Quantitative analysis of PPARδ mRNA by real-time RT-PCR in 86 rectal cancer tissues

Kliewer, 1994, Differential expression and activation of a family of murine peroxisome proliferator-activated receptors, PNAS, 91, 7355, 10.1073/pnas.91.15.7355 Willson, 2000, The PPARs: from orphan receptors to drug discovery, J Med Chem, 43, 527, 10.1021/jm990554g Kliewer, 1999, The PPARs and RXRs: nuclear xenobiotic receptors that define novel hormone signaling pathways, Recent Prog Horm Res, 54, 345 Peters, 1997, Role of PPARΔalpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643, Carcinogenesis, 18, 2029, 10.1093/carcin/18.11.2029 Tontonoz, 1997, Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor γ and the retinoid X receptor, PNAS, 94, 237, 10.1073/pnas.94.1.237 Mueller, 1998, Terminal differentiation of human breast cancer through PPARΔgamma, Mol Cell, 1, 465, 10.1016/S1097-2765(00)80047-7 Sarraf, 1998, Differentiation and reversal of malignant changes in colon cancer through PPARΔgamma, Nat Med, 4, 1046, 10.1038/2030 Oliver, 2001, A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport, PNAS, 98, 5306, 10.1073/pnas.091021198 Barak, 2002, Effects of peroxisome proliferator-activated receptor δ on placentation, adiposity, and colorectal cancer, PNAS, 99, 303, 10.1073/pnas.012610299 He, 1999, PPARδ is an APC-regulated target of nonsteroidal anti-inflammatory drugs, Cell, 99, 335, 10.1016/S0092-8674(00)81664-5 Powell, 1992, APC mutations occur early during colorectal tumorigenesis, Nature, 359, 235, 10.1038/359235a0 Jörg, 2000, The Wnt signalling pathway, J Cell Sci, 113, 3545, 10.1242/jcs.113.20.3545 Gupta, 2000, Prostacyclin-mediated activation of peroxisome proliferator-activated receptorδ in colorectal cancer, PNAS, 97, 13275, 10.1073/pnas.97.24.13275 Roy, 2001, Distal bowel selectivity in the chemoprevention of experimental colon carcinogenesis by the non-steroidal anti-inflammatory drug nabumetone, Int J Cancer, 92, 609, 10.1002/ijc.1226 Bieche, 1999, Real-time reverse transcription-PCR assay for future management of ERBB2-based clinical applications, Clin Chem, 45, 1148, 10.1093/clinchem/45.8.1148 David, 2002, Gene quantification using real-time quantitative PCR: an emerging technology hits the mainstream, Exp Hematol, 30, 503, 10.1016/S0301-472X(02)00806-8 Michael, 2001, A new mathematical model for relative quantification in real-time RT-PCR, Nucleic Acids Res, 29, 2002 Mygind, 2002, Determination of PCR efficiency in chelex-100 purified clinical samples and comparison of real-time quantitative PCR and conventional PCR for detection of Chlamydia pneumoniae, BMC Microbiol, 2, 17, 10.1186/1471-2180-2-17 Michael, 2002, Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR, Nucleic Acids Res, 30, e36, 10.1093/nar/30.9.e36 Manly, 1997 Horgan, 2000, Introduction to randomisation tests Ben, 2001, Genetic disruption of PPARδ decreases the tumorigenicity of human colon cancer cells, PNAS, 98, 2598, 10.1073/pnas.051630998 Barak, 2002, Effects of peroxisome proliferator-activated receptorδ on placentation, adiposity, and colorectal cancer, PNAS, 99, 303, 10.1073/pnas.012610299 Marin, 1997, Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC, Science, 275, 1787, 10.1126/science.275.5307.1787 Jinyi, 2002, Peroxisome proliferator-activated receptors modulate K-ras-mediated transformation of intestinal epithelial cells, Cancer Res, 62, 3282