Purification of Human CD34+CD90+ HSCs Reduces Target Cell Population and Improves Lentiviral Transduction for Gene Therapy

Molecular Therapy - Methods & Clinical Development - Tập 18 - Trang 679-691 - 2020
Stefan Radtke1,2, Dnyanada Pande1,2, Margaret Cui1,2, Anai M. Perez1,2, Yan-Yi Chan1,2, Mark Enstrom1,2, Stefanie Schmuck1,2, Andrew Berger2, Tom Eunson2, Jennifer E. Adair1,2,3, Hans-Peter Kiem1,2,4,5
1Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
2Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
3Department of Medical Oncology, University of Washington School of Medicine, Seattle, WA 98195, USA
4Department of Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA
5Department of Pathology, University of Washington School of Medicine, Seattle, WA 98195, USA

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