Pulsatile crossflow improves microfiltration fractionation of cells and proteins

Saxena, 2009, Membrane-based techniques for the separation and purification of proteins: an overview, Adv. Colloid Interface Sci., 145, 1, 10.1016/j.cis.2008.07.004 van Reis, 2007, Bioprocess membrane technology, J. Membr. Sci., 297, 16, 10.1016/j.memsci.2007.02.045 Fane, 2009, Fouling in membrane processes, 121 Foley, 2006, A review of factors affecting filter cake properties in dead-end microfiltration of microbial suspensions, J. Membr. Sci., 274, 38, 10.1016/j.memsci.2005.12.008 Zhang, 2015, A review on flux decline control strategies in pressure-driven membrane processes, Ind. Eng. Chem. Res., 54, 2843, 10.1021/ie504848m Kuberkar, 1999, Effects of added yeast on protein transmission and flux in cross-flow membrane microfiltration, Biotechnol. Prog., 15, 472, 10.1021/bp990023l Patel, 1987, Cross-flow membrane filtration of yeast suspensions, J. Biotechnol., 5, 1, 10.1016/0168-1656(87)90066-6 Auddy, 2004, Flux enhancement in nanofiltration of dye solution using turbulent promoters, Separ. Purif. Technol., 40, 31, 10.1016/j.seppur.2004.01.001 Armbruster, 2018, Fouling mitigation in tubular membranes by 3D-printed turbulence promoters, J. Membr. Sci., 554, 156, 10.1016/j.memsci.2018.02.015 Armbruster, 2020, Short and spaced twisted tapes to mitigate fouling in tubular membranes, J. Membr. Sci., 595, 117426, 10.1016/j.memsci.2019.117426 Beier, 2006, Dynamic microfiltration with a vibrating hollow fiber membrane module: filtration of yeast suspensions, J. Membr. Sci., 281, 281, 10.1016/j.memsci.2006.03.051 Matsumoto, 1996, Improvement of membrane permeation performance by ultrasonic microfiltration, J. Chem. Eng. Jpn., 29, 561, 10.1252/jcej.29.561 Matsumoto, 1987, Separation of yeast by cross-flow filtration with backwashing, J. Ferment. Technol., 65, 77, 10.1016/0385-6380(87)90068-9 Matsumoto, 1988, Cross-flow filtration of yeast by microporous ceramic membrane with backwashing, J. Ferment. Technol., 66, 199, 10.1016/0385-6380(88)90048-9 Jaffrin, 2012, Hydrodynamic techniques to enhance membrane filtration, Annu. Rev. Fluid Mech., 44, 77, 10.1146/annurev-fluid-120710-101112 Bertram, 1993, Flux enhancement in crossflow microfiltration using a collapsible-tube pulsation generator, J. Membr. Sci., 84, 279, 10.1016/0376-7388(93)80023-Q Hadzismajlovic, 1999, Flux enhancement in turbulent crossflow microfiltration of yeast using a collapsible-tube pulsation generator, J. Membr. Sci., 163, 123, 10.1016/S0376-7388(99)00161-1 Curcio, 2002, Monitoring and control of TMP and feed flow rate pulsatile operations during ultrafiltration in a membrane module, Desalination, 145, 217, 10.1016/S0011-9164(02)00415-0 Gillham, 2000, Enhanced cleaning of whey protein soils using pulsed flows, J. Food Eng., 46, 199, 10.1016/S0260-8774(00)00083-2 Gupta, 1992, Permeate flux enhancement by pressure and flow pulsations in microfiltration with mineral membranes, J. Membr. Sci., 70, 257, 10.1016/0376-7388(92)80111-V Weinberger, 2021, Effect of low-frequency pulsatile crossflow microfiltration on flux and protein transmission in milk protein fractionation, Separ. Sci. Technol., 56, 1112, 10.1080/01496395.2020.1749080 Olayiwola, 2009, Effects of in-phase oscillation of retentate and filtrate in crossflow filtration at low Reynolds number, J. Membr. Sci., 345, 36, 10.1016/j.memsci.2009.08.022 Mezger, 2020 Blel, 2009, Application of turbulent pulsating flows to the bacterial removal during a cleaning in place procedure. Part 1: experimental analysis of wall shear stress in a cylindrical pipe, J. Food Eng., 90, 422, 10.1016/j.jfoodeng.2008.07.008 Altmann, 1997, Particle deposition and layer formation at the crossflow microfiltration, J. Membr. Sci., 124, 119, 10.1016/S0376-7388(96)00235-9 Kovaleva, 2017, Effect of transmembrane pressure on microfiltration concentration of yeast biomass, Petrol. Chem., 57, 974, 10.1134/S0965544117110044 Redkar, 1993, Crossflow microfiltration of yeast suspensions in tubular filters, Biotechnol. Prog., 9, 625, 10.1021/bp00024a009 Wang, 2009, The influence of various operating conditions on specific cake resistance in the crossflow microfiltration of yeast suspensions, Desalination and Water Treatment, 1, 237, 10.5004/dwt.2009.124 Hughes, 2006, Crossflow filtration of washed and unwashed yeast suspensions at constant shear under nominally sub-critical conditions, J. Membr. Sci., 280, 89, 10.1016/j.memsci.2006.01.022 Keskinler, 2004, Crossflow microfiltration of low concentration-nonliving yeast suspensions, J. Membr. Sci., 233, 59, 10.1016/j.memsci.2003.12.014 Mota, 2002, Influence of cell-shape on the cake resistance in dead-end and cross-flow filtrations, Separ. Purif. Technol., 27, 137, 10.1016/S1383-5866(01)00202-7 Tanaka, 1997, Characteristics in crossflow filtration using different yeast suspensions, Separ. Sci. Technol., 32, 1885, 10.1080/01496399708000743 Ye, 2005, Reversibility of heterogeneous deposits formed from yeast and proteins during microfiltration, J. Membr. Sci., 265, 20, 10.1016/j.memsci.2005.04.031 Foley, 1992, Preferential deposition of smaller cells during cross-flow microfiltration of a yeast suspension, Biotechnol. Tech., 6, 115, 10.1007/BF02438815 Ben Hassan, 2013, Experimental study of membrane fouling during crossflow microfiltration of yeast and bacteria suspensions: towards an analysis at the microscopic level, Membranes, 3, 44, 10.3390/membranes3020044 McCarthy, 1999, Characterisation of cake compressibility in dead-end microfiltration of microbial suspensions, Chem. Eng. Commun., 173, 79, 10.1080/00986449908912777 Kuberkar, 2001, Microfiltration of protein-cell mixtures with crossflushing or backflushing, J. Membr. Sci., 183, 1, 10.1016/S0376-7388(00)00577-9 Shouren, 1998, Bovine serum albumin adsorption onto immobilized organotrichlorosilane surface: influence of the phase separation on protein adsorption patterns, J. Biomater. Sci. Polym. Ed., 9, 131, 10.1163/156856298X00479 Dumpler, 2017, Dissociation and coagulation of caseins and whey proteins in concentrated skim milk heated by direct steam injection, Dairy Sci. Technol., 96, 807, 10.1007/s13594-016-0304-3 Schopf, 2020, Impact of hollow fiber membrane length on the milk protein fractionation, J. Membr. Sci., 118834 Piry, 2008, Length dependency of flux and protein permeation in crossflow microfiltration of skimmed milk, J. Membr. Sci., 325, 887, 10.1016/j.memsci.2008.09.025 Ho, 2002, Transmembrane pressure profiles during constant flux microfiltration of bovine serum albumin, J. Membr. Sci., 209, 363, 10.1016/S0376-7388(02)00282-X Schiffer, 2020, On the reversibility of deposit formation in low temperature milk microfiltration with ceramic membranes depending on mode of adjustment of transmembrane pressure and wall shear stress, Separ. Purif. Technol., 247, 116962, 10.1016/j.seppur.2020.116962 Howell, 1993, Yeast cell microfiltration: flux enhancement in baffled and pulsatile flow systems, J. Membr. Sci., 80, 59, 10.1016/0376-7388(93)85132-G Wu, 1993, Pulsatile flow filtration of yeast cell debris: influence of preincubation on performance, Biotechnol. Bioeng., 41, 998, 10.1002/bit.260411011 Curcio, 2005, Ultrafiltration of BSA in pulsating conditions: an artificial neural networks approach, J. Membr. Sci., 246, 235, 10.1016/j.memsci.2004.09.004 Hadzismajlovic, 1998, Flux enhancement in laminar crossflow microfiltration using a collapsible-tube pulsation generator, J. Membr. Sci., 142, 173, 10.1016/S0376-7388(97)00319-0 Shamel, 1999, Cross flow ultrafiltration studies on solutions of pectin with pulsatile flow insitu cleaning, artificial cells, blood substitutes, Biotechnology, 27, 447