Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin–Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H–Related Protein-5 (FHR5) Deposition
Tóm tắt
Từ khóa
Tài liệu tham khảo
McGrogan, 2011, The incidence of primary glomerulonephritis worldwide: a systematic review of the literature, Nephrol Dial Transplant, 26, 414, 10.1093/ndt/gfq665
Jennette, 1988, The immunohistology of IgA nephropathy, Am J Kidney Dis, 12, 348, 10.1016/S0272-6386(88)80022-2
Knoppova, 2016, The origin and activities of IgA1-containing immune complexes in IgA nephropathy, Front Immunol, 7, 117, 10.3389/fimmu.2016.00117
D'Amico, 2004, Natural history of idiopathic IgA nephropathy and factors predictive of disease outcome, Semin Nephrol, 24, 179, 10.1016/j.semnephrol.2004.01.001
Rauen, 2015, Intensive supportive care plus immunosuppression in IgA nephropathy, N Engl J Med, 373, 2225, 10.1056/NEJMoa1415463
Maillard, 2015, Current understanding of the role of complement in IgA nephropathy, J Am Soc Nephrol, 26, 1503, 10.1681/ASN.2014101000
Zwirner, 1997, Activated complement C3: a potentially novel predictor of progressive IgA nephropathy, Kidney Int, 51, 1257, 10.1038/ki.1997.171
Kim, 2012, Decreased circulating C3 levels and mesangial C3 deposition predict renal outcome in patients with IgA nephropathy, PLoS One, 7
Medjeral-Thomas, 2017, Circulating complement factor H-related proteins 1 and 5 correlate with disease activity in IgA nephropathy, Kidney Int, 92, 942, 10.1016/j.kint.2017.03.043
Tortajada, 2017, Elevated factor H-related protein 1 and factor H pathogenic variants decrease complement regulation in IgA nephropathy, Kidney Int, 92, 953, 10.1016/j.kint.2017.03.041
Kjaer, 2013, Toward a structure-based comprehension of the lectin pathway of complement, Mol Immunol, 56, 413, 10.1016/j.molimm.2013.05.007
Miyazaki, 1984, Glomerular deposition and serum levels of complement control proteins in patients with IgA nephropathy, Clin Nephrol, 21, 335
Berthoux, 2012, Autoantibodies targeting galactose-deficient IgA1 associate with progression of IgA nephropathy, J Am Soc Nephrol, 23, 1579, 10.1681/ASN.2012010053
Thiel, 2007, Complement activating soluble pattern recognition molecules with collagen-like regions, mannan-binding lectin, ficolins and associated proteins, Mol Immunol, 44, 3875, 10.1016/j.molimm.2007.06.005
Roos, 2001, Human IgA activates the complement system via the mannan-binding lectin pathway, J Immunol, 167, 2861, 10.4049/jimmunol.167.5.2861
Guo, 2017, Mannose-binding lectin levels could predict prognosis in IgA nephropathy, J Am Soc Nephrol, 28, 3175, 10.1681/ASN.2017010076
Roos, 2006, Glomerular activation of the lectin pathway of complement in IgA nephropathy is associated with more severe renal disease, J Am Soc Nephrol, 17, 1724, 10.1681/ASN.2005090923
Espinosa, 2014, Association of C4d deposition with clinical outcomes in IgA nephropathy, Clin J Am Soc Nephrol, 9, 897, 10.2215/CJN.09710913
Roberts, 2009, The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility, Kidney Int, 76, 546, 10.1038/ki.2009.168
Levey, 2009, A new equation to estimate glomerular filtration rate, Ann Intern Med, 150, 604, 10.7326/0003-4819-150-9-200905050-00006
Thiel, 2002, Assays for the functional activity of the mannan-binding lectin pathway of complement activation, Immunobiology, 205, 446, 10.1078/0171-2985-00145
Wittenborn, 2010, Characteristics and biological variations of M-ficolin, a pattern recognition molecule, in plasma, J Innate Immun, 2, 167
Krarup, 2005, Effect of capsulation of opportunistic pathogenic bacteria on binding of the pattern recognition molecules mannan-binding lectin, L-ficolin, and H-ficolin, Infect Immun, 73, 1052, 10.1128/IAI.73.2.1052-1060.2005
Axelgaard, 2013, Investigations on collectin liver 1, J Biol Chem, 288, 23407, 10.1074/jbc.M113.492603
Selman, 2012, An enzyme-linked immunosorbent assay (ELISA) for quantification of human collectin 11 (CL-11, CL-K1), J Immunol Methods, 375, 182, 10.1016/j.jim.2011.10.010
Troldborg, 2015, Collectin liver 1 and collectin kidney 1 and other complement-associated pattern recognition molecules in systemic lupus erythematosus, Clin Exp Immunol, 182, 132, 10.1111/cei.12678
Moller-Kristensen, 2003, Levels of mannan-binding lectin-associated serine protease-2 in healthy individuals, J Immunol Methods, 282, 159, 10.1016/j.jim.2003.08.012
Degn, 2010, Biological variations of MASP-3 and MAp44, two splice products of the MASP1 gene involved in regulation of the complement system, J Immunol Methods, 361, 37, 10.1016/j.jim.2010.07.006
Degn, 2011, MAp19, the alternative splice product of the MASP2 gene, J Immunol Methods, 373, 89, 10.1016/j.jim.2011.08.006
Lomax-Browne, 2017, IgA1 glycosylation is heritable in healthy twins, J Am Soc Nephrol, 28, 64, 10.1681/ASN.2016020184
Benjamini, 2006, Adaptive linear step-up procedures that control the false discovery rate, Biometrika, 93, 491, 10.1093/biomet/93.3.491
Liu, 2005, Human M-ficolin is a secretory protein that activates the lectin complement pathway, J Immunol, 175, 3150, 10.4049/jimmunol.175.5.3150
Troldborg, 2017, Lectin complement pathway proteins in healthy individuals, Clin Exp Immunol, 188, 138, 10.1111/cei.12909
Lu, 1996, Human ficolin: cDNA cloning, demonstration of peripheral blood leucocytes as the major site of synthesis and assignment of the gene to chromosome 9, Biochem J, 313, 473, 10.1042/bj3130473
Thiel, 1992, The concentration of the C-type lectin, mannan-binding protein, in human plasma increases during an acute phase response, Clin Exp Immunol, 90, 31, 10.1111/j.1365-2249.1992.tb05827.x
Endo, 2011, The role of ficolins in the lectin pathway of innate immunity, Int J Biochem Cell Biol, 43, 705, 10.1016/j.biocel.2011.02.003
Thiel, 2012, Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in serum and stoichiometry of lectin pathway components, Clin Exp Immunol, 169, 38, 10.1111/j.1365-2249.2012.04584.x
Degn, 2011, Disease-causing mutations in genes of the complement system, Am J Hum Genet, 88, 689, 10.1016/j.ajhg.2011.05.011
Troldborg, 2015, Levels in plasma of the serine proteases and associated proteins of the lectin pathway are altered in patients with systemic lupus erythematosus, J Rheumatol, 42, 948, 10.3899/jrheum.141163
Tanha, 2017, Plasma ficolin levels and risk of nephritis in Danish patients with systemic lupus erythematosus, Clin Rheumatol, 36, 335, 10.1007/s10067-016-3508-2
Watanabe, 2012, Serum L-ficolin levels in patients with systemic lupus erythematosus, Mod Rheumatol, 22, 899, 10.3109/s10165-012-0616-y
Matsushita, 2013, Ficolins in complement activation, Mol Immunol, 55, 22, 10.1016/j.molimm.2012.08.017
Heja, 2012, Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2, Proc Natl Acad Sci U S A, 109, 10498, 10.1073/pnas.1202588109
Iwaki, 2006, Small mannose-binding lectin-associated protein plays a regulatory role in the lectin complement pathway, J Immunol, 177, 8626, 10.4049/jimmunol.177.12.8626
Zundel, 2004, Characterization of recombinant mannan-binding lectin-associated serine protease (MASP)-3 suggests an activation mechanism different from that of MASP-1 and MASP-2, J Immunol, 172, 4342, 10.4049/jimmunol.172.7.4342
Dobo, 2016, The emerging roles of mannose-binding lectin-associated serine proteases (MASPs) in the lectin pathway of complement and beyond, Immunol Rev, 274, 98, 10.1111/imr.12460
Dahl, 2001, MASP-3 and its association with distinct complexes of the mannan-binding lectin complement activation pathway, Immunity, 15, 127, 10.1016/S1074-7613(01)00161-3
Iwaki, 2011, The role of mannose-binding lectin-associated serine protease-3 in activation of the alternative complement pathway, J Immunol, 187, 3751, 10.4049/jimmunol.1100280
Volanakis, 1996, Complement factor D, a novel serine protease, Protein Sci, 5, 553, 10.1002/pro.5560050401
Murphy, 2002, Factor H-related protein-5: a novel component of human glomerular immune deposits, Am J Kidney Dis, 39, 24, 10.1053/ajkd.2002.29873
Paunas, 2017, Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy, Clin Proteomics, 14, 30, 10.1186/s12014-017-9165-x
Goicoechea de Jorge, 2013, Dimerization of complement factor H-related proteins modulates complement activation in vivo, Proc Natl Acad Sci U S A, 110, 4685, 10.1073/pnas.1219260110
Csincsi, 2015, Factor H-related protein 5 interacts with pentraxin 3 and the extracellular matrix and modulates complement activation, J Immunol, 194, 4963, 10.4049/jimmunol.1403121
Gale, 2010, Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis, Lancet, 376, 794, 10.1016/S0140-6736(10)60670-8
Medjeral-Thomas, 2014, A novel CFHR5 fusion protein causes C3 glomerulopathy in a family without Cypriot ancestry, Kidney Int, 85, 933, 10.1038/ki.2013.348
Gharavi, 2011, Genome-wide association study identifies susceptibility loci for IgA nephropathy, Nat Genet, 43, 321, 10.1038/ng.787
Zhu, 2015, Variants in complement factor H and complement factor H-related protein genes, CFHR3 and CFHR1, affect complement activation in IgA nephropathy, J Am Soc Nephrol, 26, 1195, 10.1681/ASN.2014010096
Herzog, 2017, First treatment of relapsing rapidly progressive IgA nephropathy with eculizumab after living kidney donation: a case report, Transplant Proc, 49, 1574, 10.1016/j.transproceed.2017.02.044
Ring, 2015, Use of eculizumab in crescentic IgA nephropathy: proof of principle and conundrum?, Clin Kidney J, 8, 489, 10.1093/ckj/sfv076
Rosenblad, 2014, Eculizumab treatment for rescue of renal function in IgA nephropathy, Pediatr Nephrol, 29, 2225, 10.1007/s00467-014-2863-y