Proteasome Function and Protein Oxidation in the Aged Retina

Agarwal, 1994, Aging and proteolysis of oxidized proteins, Arch. Biochem. Biophys, 309, 26, 10.1006/abbi.1994.1078 Andersson, 1998, Proteolytic cleavage of N-Suc-Leu-Leu-Val-Tyr-AMC by the proteasome in lens epithelium from clear and cataractous human lenses, Exp. Eye Res, 67, 231, 10.1006/exer.1998.0519 Anselmi, 1998, Dietary self-selection can compensate an age-related decrease of rat liver 20S proteasome activity observed with standard diet, J. Gerontol. A Biol. Sci. Med. Sci, 53, B173, 10.1093/gerona/53A.3.B173 Bardag-Gorce, 1999, Changes in 20S protesome activity during aging of the LOU rat, Molec. Biol. Rep, 26, 89, 10.1023/A:1006968208077 Beatty, 2000, The role of oxidative stress in the pathogenesis of age-related macular degeneration, Surv. Ophthalmol, 45, 115, 10.1016/S0039-6257(00)00140-5 Boscia, 2000, Protein oxidation and lens opacity in humans, Invest. Ophthalmol. Vis. Sci, 41, 2461 Brooks, 2001, Reduced severity of oxygen-induced retinopathy in eNOS-deficient mice, Invest. Ophthalmol. Vis. Sci, 42, 222 Bulteau, 2000, Age-related alterations of proteasome structure and function in aging epidermis, Exp. Gerontol, 35, 767, 10.1016/S0531-5565(00)00136-4 Cai, 2000, Oxidative damage and protection of the RPE, Prog. Retin Eye Res, 19, 205, 10.1016/S1350-9462(99)00009-9 Carney, 1991, Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone, Proc. Nat. Acad. Sci, 88, 3633, 10.1073/pnas.88.9.3633 Chen, 1996, Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assembly, Cell, 86, 961, 10.1016/S0092-8674(00)80171-3 Chondrogianni, 2000, Fibroblast cultures from healthy centenarians have an active proteasome, Exp. Gerontol, 35, 721, 10.1016/S0531-5565(00)00137-6 Conconi, 1997, Proteasome inactivation upon aging and on oxidation-effect of HSP 90, Molec. Biol. Rep, 24, 45, 10.1023/A:1006852506884 Craui, 1997, Lactacystin and clasto-Lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation, J. Biol. Chem, 272, 13437, 10.1074/jbc.272.20.13437 Davies, 2001, Degradation of oxidized proteins by the 20S proteasome, Biochimie, 83, 301, 10.1016/S0300-9084(01)01250-0 Davies, 1997 DeMartino, 1996, Identification, purification, and characterization of a PA700-dependent activator of the proteasome, J. Biol. Chem, 271, 3112, 10.1074/jbc.271.6.3112 Ehring, 1996, Effects of major histocompatibility-complex-encoded subunits of the peptidase and proteolytic activities of human 20S proteasomes, Eur. J. Biochem, 235, 404, 10.1111/j.1432-1033.1996.00404.x Esterbauer, 1985, Metabolism of the lipid peroxidation product 4-hydroxynonenal by isolated hepatocytes and by liver cytosolic fractions, Biochem. J, 228, 363, 10.1042/bj2280363 Fenteany, 1995, Inhibition of proteasome activities and subunit-specific amino terminal threonine modification by lactacysin, Science, 268, 726, 10.1126/science.7732382 Ferrington, 2001, Selective degradation of oxidized calmodulin by the 20S proteasome, J. Biol. Chem, 276, 937, 10.1074/jbc.M005356200 Fliesler, 1983, Chemistry and metabolism of lipids in the vertebrate retina, Prog. Lipid Res, 22, 79, 10.1016/0163-7827(83)90004-8 Friguet, 1997, Inhibition of the muticatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein, FEBS Lett, 405, 21, 10.1016/S0014-5793(97)00148-8 Groll, 1997, Structure of the 20S proteasome from yeast at 2.4 Å resolution, Nature, 386, 463, 10.1038/386463a0 Harding, 1997 Hayashi, 1998, Age-related changes in the 20S and 26S proteasome activities in the liver of male F344 rats, Mech. Ageing Dev, 102, 55, 10.1016/S0047-6374(98)00011-6 Hochstrasser, 1996, Ubiquitin-dependent protein degradation, Genetics, 30, 405, 10.1146/annurev.genet.30.1.405 Ischiropoulos, 1992, Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase, Arch. Biochem. Biophys, 298, 431, 10.1016/0003-9861(92)90431-U Ishibashi, 1998, Advanced glycation end products in age-related macular degeneration, Arch. Ophthalmol, 116, 1629, 10.1001/archopht.116.12.1629 Kassoff, 2001, A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degradation and vision loss, Arch. Ophthalmol, 119, 1417, 10.1001/archopht.119.10.1417 Keller, 2000, Impaired proteasome function in Alzheimer's disease, J. Neurochem, 75, 436, 10.1046/j.1471-4159.2000.0750436.x Keller, 2000, Possible involvement of proteasome inhibition in aging: implications for oxidative stress, Mech. Ageing Dev, 113, 61, 10.1016/S0047-6374(99)00101-3 Keller, 2000, Decreased levels of proteasome activity and proteasome expression in aging spinal cord, Neuroscience, 98, 149, 10.1016/S0306-4522(00)00067-1 Khan, 2001, Characterization of membrane-associated proteasomes in WB rat liver epithelial cells, Arch. Biochem. Biophys, 385, 99, 10.1006/abbi.2000.2116 Kisselev, 1999, The size of peptides generated from protein by mammalian 26S and 20S proteasome. Implications for understanding the degradative mechanism and antigen presentation, J. Biol. Chem, 274, 3363, 10.1074/jbc.274.6.3363 Kliffen, 1995, Protein analysis of human maculae in relation to age-related maculopathy, Lab. Invest, 73, 267 Köhler, 2001, The substrate translocation channel of the proteasome, Biochemie, 83, 325, 10.1016/S0300-9084(01)01242-1 Laemmli, 1970, Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature, 227, 680, 10.1038/227680a0 Lee, 1996, Selective inhibitors of the proteasome-dependent and vacuolar pathways of protein degeneration in Saccharomyces cerevisiae, J. Biol. Chem, 271, 27280, 10.1074/jbc.271.44.27280 Miyagi, 2002, Evidence that light modulates protein nitration in rat retina, Molec. Cell. Proteomics, 1, 293, 10.1074/mcp.M100034-MCP200 Nelson, 2000, Proteasome from cytokine-treated human cells shows stimulated BrAAP activity and depressed PGPH activity, Biochem. Cell Biol, 78, 115, 10.1139/o00-006 Neufeld, 1999, Nitric oxide: a potential mediator of retinal ganglion cell damage in glaucoma, Surv. Ophthalmol, 43, 129, 10.1016/S0039-6257(99)00010-7 Okada, 1999, 4-hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules, J. Biol. Chem, 274, 23787, 10.1074/jbc.274.34.23787 Petropoulus, 2000, Increase of oxidatively modified protein is associated with a decrease of proteasome activity and content in aging epidermal cells, J. Gerontol. A Biol. Sci. Med. Sci, 55, B220, 10.1093/gerona/55.5.B220 Pratico, 2000, Oxidative injury in diseases of the central nervous system: focus on Alzheimer's disease, Am. J. Med, 109, 577, 10.1016/S0002-9343(00)00547-7 Ponnappan, 1999, Decreased proteasome-mediated degradation in T-cells for the elderly: a role in immune senescence, Cell. Immunol, 192, 167, 10.1006/cimm.1998.1418 Reidlinger, 1997, Catalytic properties of 26S and 20S proteasomes and radiolabelling of MB1, LMP7, and C7 subunits associated with trypsin-like and chymotrypsin-like activities, J. Biol. Chem, 272, 24899, 10.1074/jbc.272.40.24899 Reinheckel, 1998, Comparative resistance of the 20S and 26S proteasome to oxidative stress, Biochem. J, 335, 637, 10.1042/bj3350637 Rock, 1994, Inhibitors of the proteasome block the degeneration of most cell proteins and the generation of peptides presented on MHC class I molecules, Cell, 78, 761, 10.1016/S0092-8674(94)90462-6 Sahakian, 1995, Aging of the liver: proteolysis of oxidatively modified glutamine synthetase, Arch. Biochem. Biophys, 318, 411, 10.1006/abbi.1995.1248 Sayre, 1999, In situ methods for detection and localization of markers of oxidative stress: applications in neurodegenerative disorders, Methods Enzymol, 309, 133, 10.1016/S0076-6879(99)09012-6 Shimizu, 1999, Stimulation of macrophages by retinal proteins: production of reactive nitrogen and oxygen metabolites, Invest. Ophthalmol. Sci, 40, 3215 Stadtman, 1992, Protein oxidation and aging, Science, 257, 1220, 10.1126/science.1355616 Starke-Reed, 1989, Protein oxidation and proteolysis during aging and oxidative stress, Arch. Biochem. Biophys, 275, 559, 10.1016/0003-9861(89)90402-5 Stolzing, 2001, The proteasome and its function in the ageing process, Clin. Exp. Dermatol, 26, 566, 10.1046/j.1365-2230.2001.00867.x Towbin, 1979, Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications, Proc. Nat. Acad. Sci. U.S.A, 76, 4350, 10.1073/pnas.76.9.4350 Verdejo, 1999, Lipid peroxidation in proliferative vitreoretinopathies, Eye, 13, 183, 10.1038/eye.1999.48 Voges, 1999, The 26S proteasome: a molecular machine designed for controlled proteolysis, Annu. Rev. Biochem, 68, 1015, 10.1146/annurev.biochem.68.1.1015 Wagner, 1995, Age-dependent association of isolated bovine lens multicatalytic proteinase complex (proteasome) and the heat shock protein 90, an endogenous inhibitor, Arch. Biochem. Biophys, 323, 455, 10.1006/abbi.1995.0067 Winkler, 1999, Oxidative damage and age-related macular degeneration, Mol. Vis, 5, 32