Quantitative assessment of central β1 and β2-adrenoceptor regulation using CGP 20712 A

Baldwin, 1983, β1-Selective adrenoceptor antagonists: examples of the 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazole class, J Meet Chem, 26, 950 Dooley, 1983, Subchronic infusion of clenbuterol, a β-adrenergic agonist, decreases the cerebellar β receptor, Neurosci Lett, 36, 93, 10.1016/0304-3940(83)90492-5 Dooley, 1986, CCP 20712 A: a useful tool for quantitating β1- and β2- adrenoceptors, Eur J Pharmacol, 10.1016/0014-2999(86)90193-7 Dooley, 1983, Alteration of central α2-and β-adrenergic receptors in the rat after DSP-4, a selective noradrenergic neurotoxin, Neuroscience, 9, 889, 10.1016/0306-4522(83)90277-4 Dooley, 1983, Differential decrease of the central β-adrenergic receptor in the rat after subchronic infusion of desipramine and clenbuterol, Neurochem Int., 5, 333, 10.1016/0197-0186(83)90036-0 Goldstein, 1964, Biostatistics: An Introductory Text, 59 Kaumann, 1986, The β1-adrenoceptor antagonist CGP 20712 A unmasks β2-adrenoceptors activated by (−)-adrenaline in rat sinoatrial node, Naunyn Schmiedebergs Arch Pharmacol, 332, 406, 10.1007/BF00500096 Lowry, 1951, Protein measurement with the Folin phenol reagent, J Biol Chem, 193, 265, 10.1016/S0021-9258(19)52451-6 Macchia, 1985, An interdisciplinary approach to the design of new structures active at the β-adrenergic receptor. Aliphatic oxime ether derivatives, J Med Chem, 28, 153, 10.1021/jm00380a001 Minneman, 1983, Peripheral catecholamine administration does not alter cerebral β-adrenergic receptor density, Brain Res, 264, 328, 10.1016/0006-8993(83)90835-1 Minneman, 1979, β1-and β2-Adrenergic receptors in rat cerebral cortex are independently regulated, Science, 204, 866, 10.1126/science.35829 Minneman, 1979, Simultaneous determination of β1- and β2-adrenergic receptors in tissues containing both receptor subtypes, Mol Pharmacol, 16, 34 Pittman, 1980, Ontogeny of β1 and β2-adrenergic receptors in rat cerebellum and cerebral cortex, Brain Res, 188, 357, 10.1016/0006-8993(80)90037-2 Scatchard, 1949, The attractions of proteins for small molecules and ions, Ann NY Acad Sci, 51, 660, 10.1111/j.1749-6632.1949.tb27297.x Stiles, 1983, Mammalian β-adrenergic receptors: structural differences in β1- and β2-subtypes revealed by peptide map, J Biol Chem, 258, 10689, 10.1016/S0021-9258(17)44511-X Waldmeier, 1979, CGP 6085 A, a new specific inhibitor of serotonin uptake: neurochemical characterization and comparison with other serotonin uptake blockers, J Pharmacol Exp Ther, 211, 42