Psychological factors associated with disseminated lupus erythematosus and effects of cortisone and ACTH

Psychiatric Quarterly - Tập 30 - Trang 44-60 - 1956
Selwyn Brody1
1New York 28

Tóm tắt

A study of the psychological development, symptomatology and course of 42 patients who were suffering from the disease process known clinically as disseminated lupus erythematosus confirms the finding that the disease is primarily one occurring in young female individuals. The disease frequently has a fatal outcome, as indicated by the fact that 11 of the 42 patients whose cases were studied died from the illness. Psychological stress situations appeared to have been a consistent etiological factor in the precipitation of the disease outbreak, recurrence or exacerbation. Favorable psychological influence appeared to mitigate the disease course. The development of a sustained psychosis or of an alternating trend between psychosis and organic symptoms appeared to have a therapeutic effect and served to prevent a fatal outcome. It is suggested that an important factor in determining the outcome of disseminated lupus erythematosus, and even possibly the etiology of the disease, is to be found in the type of patterns of behavior with which the ego is built during the first two years of life. The investigation of this possibility requires careful study of disseminated lupus patients while they are receiving corrective analytic psychotherapy.

Tài liệu tham khảo

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