Progression of myelodysplasia to acute lymphoblastic leukaemia: Implications for disease biology

Leukemia Research - Tập 30 Số 2 - Trang 233-239 - 2006
Patricia Disperati1,2, Christine V. Ichim3,4, Denis Tkachuk5,6, Kathy Chun5,6, Andre C. Schuh3,1,7, Richard A. Wells3,7,4
1Department of Medical Oncology and Hematology, Princess Margaret Hospital, University Health Network, Toronto, Ont., Canada
2Institute of Medical Sciences, University of Toronto, Toronto, Ont., Canada
3Department of Medical Biophysics, University of Toronto, Toronto, ONT, Canada
4Myelodysplastic Syndrome Program, Toronto Sunnybrook Regional Cancer Centre, Medical Oncology and Haematology, 2075 Bayview Avenue, T-Wing, T2-058 Toronto, Ont., Canada M4N 2M5
5Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ont., Canada
6Toronto Medical Laboratories, Princess Margaret Hospital, University Health Network, Toronto, Ont., Canada
7Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, Ont., Canada

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Bonnet, 1997, Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell, Nat Med, 3, 730, 10.1038/nm0797-730

Singh, 2003, Identification of a cancer stem cell in human brain tumors, Cancer Res, 63, 5821

Singh, 2004, Identification of human brain tumour initiating cells, Nature, 432, 396, 10.1038/nature03128

Al-Hajj, 2003, Prospective identification of tumorigenic breast cancer cells, Proc Natl Acad Sci U S A, 100, 3983, 10.1073/pnas.0530291100

Sole, 2000, Incidence, characterization and prognostic significance of chromosomal abnormalities in 640 patients with primary myelodysplastic syndromes Grupo Cooperativo Espanol de Citogenetica Hematologica, Br J Haematol, 108, 346, 10.1046/j.1365-2141.2000.01868.x

Wetzler, 1999, Prospective karyotype analysis in adult acute lymphoblastic leukemia: the cancer and leukemia Group B experience, Blood, 93, 3983

Germing, 2000, Validation of the WHO proposals for a new classification of primary myelodysplastic syndromes: a retrospective analysis of 1600 patients, Leuk Res, 24, 983, 10.1016/S0145-2126(00)00088-6

Raghavachar, 1987, Analyses of phenotype and genotype in acute lymphoblastic leukemias at first presentation and in relapse, Blood, 70, 1079, 10.1182/blood.V70.4.1079.1079

Shi, 2004, Transformation of myelodysplastic syndromes into acute myeloid leukemias, Chin Med J (Engl), 117, 963

Janssen, 1989, Clonal analysis of myelodysplastic syndromes: evidence of multipotent stem cell origin, Blood, 73, 248, 10.1182/blood.V73.1.248.248

Culligan, 1992, Clonal lymphocytes are detectable in only some cases of MDS, Br J Haematol, 81, 346, 10.1111/j.1365-2141.1992.tb08238.x

van Kamp, 1992, Blood, 80, 1774, 10.1182/blood.V80.7.1774.1774

van Lom, 1995, Cytogenetic clonality analysis in myelodysplastic syndrome: monosomy 7 can be demonstrated in the myeloid and in the lymphoid lineage, Leukemia, 9, 1818

Hamblin, 1992, Immunologic abnormalities in myelodysplastic syndromes, Hematol Oncol Clin North Am, 6, 571, 10.1016/S0889-8588(18)30329-0

Komatsu, 1988, Simultaneous expression of lymphoid and myeloid phenotypes in acute leukemia arising from myelodysplastic syndrome, Am J Hematol, 28, 103, 10.1002/ajh.2830280208

Nilsson, 2002, Involvement and functional impairment of the CD34(+)CD38(−)Thy-1(+) hematopoietic stem cell pool in myelodysplastic syndromes with trisomy 8, Blood, 100, 259, 10.1182/blood-2001-12-0188

Nilsson, 2000, Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: evidence for involvement at the hematopoietic stem cell level, Blood, 96, 2012, 10.1182/blood.V96.6.2012

Haase, 1997, Cytogenetic analysis of CD34+ subpopulations in AML and MDS characterized by the expression of CD38 and CD117, Leukemia, 11, 674, 10.1038/sj.leu.2400638

Billstrom, 1997, Clonal CD5-positive B lymphocytes in myelodysplastic syndrome with systemic vasculitis and trisomy 8, Ann Hematol, 74, 37, 10.1007/s002770050253

Anastasi, 1993, Cytogenetic clonality in myelodysplastic syndromes studied with fluorescence in situ hybridization: lineage, response to growth factor therapy, and clone expansion, Blood, 81, 1580, 10.1182/blood.V81.6.1580.1580

Heaney, 1999, Myelodysplasia, N Engl J Med, 340, 1649, 10.1056/NEJM199905273402107

Greenberg, 1986, In vitro culture techniques defining biological abnormalities in the myelodysplastic syndromes and myeloproliferative disorders, Clin Haematol, 15, 973

Kibbelaar, 1992, Combined immunophenotyping and DNA in situ hybridization to study lineage involvement in patients with myelodysplastic syndromes, Blood, 79, 1823, 10.1182/blood.V79.7.1823.1823

Abrahamson, 1991, Clonality of cell populations in refractory anaemia using combined approach of gene loss and X-linked restriction fragment length polymorphism-methylation analyses, Br J Haematol, 79, 550, 10.1111/j.1365-2141.1991.tb08080.x

Gerritsen, 1992, Clonal analysis of myelodysplastic syndrome: monosomy 7 is expressed in the myeloid lineage, but not in the lymphoid lineage as detected by fluorescent in situ hybridization, Blood, 80, 217, 10.1182/blood.V80.1.217.217

Gilliland, 1991, Clonality in myeloproliferative disorders: analysis by means of the polymerase chain reaction, Proc Natl Acad Sci U S A, 88, 6848, 10.1073/pnas.88.15.6848

Grier, 1986, Cytogenetic evidence for involvement of erythroid progenitors in a child with therapy linked myelodysplasia, Br J Haematol, 64, 513, 10.1111/j.1365-2141.1986.tb02207.x

Kere, 1987, Monosomy 7 in granulocytes and monocytes in myelodysplastic syndrome, N Engl J Med, 316, 499, 10.1056/NEJM198702263160902

Kroef, 1993, Myeloid but not lymphoid cells carry the 5q deletion: polymerase chain reaction analysis of loss of heterozygosity using mini-repeat sequences on highly purified cell fractions, Blood, 81, 1849, 10.1182/blood.V81.7.1849.1849

Le Beau, 1986, Clinical and cytogenetic correlations in 63 patients with therapy-related myelodysplastic syndromes and acute nonlymphocytic leukemia: further evidence for characteristic abnormalities of chromosomes no. 5 and 7, J Clin Oncol, 4, 325, 10.1200/JCO.1986.4.3.325

Kohno, 1996, Progression from myelodysplastic syndrome to acute lymphoblastic leukaemia with Philadelphia chromosome and p190 BCR-ABL transcript, Br J Haematol, 93, 389, 10.1046/j.1365-2141.1996.4931034.x

Ma, 2004, Circulating myeloid and lymphoid precursor dendritic cells are clonally involved in myelodysplastic syndromes, Leukemia, 18, 1451, 10.1038/sj.leu.2403430

Benito, 2003, NOD/SCID mice transplanted with marrow from patients with myelodysplastic syndrome (MDS) show long-term propagation of normal but not clonal human precursors, Leuk Res, 27, 425, 10.1016/S0145-2126(02)00221-7

Thanopoulou, 2004, Engraftment of NOD/SCID-beta2 microglobulin null mice with multilineage neoplastic cells from patients with myelodysplastic syndrome, Blood, 103, 4285, 10.1182/blood-2003-09-3192

Kerbauy, 2004, Engraftment of distinct clonal MDS-derived hematopoietic precursors in NOD/SCID-beta2-microglobulin-deficient mice after intramedullary transplantation of hematopoietic and stromal cells, Blood, 104, 2202, 10.1182/blood-2004-04-1518

Iwase, 1995, Analysis of bone marrow and peripheral blood immunoregulatory lymphocytes in patients with myelodysplastic syndrome, Ann Hematol, 71, 293, 10.1007/BF01697982

Fujii, 2003, Severe and selective deficiency of interferon-gamma-producing invariant natural killer T cells in patients with myelodysplastic syndromes, Br J Haematol, 122, 617, 10.1046/j.1365-2141.2003.04465.x

Tan, 1993, Research on the activity and quantity of natural killer cells and T lymphocytes in myelodysplastic syndrome patients, Zhonghua Nei Ke Za Zhi, 32, 319

Amin, 2003, Increased apoptosis in bone marrow B lymphocytes but not T lymphocytes in myelodysplastic syndrome, Blood, 102, 1866, 10.1182/blood-2003-01-0221

Srivannaboon, 2001, Hypogammaglobulinemia and reduced numbers of B-cells in children with myelodysplastic syndrome, J Pediatr Hematol Oncol, 23, 122, 10.1097/00043426-200102000-00011

Flores-Figueroa, 2005, Mesenchymal stem cells in myelodysplastic syndromes: phenotypic and cytogenetic characterization, Leuk Res, 29, 215, 10.1016/j.leukres.2004.06.011

Tauro, 2001, Assessment of stromal function, and its potential contribution to deregulation of hematopoiesis in the myelodysplastic syndromes, Haematologica, 86, 1038

Span, 2005, Programmed cell death is an intrinsic feature of MDS progenitors, predominantly found in the cluster-forming cells, Exp Hematol, 33, 435, 10.1016/j.exphem.2004.12.009

Li, 1999, The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity, J Exp Med, 189, 1399, 10.1084/jem.189.9.1399

Kuribara, 2004, Roles of Bim in apoptosis of normal and Bcr-Abl-Expressing hematopoietic progenitors, Mol Cell Biol, 24, 6172, 10.1128/MCB.24.14.6172-6183.2004

Sato, 2004, Transformation of myelodysplastic syndrome to acute lymphoblastic leukemia: a case report and review of the literature, Int J Hematol, 79, 147, 10.1532/IJH97.03137

Abruzzese, 1996, Progression of a myelodysplastic syndrome to pre-B acute lymphoblastic leukemia: a case report and cell lineage study, Ann Hematol, 73, 35, 10.1007/s002770050197

Follows, 1999, Eosinophilic myelodysplasia transforming to acute lymphoblastic leukaemia, J Clin Pathol, 52, 388, 10.1136/jcp.52.5.388

Ikeda, 2001, Burkitt's acute lymphoblastic leukaemia transformation after myelodysplastic syndrome, Br J Haematol, 115, 69, 10.1046/j.1365-2141.2001.03098.x

Pajor, 1998, Phenotypic and genotypic analyses of blastic cell population suggest that pure B-lymphoblastic leukemia may arise from myelodysplastic syndrome, Leuk Res, 22, 13, 10.1016/S0145-2126(97)00131-8

Kouides, 1995, Transformation of chronic myelomonocytic leukemia to acute lymphoblastic leukemia: case report and review of the literature of lymphoblastic transformation of myelodysplastic syndrome, Am J Hematol, 49, 157, 10.1002/ajh.2830490211

Lima, 1997, Lymphoblastic transformation of myelodysplastic syndrome, Sao Paulo Med J, 115, 1508, 10.1590/S1516-31801997000400009

Escudier, 1996, Acute lymphoblastic leukemia following preleukemic syndromes in adults, Leukemia, 10, 473

Ascensao, 1986, Lymphoblastic transformation of myelodysplastic syndrome, Am J Hematol, 22, 431, 10.1002/ajh.2830220413

Bonati, 1986, Progression of a myelodysplastic syndrome to pre-B acute lymphoblastic leukaemia with unusual phenotype, Br J Haematol, 64, 487, 10.1111/j.1365-2141.1986.tb02204.x

Inoshita, 1985, Acute lymphoblastic leukemia following myelodysplastic syndrome, Am J Clin Pathol, 84, 233, 10.1093/ajcp/84.2.233

Berneman, 1985, A myelodysplastic syndrome preceding acute lymphoblastic leukaemia, Br J Haematol, 60, 353, 10.1111/j.1365-2141.1985.tb07421.x

Pereira, 1985, T lymphoblastic transformation of refractory anaemia with excess of blasts, Clin Lab Haematol, 7, 89, 10.1111/j.1365-2257.1985.tb00010.x

Hussein, 1982, Acute leukemia in idiopathic sideroblastic anemia: response to combination chemotherapy, Blood, 59, 652, 10.1182/blood.V59.3.652.652

Barton, 1980, Acute lymphoblastic leukemia in idiopathic refractory sideroblastic anemia: evidence for a common lymphoid and myeloid progenitor cell, Am J Hematol, 9, 109, 10.1002/ajh.2830090111