Quadruplex-Interactive Agents as Telomerase Inhibitors: Synthesis of Porphyrins and Structure−Activity Relationship for the Inhibition of Telomerase

Journal of Medicinal Chemistry - Tập 44 Số 26 - Trang 4509-4523 - 2001
Dong‐Fang Shi1, Richard T. Wheelhouse1, Daekyu Sun1, Laurence H. Hurley1
1College of Pharmacy, University of Texas at Austin, Austin, Texas 78712, The School of Pharmacy, The University of Bradford, Bradford BD7 1DP, United Kingdom, Institute for Drug Development, 14960 Omicron Drive, San Antonio, Texas 78245, Arizona Cancer Center, 1515 North Campbell Avenue, Tucson, Arizona 85724, and College of Pharmacy, The University of Arizona, Tucson, Arizona 85721

Tóm tắt

Từ khóa


Tài liệu tham khảo

Han H., 2000, Trends Pharmacol. Sci., 21, 142, 10.1016/S0165-6147(00)01448-6

Hurley L. H., 2000, Pharmacol. Ther., 85, 158, 10.1016/S0163-7258(99)00068-6

Kerwin S. M, 2000, Curr. Pharm. Des., 6, 471, 10.2174/1381612003400849

Jenkins T. C, 2000, Curr. Med. Chem., 7, 115, 10.2174/0929867003375551

Mergny J.-L., 1998, Nat. Med., 4, 1367

Raymond E., 1996, Curr. Opin. Biotechnol., 7, 591, 10.1016/S0958-1669(96)80068-1

Kelland L. R., 2001, Lancet, 2, 102, 10.1016/S1470-2045(00)00227-8

Bearss D. J., 2000, Oncogene, 19, 6641

Simonsson T., 1998, Nucleic Acids Res., 26, 1172, 10.1093/nar/26.5.1167

Castasi P., 1996, J. Mol. Biol., 264, 545

Usdin K., 1995, Nucleic Acids Res., 23, 4209, 10.1093/nar/23.20.4202

Smith S. S., 1994, J. Mol. Biol., 243, 150, 10.1006/jmbi.1994.1640

Freudenreich C. H., 1998, Science, 279, 856, 10.1126/science.279.5352.853

Oliver A. W., 2000, J. Mol. Biol., 301, 584, 10.1006/jmbi.2000.3991

Harrington C., 1997, J. Biol. Chem., 272, 24636

Fang G. W., 1993, Cell, 74, 885

Gilson E., 1993, J. Mol. Biol., 231, 310, 10.1006/jmbi.1993.1283

Kim N. W., 1994, Science, 266, 2015, 10.1126/science.7801130

Hahn W. C., 1999, Nat. Med., 5, 1170

de Lange T., 1999, Cell, 96, 275

Olovnikov A. M, 1973, J. Theor. Biol., 41, 190, 10.1016/0022-5193(73)90198-7

Makarov V. L., 1997, Cell, 88, 666, 10.1016/S0092-8674(00)81908-X

Zahler A. M., 1991, Nature, 350, 720, 10.1038/350718a0

Sun D., 1997, J. Med. Chem., 40, 2116

Wheelhouse R. T., 1998, J. Am. Chem. Soc., 120, 3262, 10.1021/ja973792e

Perry P. J., 1999, Exp. Opin. Invest. Drugs, 8, 2008

Izbicka E., 1999, Cancer Res., 59, 644

Chen Q., 1996, Proc. Natl. Acad. Sci. U.S.A., 93, 2639

Perry P. J., 1999, J. Med. Chem., 42, 2684, 10.1021/jm990084q

Perry P. J., 1999, Anti-Cancer Drug Des., 14, 382

Fedoroff O. Y., 1998, Biochemistry, 37, 12374, 10.1021/bi981330n

Guo Q., 1992, Biochemistry, 31, 2455, 10.1021/bi00124a003

Koeppel F., 2001, Nucleic Acids Res., 29, 1096, 10.1093/nar/29.5.1087

Gowan S. M., 2001, Proc. Am. Assoc. Cancer Res., 42, 466

Riou J.-F., 2001, Proc. Am. Assoc. Cancer Res., 42, 4496

Wheelhouse R. T., 1998, International Publication WO 98/33503

Lipscomb L. A., 1996, Biochemistry, 35, 2823, 10.1021/bi952443z

Guliaev A. B., 1999, Biochemistry, 38, 15437, 10.1021/bi9913808

Anantha N. A., 1998, Biochemistry, 37, 2714, 10.1021/bi973009v

Wang Y., 1993, Structure, 1, 282, 10.1016/0969-2126(93)90015-9

Han H., 2001, J. Am. Chem. Soc., 123, 6495

Han F. X., 1999, J. Am. Chem. Soc., 121, 3570

Haq I., 1999, J. Am. Chem. Soc., 121, 1779

Adler A. D., 1967, J. Org. Chem., 32, 476, 10.1021/jo01288a053

Gunter M. J., 1981, J. Org. Chem., 46, 4795, 10.1021/jo00336a037

Ackerley N., 1995, J. Med. Chem., 38, 1628, 10.1021/jm00010a005

Million M.-E., 1996, Anti-Cancer Drug Des., 11, 153

Snyder S. E., 1995, J. Med. Chem., 38, 2409

Clezy P. S., 1969, Aust. J. Chem., 22, 249, 10.1071/CH9690239

Chong R., 1969, Aust. J. Chem., 22, 238, 10.1071/CH9690229

Mankra J. S., 1989, Tetrahedron Lett., 30, 6992

Dancil K.-P. S., 1997, J. Heterocycl. Chem., 34, 755

Sun D., 1998, BioTechniques, 25, 1051

Han H., 1999, Biochemistry, 38, 6986

Cauzzo G., 1977, Photochem. Photobiol., 25, 395, 10.1111/j.1751-1097.1977.tb07358.x

Georgiou G. N., 1994, Photochem. Photobiol., 59, 422, 10.1111/j.1751-1097.1994.tb05058.x

Villanueva A., 1993, Cancer Lett., 73, 64, 10.1016/0304-3835(93)90188-F

Izbicka E., 1999, Anti-Cancer Drug Des., 14, 365

Still W. C., 1978, J. Org. Chem., 43, 2925, 10.1021/jo00408a041

Matsushima Y., 1980, Chem. Pharm. Bull., 28, 2675, 10.1248/cpb.28.2672

Boschelli D. H., 1995, J. Med. Chem., 38, 4614, 10.1021/jm00022a026