur. J. Immunol., 23, 494, 10.1002/eji.1830230229 Sun, 1993, Major role of antigen-presenting cells in the response of rat encephalitogenic T cells to myelin basic proteins, J. Immunol., 151, 111, 10.4049/jimmunol.151.1.111 Sun, 1994, Characterization of brain-isolated rat encephalitogenic T cell lines, Eur. J. Immunol., 24, 1359, 10.1002/eji.1830240618 Sun, 1994, Repertoire of rat MBP-reactive T cells: DNA sequencing analysis further demonstrates the clonal heterogeneity of rat T cells reactive against encephalitogenic epitopes, Cell. Immunol., 156, 389, 10.1006/cimm.1994.1184 Sun, 1995, Heterogeneity of rat encephalitogenic T cells elicited by variants of the MBP(68–88) peptide, Eur. J. Immunol., 25, 1687, 10.1002/eji.1830250631 Sun, 1995, The clonal composition of myelin basic protein-reactive encephalitogenic T cell populations is influenced both by the structure of relevant antigens and the nature of antigen-presenting cells, Eur. J. Immunol., 25, 69, 10.1002/eji.1830250114 Sun, 1986, Ia-restricted encephalitogenic T lymphocytes mediating EAE lyse autoantigen-presenting astrocytes, Nature, 320, 70, 10.1038/320070a0 Toyonaga, 1984, Rearrangements of T-cell receptor gene YT35 in human DNA from thymic leukemia T-cell lines and functional T-cell clones, Nature, 311, 385, 10.1038/311385a0 Wekerle, 1986, Cellular immune reactivity within the CNS, Trends Neurosci., 9, 271, 10.1016/0166-2236(86)90077-9 Wekerle, 1987, Immune reactivity in the nervous system: Modulation of T lymphocyte activation by glial cells, J. Exp. Biol., 132, 43, 10.1242/jeb.132.1.43