Progression to Malignancy in the Polyoma Middle T Oncoprotein Mouse Breast Cancer Model Provides a Reliable Model for Human Diseases

Greenlee, 2000, Cancer statistics, 2000, CA Cancer J Clin, 50, 7, 10.3322/canjclin.50.1.7

Lakhani, 1999, The transition from hyperplasia to invasive carcinoma of the breast, J Pathol, 187, 272, 10.1002/(SICI)1096-9896(199902)187:3<272::AID-PATH265>3.0.CO;2-2

Merlino, 1994, Regulatory imbalances in cell proliferation and cell death during oncogenesis in transgenic mice, Semin Cancer Biol, 5, 13

Green, 2000, The C3(1)/SV40 T-antigen transgenic mouse model of mammary cancer: ductal epithelial cell targeting with multistage progression to carcinoma, Oncogene, 19, 1020, 10.1038/sj.onc.1203280

Furth, 1998, SV40 rodent tumour models as paradigms of human disease: transgenic mouse models, Dev Biol Stand, 94, 281

Macleod, 1999, Insights into cancer from transgenic mouse models, J Pathol, 187, 43, 10.1002/(SICI)1096-9896(199901)187:1<43::AID-PATH246>3.0.CO;2-P

Lin, 2001, Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy, J Exp Med, 193, 727, 10.1084/jem.193.6.727

Guy, 1992, Induction of mammary tumors by expression of polyomovirus middle T oncogenes: a transgenic mouse model of a metastatic disease, Mol Cell Biol, 12, 954, 10.1128/MCB.12.3.954

Dankort, 2000, Signal transduction in mammary tumorigenesis: a transgenic perspective, Oncogene, 19, 1038, 10.1038/sj.onc.1203272

Asch, 1996, Tumor viruses and endogenous retrotransposons in mammary tumorigenesis, J Mammary Gland Biol Neoplasia, 1, 49, 10.1007/BF02096302

Dawe, 1987, Variations in polyoma virus genotype in relation to tumor induction in mice. Characterization of wild type strains with widely differing tumor profiles, Am J Pathol, 127, 243

Brison, 1993, Gene amplification and tumor progression, Biochim Biophys Acta, 1155, 25

Lapidus, 1998, The loss of estrogen and progesterone receptor gene expression in human breast cancer, J Mammary Gland Biol Neoplasia, 3, 85, 10.1023/A:1018778403001

Menard, 2000, Role of HER2 gene overexpression in breast carcinoma, J Cell Physiol, 182, 150, 10.1002/(SICI)1097-4652(200002)182:2<150::AID-JCP3>3.0.CO;2-E

Bieche, 1995, Genetic alterations in breast cancer, Genes Chromosom Cancer, 14, 227, 10.1002/gcc.2870140402

Bissell, 2002, The organizing principle: microenvironmental influences in the normal and malignant breast, Differentiation, 70, 537, 10.1046/j.1432-0436.2002.700907.x

Nguyen, 2002, Colony stimulating factor-1 is required to recruit macrophages into the mammary gland to facilitate mammary ductal outgrowth, Dev Biol, 247, 11, 10.1006/dbio.2002.0669

Tong, 1999, Progesterone inhibits estrogen-induced cyclin D1 and cdk4 nuclear translocation, cyclin E, A-cdk2 kinase activation and cell proliferation in uterine epithelial cells in mice, Mol Cell Biol, 19, 2252, 10.1128/MCB.19.3.2251

Gouon-Evans, 2000, Postnatal mammary gland development requires macrophages and eosinophils, Development, 127, 2269, 10.1242/dev.127.11.2269

Sambrook, 1989

Cardiff, 2000, The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting, Oncogene, 19, 968, 10.1038/sj.onc.1203277

Richert, 2000, An atlas of mouse mammary gland development, J Mammary Gland Biol Neoplasia, 5, 227, 10.1023/A:1026499523505

Howard, 2000, Human breast development, J Mammary Gland Biol Neoplasia, 5, 119, 10.1023/A:1026487120779

Mallon, 2000, The basic pathology of human breast cancer, J Mammary Gland Biol Neoplasia, 5, 139, 10.1023/A:1026439204849

Gouon, 2002, Requirement of macrophages and eosinophils and their cytokines/chemokines for mammary gland development, Breast Cancer Res, 4, 155, 10.1186/bcr441

Neville, 2002, Hormonal regulation of mammary differentiation and milk secretion, J Mammary Gland Biol Neoplasia, 7, 49, 10.1023/A:1015770423167

Shyamala, 1999, Progesterone signaling and mammary gland morphogenesis, J Mammary Gland Biol Neoplasia, 4, 89, 10.1023/A:1018760721173

Roskelley, 2002, The dominance of the microenvironment in breast and ovarian cancer, Semin Cancer Biol, 12, 97, 10.1006/scbi.2001.0417

Blackshear, 2001, Genetically engineered rodent models of mammary gland carcinogenesis: an overview, Toxicol Pathol, 29, 105, 10.1080/019262301301418919

Black, 1972, Association of atypical characteristics of benign breast lesions with subsequent risk of breast cancer, Cancer, 29, 338, 10.1002/1097-0142(197202)29:2<338::AID-CNCR2820290212>3.0.CO;2-U

Dupont, 1985, Risk factors for breast cancer in women with proliferative breast disease, N Engl J Med, 312, 146, 10.1056/NEJM198501173120303

Betsill, 1978, Intraductal carcinoma. Long-term follow-up after treatment by biopsy alone, JAMA, 239, 1863, 10.1001/jama.1978.03280450035020

Couch, 1997, BRCA1 mutations in women attending clinics that evaluate the risk of breast cancer, N Engl J Med, 336, 1409, 10.1056/NEJM199705153362002

Xu, 1999, Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation, Nat Genet, 22, 37, 10.1038/8743

Buckley, 1993, Expression and amplification of cyclin genes in human breast cancer, Oncogene, 8, 2127

Matsui, 1990, Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice, Cell, 61, 1147, 10.1016/0092-8674(90)90077-R

Andres, 1987, Ha-ras oncogene expression directed by a milk protein gene promoter: tissue specificity, hormonal regulation, and tumor induction in transgenic mice, Proc Natl Acad Sci USA, 84, 1299, 10.1073/pnas.84.5.1299

Sandgren, 1995, Inhibition of mammary gland involution is associated with transforming growth factor alpha but not c-myc-induced tumorigenesis in transgenic mice, Cancer Res, 55, 3915

Tsukamoto, 1988, Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice, Cell, 55, 619, 10.1016/0092-8674(88)90220-6

Maroulakou, 1994, Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene, Proc Natl Acad Sci USA, 91, 11236, 10.1073/pnas.91.23.11236

Russo, 1998, Role of hormones in mammary cancer initiation and progression, J Mammary Gland Biol Neoplasia, 3, 49, 10.1023/A:1018770218022

Jamerson, 2000, Dual regulation of proliferation and apoptosis: c-myc in bitransgenic murine mammary tumor models, Oncogene, 19, 1065, 10.1038/sj.onc.1203268

Li, 2000, Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer, Oncogene, 19, 1002, 10.1038/sj.onc.1203273

Maglione, 2001, Transgenic polyoma middle-T mice model premalignant mammary disease, Cancer Res, 61, 8298

Sapi, 1999, The role of CSF-1 in normal and neoplastic breast physiology, Proc Soc Exp Biol Med, 220, 1, 10.3181/00379727-220-44337

Leek, 2002, Tumor-associated macrophages in breast cancer, J Mammary Gland Biol Neoplasia, 7, 177, 10.1023/A:1020304003704