Protective effects of sinomenine against dextran sulfate sodium-induced ulcerative colitis in rats via alteration of HO-1/Nrf2 and inflammatory pathway

Zhongbao Niu1, Xinhong Li2, Xiuhua Yang3, Zhongwei Sun4
1Department of Traditional Chinese Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China
2Department of Outpatient Surgery, Central Hospital Affiliated to Shandong First Medical University, No. 105 Jiefang Road, Jinan, 250013, Jinan, China
3Department of Gastroenterology, Central Hospital Affiliated to Shandong First Medical University, No. 105 Jiefang Road, Jinan, 250013, Jinan, China
4Department of Gastrointestinal Surgery, Jinan Central Hospital, No.105, Jiefang Road, Lixia District, Jinan, 250013, Shandong, China

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