Prone ventilation reduces mortality in patients with acute respiratory failure and severe hypoxemia: systematic review and meta-analysis

Intensive Care Medicine - Tập 36 Số 4 - Trang 585-599 - 2010
Sachin Sud1, Jan O. Friedrich2,1, Paolo Taccone3, Federico Polli4, Neill K. J. Adhikari5,1, Roberto Latini6, Antonio Pesenti7,8, Claude Guérin9, Jordi Mancebo10, Martha A. Q. Curley11, Rafael Fernández12, Ming Cheng Chan13, Pascal Beuret14, G. Voggenreiter15, Maneesh Sud16, Gianni Tognoni17, Luciano Gattinoni3,4
1Interdepartmental Division of Critical Care, University of Toronto, Toronto, Canada
2Critical Care and Medicine Departments, The Keenen Research Centre in the Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Canada
3Dipartimento di Anestesia e Rianimazione, Fondazione IRCCS – “Ospedale Maggiore Policlinico, Mangiagalli, Regina Elena” di Milano, Milan, Italy
4Istituto di Anestesiologia e Rianimazione, Università degli Studi di Milano, Milan, Italy
5Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Sunnybrook Research Institute, Toronto, Canada
6Department of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
7Dipartimento di Medicina Perioperatoria e Terapie Intensive, Azienda Ospedaliera San Gerardo di Monza, Monza, Italy
8Dipartimento di Medicina Sperimentale, Università degli Studi Milano-Bicocca, Milan, Italy
9Service de Réanimation Médicale et Assistance Respiratoire, Hôpital de la Croix-Rousse, Lyon, France
10Servei de Medicina Intensiva, Hospital de Sant Pau, Barcelona, Spain
11School of Nursing, University of Pennsylvania, Philadelphia, USA
12ICU Department, CIBERES, Hospital Sant Joan de Deu-Fundacio Althaia, Manresa, Spain
13Section of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan
14Service de Réanimation, Centre Hospitalier, Roanne, France
15Department of Orthopaedic and Trauma Surgery, Hospitals in the Natureparc Altmühltal, Eichstätt, Germany
16Faculty of Medicine, University of Manitoba, Winnipeg, Canada
17Consorzio Mario Negri Sud, Santa Maria Imbaro, Italy

Tóm tắt

Từ khóa


Tài liệu tham khảo

Rubenfeld GD, Caldwell E, Peabody E, Weaver J, Martin DP, Neff M, Stern EJ, Hudson LD (2005) Incidence and outcomes of acute lung injury. N Engl J Med 353:1685–1693

Phua J, Badia JR, Adhikari NK, Friedrich JO, Fowler RA, Singh JM, Scales DC, Stather DR, Li A, Jones A, Gattas DJ, Hallett D, Tomlinson G, Stewart TE, Ferguson ND (2009) Has mortality from acute respiratory distress syndrome decreased over time? A systematic review. Am J Respir Crit Care Med 179:220–227

Herridge MS, Cheung AM, Tansey CM, Matte-Martyn A, Diaz-Granados N, Al-Saidi F, Cooper AB, Guest CB, Mazer CD, Mehta S, Stewart TE, Barr A, Cook D, Slutsky AS (2003) One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med 348:683–693

Angus DC, Musthafa AA, Clermont G, Griffin MF, Linde-Zwirble WT, Dremsizov TT, Pinsky MR (2001) Quality-adjusted survival in the first year after the acute respiratory distress syndrome. Am J Respir Crit Care Med 163:1389–1394

Cheung AM, Tansey CM, Tomlinson G, Diaz-Granados N, Matte A, Barr A, Mehta S, Mazer CD, Guest CB, Stewart TE, Al-Saidi F, Cooper AB, Cook D, Slutsky AS, Herridge MS (2006) Two-year outcomes, health care use, and costs of survivors of acute respiratory distress syndrome. Am J Respir Crit Care Med 174:538–544

Artigas A, Bernard GR, Carlet J, Dreyfuss D, Gattinoni L, Hudson L, Lamy M, Marini JJ, Matthay MA, Pinsky MR, Spragg R, Suter PM (1998) The American–European Consensus Conference on ARDS, part 2. Ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to recovery and remodeling. Acute respiratory distress syndrome. Am J Respir Crit Care Med 157:1332–1347

(2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 342:1301–1308

Bryan AC (1974) Conference on the scientific basis of respiratory therapy. Pulmonary physiotherapy in the pediatric age group. Comments of a devil’s advocate. Am Rev Respir Dis 110:143–144

Pelosi P, Brazzi L, Gattinoni L (2002) Prone position in acute respiratory distress syndrome. Eur Respir J 20:1017–1028

Gattinoni L, Pesenti A, Baglioni S, Vitale G, Rivolta M, Pelosi P (1988) Inflammatory pulmonary edema and positive end-expiratory pressure: correlations between imaging and physiologic studies. J Thorac Imaging 3:59–64

Gattinoni L, Pelosi P, Vitale G, Pesenti A, D’Andrea L, Mascheroni D (1991) Body position changes redistribute lung computed-tomographic density in patients with acute respiratory failure. Anesthesiology 74:15–23

Pappert D, Rossaint R, Slama K, Gruning T, Falke KJ (1994) Influence of positioning on ventilation–perfusion relationships in severe adult respiratory distress syndrome. Chest 106:1511–1516

Gillart T, Bazin JE, Guelon D, Constantin JM, Mansoor O, Conio N, Schoeffler P (2000) Effect of bronchial drainage on the improvement in gas exchange observed in ventral decubitus in ARDS (French). Ann Fr Anesth Reanim 19:156–163

Galiatsou E, Kostanti E, Svarna E, Kitsakos A, Koulouras V, Efremidis SC, Nakos G (2006) Prone position augments recruitment and prevents alveolar overinflation in acute lung injury. Am J Respir Crit Care Med 174:187–197

Gattinoni L, Protti A (2008) Ventilation in the prone position: for some but not for all? CMAJ 178:1174–1176

Gattinoni L, Tognoni G, Pesenti A, Taccone P, Mascheroni D, Labarta V, Malacrida R, Di Giulio P, Fumagalli R, Pelosi P, Brazzi L, Latini R (2001) Effect of prone positioning on the survival of patients with acute respiratory failure. N Engl J Med 345:568–573

Guerin C, Gaillard S, Lemasson S, Ayzac L, Girard R, Beuret P, Palmier B, Le QV, Sirodot M, Rosselli S, Cadiergue V, Sainty JM, Barbe P, Combourieu E, Debatty D, Rouffineau J, Ezingeard E, Millet O, Guelon D, Rodriguez L, Martin O, Renault A, Sibille JP, Kaidomar M (2004) Effects of systematic prone positioning in hypoxemic acute respiratory failure: a randomized controlled trial. JAMA 292:2379–2387

Mancebo J, Fernandez R, Blanch L, Rialp G, Gordo F, Ferrer M, Rodriguez F, Garro P, Ricart P, Vallverdu I, Gich I, Castano J, Saura P, Dominguez G, Bonet A, Albert RK (2006) A multicenter trial of prolonged prone ventilation in severe acute respiratory distress syndrome. Am J Respir Crit Care Med 173:1233–1239

Sud S, Sud M, Friedrich JO, Adhikari NK (2008) Effect of mechanical ventilation in the prone position on clinical outcomes in patients with acute hypoxemic respiratory failure: a systematic review and meta-analysis. CMAJ 178:1153–1161

Tiruvoipati R, Bangash M, Manktelow B, Peek GJ (2008) Efficacy of prone ventilation in adult patients with acute respiratory failure: a meta-analysis. J Crit Care 23:101–110

Alsaghir AH, Martin CM (2008) Effect of prone positioning in patients with acute respiratory distress syndrome: a meta-analysis. Crit Care Med 36:603–609

Kopterides P, Siempos II, Armaganidis A (2009) Prone positioning in hypoxemic respiratory failure: meta-analysis of randomized controlled trials. J Crit Care 24:89–100

Abroug F, Ouanes-Besbes L, Elatrous S, Brochard L (2008) The effect of prone positioning in acute respiratory distress syndrome or acute lung injury: a meta-analysis. Areas of uncertainty and recommendations for research. Intensive Care Med 34:1002–1011

Sud S, Sud M, Friedrich JO, Adhikari NK (2008) Effect of prone positioning in patients with acute respiratory distress syndrome and high Simplified Acute Physiology Score II. Crit Care Med 36:2711–2712 author reply 2712–2713

Leonet S, Fontaine C, Moraine JJ, Vincent JL (2002) Prone positioning in acute respiratory failure: survey of Belgian ICU nurses. Intensive Care Med 28:576–580

Gattinoni L, Caironi P, Cressoni M, Chiumello D, Ranieri VM, Quintel M, Russo S, Patroniti N, Cornejo R, Bugedo G (2006) Lung recruitment in patients with the acute respiratory distress syndrome. N Engl J Med 354:1775–1786

Taccone P, Pesenti A, Latini R, Polli F, Vagginelli F, Mietto C, Caspani L, Raimondi F, Bordone G, Iapichino G, Mancebo J, Guérin C, Ayzac L, Blanch L, Fumagalli R, Tognoni G, Gattinoni L (2009) Prone positioning in patients with moderate and severe acute respiratory distress syndrome: a randomized controlled trial. JAMA 302:1977–1984

Meade MO, Richardson WS (1997) Selecting and appraising studies for a systematic review. Ann Intern Med 127:531–537

Cook DJ, Guyatt GH, Ryan G, Clifton J, Buckingham L, Willan A, McIlroy W, Oxman AD (1993) Should unpublished data be included in meta-analyses? Current convictions and controversies. JAMA 269:2749–2753

Egger M, Zellweger-Zahner T, Schneider M, Junker C, Lengeler C, Antes G (1997) Language bias in randomised controlled trials published in English and German. Lancet 350:326–329

Berlin JA (1997) Does blinding of readers affect the results of meta-analyses? University of Pennsylvania Meta-analysis Blinding Study Group. Lancet 350:185–186

Schulz KF, Chalmers I, Hayes RJ, Altman DG (1995) Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. JAMA 273:408–412

Higgins JPT, Green S (eds) (2005) Identifying and measuring heterogeneity. Cochrane Handbook for Systematic Reviews of Interventions 4.2.5. Wiley, Chichester, UK

Montori VM, Devereaux PJ, Adhikari NK, Burns KE, Eggert CH, Briel M, Lacchetti C, Leung TW, Darling E, Bryant DM, Bucher HC, Schunemann HJ, Meade MO, Cook DJ, Erwin PJ, Sood A, Sood R, Lo B, Thompson CA, Zhou Q, Mills E, Guyatt GH (2005) Randomized trials stopped early for benefit: a systematic review. JAMA 294:2203–2209

Friedrich JO, Adhikari NK, Beyene J (2008) The ratio of means method as an alternative to mean differences for analyzing continuous outcome variables in meta-analysis: a simulation study. BMC Med Res Methodol 8:32

Higgins JP, Thompson SG (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21:1539–1558

Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327:557–560

Begg CB, Mazumdar M (1994) Operating characteristics of a rank correlation test for publication bias. Biometrics 50:1088–1101

Macaskill P, Walter SD, Irwig L (2001) A comparison of methods to detect publication bias in meta-analysis. Stat Med 20:641–654

Chan MC, Hsu JY, Liu HH, Lee YL, Pong SC, Chang LY, Kuo BI, Wu CL (2007) Effects of prone position on inflammatory markers in patients with ARDS due to community-acquired pneumonia. J Formos Med Assoc = Taiwan yi zhi 106:708–716

Curley MA, Hibberd PL, Fineman LD, Wypij D, Shih MC, Thompson JE, Grant MJ, Barr FE, Cvijanovich NZ, Sorce L, Luckett PM, Matthay MA, Arnold JH (2005) Effect of prone positioning on clinical outcomes in children with acute lung injury: a randomized controlled trial. JAMA 294:229–237

Fernandez R, Trenchs X, Klamburg J, Castedo J, Serrano JM, Besso G, Tirapu JP, Santos A, Mas A, Parraga M, Jubert P, Frutos F, Anon JM, Garcia M, Rodriguez F, Yebenes JC, Lopez MJ (2008) Prone positioning in acute respiratory distress syndrome: a multicenter randomized clinical trial. Intensive Care Med 34:1487–1491

Voggenreiter G, Aufmkolk M, Stiletto RJ, Baacke MG, Waydhas C, Ose C, Bock E, Gotzen L, Obertacke U, Nast-Kolb D (2005) Prone positioning improves oxygenation in post-traumatic lung injury–a prospective randomized trial. J Trauma 59:333–341 discussion 341-333

Watanabe I, Fujihara H, Sato K, Honda T, Ohashi S, Endoh H, Yamakura T, Taga K, Shimoji K (2002) Beneficial effect of a prone position for patients with hypoxemia after transthoracic esophagectomy. Crit Care Med 30:1799–1802

Beuret P, Carton MJ, Nourdine K, Kaaki M, Tramoni G, Ducreux JC (2002) Prone position as prevention of lung injury in comatose patients: a prospective, randomized, controlled study. Intensive Care Med 28:564–569

Friedrich JO, Sud S, Sud M, Adhikari NK (2008) Prone position ventilation for community-acquired pneumonia (letter). J Formos Med Assoc = Taiwan yi zhi 107:191 author reply 192

Chan MC, Hsu JY, Liu HH, Lee YL, Pong SC, Chang LY, Kuo BI, Wu CL (2008) Reply to Friedrich et al. (letter). J Formos Med Assoc = Taiwan yi zhi 107:192

Aufmkolk M, Voggenreiter G, Mattern T (2005) Effect of prone position on lung surfactant composition and function in multiple trauma patients with respiratory dysfunction. Eur J Trauma 31:33–38

Curley MA, Arnold JH, Thompson JE, Fackler JC, Grant MJ, Fineman LD, Cvijanovich N, Barr FE, Molitor-Kirsch S, Steinhorn DM, Matthay MA, Hibberd PL (2006) Clinical trial design–effect of prone positioning on clinical outcomes in infants and children with acute respiratory distress syndrome. J Crit Care 21:23–32 discussion 32–27

Fineman LD, LaBrecque MA, Shih MC, Curley MA (2006) Prone positioning can be safely performed in critically ill infants and children. Pediatr Crit Care Med 7:413–422

Gattinoni L, Tognoni G, Brazzi L, Latini R (1997) Ventilation in the prone position. The Prone-Supine Study Collaborative Group. Lancet 350:815

Gattinoni L, Vagginelli F, Carlesso E, Taccone P, Conte V, Chiumello D, Valenza F, Caironi P, Pesenti A (2003) Decrease in PaCO2 with prone position is predictive of improved outcome in acute respiratory distress syndrome. Crit Care Med 31:2727–2733

Lemasson S, Ayzac L, Girard R, Gaillard S, Pavaday K, Guerin C (2006) Does gas exchange response to prone position predict mortality in hypoxemic acute respiratory failure? Intensive Care Med 32:1987–1993

Leal RP, Gonzalez R, Gaona C, Garcia G, Maldanado A, Dominguez-Cherit G (1997) Randomized trial compare prone vs supine position in patients with ARDS (abstract). Am J Respir Crit Care Med 155:A745

Gaillard S, Guerin C, Avzac L, Girard R (2000) A multicenter randomized controlled trial of prone position in acute respiratory failure [abstract]. Am J Respir Crit Care Med 161:A380

Papazian L, Gainnier M, Marin V, Donati S, Arnal JM, Demory D, Roch A, Forel JM, Bongrand P, Bregeon F, Sainty JM (2005) Comparison of prone positioning and high-frequency oscillatory ventilation in patients with acute respiratory distress syndrome. Crit Care Med 33:2162–2171

Demory D, Michelet P, Arnal JM, Donati S, Forel JM, Gainnier M, Bregeon F, Papazian L (2007) High-frequency oscillatory ventilation following prone positioning prevents a further impairment in oxygenation. Crit Care Med 35:106–111

Ibrahim TS, El-Mohamady HS (2007) Inhaled nitric oxide and prone position: How far they can improve oxygenation in pediatric patients with acute respiratory distress syndrome? J Med Sci 7:390–395

Guerin C (2009) Effect of early prone postioning on mortality in patients with severe and persistent acute respiratory distress syndrome. Reanimation 18:146–153

Gattinoni L, Pesenti A (2005) The concept of “baby lung”. Intensive Care Med 31:776–784

Greenland S, Morgenstern H (1989) Ecological bias, confounding, and effect modification. Int J Epidemiol 18:269–274

Derdak S, Mehta S, Stewart TE, Smith T, Rogers M, Buchman TG, Carlin B, Lowson S, Granton J (2002) High-frequency oscillatory ventilation for acute respiratory distress syndrome in adults: a randomized, controlled trial. Am J Respir Crit Care Med 166:801–808

Adhikari NK, Burns KE, Friedrich JO, Granton JT, Cook DJ, Meade MO (2007) Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and meta-analysis. BMJ 334:779

Bein T, Ritzka M, Schmidt F, Taeger K (2007) Positioning therapy in intensive care medicine in Germany. Results of a national survey (German). Der Anaesthesist 56:226–231

Kahn JM, Goss CH, Heagerty PJ, Kramer AA, O’Brien CR, Rubenfeld GD (2006) Hospital volume and the outcomes of mechanical ventilation. N Engl J Med 355:41–50

Assmann SF, Pocock SJ, Enos LE, Kasten LE (2000) Subgroup analysis and other (mis)uses of baseline data in clinical trials. Lancet 355:1064–1069

Oxman AD, Guyatt GH (1992) A consumer’s guide to subgroup analyses. Ann Intern Med 116:78–84

Sud S, Douketis J (2009) ACP Journal Club. The devil is in the details… or not? A primer on individual patient data meta-analysis. Ann Intern Med 151:JC1-2, JC1-3

Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, Lamy M, Legall JR, Morris A, Spragg R (1994) The American–European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 149:818–824

Haynes RB, McKibbon KA, Wilczynski NL, Walter SD, Werre SR (2005) Optimal search strategies for retrieving scientifically strong studies of treatment from Medline: analytical survey. BMJ 330:1179

Wong SS, Wilczynski NL, Haynes RB (2006) Developing optimal search strategies for detecting clinically sound treatment studies in EMBASE. J Med Libr Assoc 94:41–47