Proliferation inhibition of human cervical cancer HeLa cells by Casticin in vitro

Jing Xie1, Jun Bai1, Xin Sheng2, Ji Cao2, Wei Xie1
1Department of Gynecology and Obstetrics, The First Affiliated Hospital of the University of South China, Hengyang, China
2Laboratory of Medicine Engineering, Medical College, Hunan Normal University, Changsha, China

Tóm tắt

Từ khóa


Tài liệu tham khảo

Lin S, Zhang H, Han T, et al. In vivo effect of Casticin on acute inflammation. J Chin Integ Med (Chinese), 2007, 5: 573–576.

Hu Y, Xin HL, Zhang QY, et al. Anti-nociceptive and anti-hyperprolactinemia activities of Fructus Viticis and its effective fractions and chemical constituents. Phytomedicine, 2007, 14: 668–674.

Shen JK, Du HP, Yang M, et al. Casticin induces leukemic cell death through apoptosis and mitotic catastrophe. Ann Hematol, 2009, 88: 743–752.

Hu Y, Hou TT, Zhang QY, et al. Evaluation of the estrogenic activity of the constituents in the fruits of Vitex rotundifolia L. for the potential treatment of premenstrual syndrome. J Pharm Pharmacol, 2007, 59: 1307–1312.

Xiao H, Gong WJ, Cao JP, et al. Influence of CDK1 and CDK2 siRNA interference on tumor cell cycle and cell apoptosis. Chinese-German J Clin Oncol, 2009, 8: 371–374.

Haïdara K, Zamir L, Shi QW, et al. The flavonoid Casticin has multiple mechanisms of tumor cytotoxicity action. Cancer Lett, 2006, 242: 180–190.

Kobayakawa J, Sato-Nishimori F, Moriyasu M, et al. G2-M arrest and antimitotic activity mediated by Casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil.). Cancer Lett, 2004, 208: 59–64.

Li WX, Cui CB, Cai B, et al. Flavonoids from Vitex trifolia L. inhibit cell cycle progression at G2/M phase and induce apoptosis in mammalian cancer cells. J Asian Nat Prod Res, 2005, 7: 615–626.

Suzuki T, Urano T, Miki Y, et al. Nuclear cyclin B1 in human breast carcinoma as a potent prognostic factor. Cancer Sci, 2007, 98: 644–651.

Buchynska LG, Nesina IP, Yurchenko NP, et al. Expression of p53, p21WAF1/CIP1, p16INK4A and Ki-67 proteins in serous ovarian tumors. Exp Oncol, 2007, 29: 49–53.