Prognostic value of tumor-infiltrating FOXP3+ regulatory T cells in patients with hepatocellular carcinoma

European Journal of Surgical Oncology (EJSO) - Tập 34 Số 2 - Trang 173-179 - 2008
Atsushi Sasaki1, Fumiaki Tanaka2, Koshi Mimori2, Hiromasa Inoue2, Seiichiro Kai3, Kohei Shibata3, Masayuki Ohta3, Seigo Kitano3, Masaki Mori2
1Department of Surgery, National Hospital Organization Miyazaki Hospital, 19403-4 Kawaminami-machi, Miyazaki 889-1301, Japan.
2Department of Surgical Oncology, Medical Institute of Bioregulation, Kyushu University, 4546 Tsurumihara, Beppu, 874-0838, Japan.
3Department of Surgery I, Oita University Faculty of Medicine, 1-1 Yufu 889-5593, Japan

Tóm tắt

Từ khóa


Tài liệu tham khảo

Sasaki, 2006, Improved long-term survival after liver resection for hepatocellular carcinoma in the modern era: a retrospective study from HCV-endemic areas, World J Surg, 30, 1567, 10.1007/s00268-005-0249-9

Hanazaki, 2000, Survival and recurrence after hepatic resection of 386 consecutive patients with hepatocellular carcinoma, J Am Coll Surg, 191, 381, 10.1016/S1072-7515(00)00700-6

Sakaguchi, 1995, Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases, J Immunol, 155, 1151, 10.4049/jimmunol.155.3.1151

Dercamp, 2005, Distinct and overlapping roles of interleukin-10 and CD25+ regulatory T cells in the inhibition of antitumor CD8 T-cell responses, Cancer Res, 65, 8479, 10.1158/0008-5472.CAN-05-1319

Ghiringhelli, 2005, CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner, J Exp Med, 202, 1075, 10.1084/jem.20051511

Curiel, 2004, Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival, Nat Med, 10, 942, 10.1038/nm1093

Badoual, 2006, Prognostic value of tumor-infiltrating CD4+ T-cell subpopulations in head and neck cancers, Clin Cancer Res, 12, 465, 10.1158/1078-0432.CCR-05-1886

Ormandy, 2005, Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma, Cancer Res, 65, 2457, 10.1158/0008-5472.CAN-04-3232

Unitt, 2005, Compromised lymphocytes infiltrate hepatocellular carcinoma: the role of T-regulatory cells, Hepatology, 41, 722, 10.1002/hep.20644

Yang, 2006, Increase of CD4+CD25+ regulatory T-cells in the liver of patients with hepatocellular carcinoma, J Hepatol, 45, 254, 10.1016/j.jhep.2006.01.036

Kono, 2006, CD4(+)CD25 high regulatory T cells increase with tumor stage in patients with gastric and esophageal cancers, Cancer Immunol Immunother, 55, 1064, 10.1007/s00262-005-0092-8

Bueter, 2006, T-cell response to p53 tumor-associated antigen in patients with colorectal carcinoma, Int J Oncol, 28, 431

Liyanage, 2002, Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma, J Immunol, 169, 2756, 10.4049/jimmunol.169.5.2756

Hiraoka, 2006, Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions, Clin Cancer Res, 12, 5423, 10.1158/1078-0432.CCR-06-0369

Wald, 2006, CD4+ CXCR4 high CD69+ T cells accumulate in lung adenocarcinoma, J Immunol, 177, 6983, 10.4049/jimmunol.177.10.6983

Ishibashi, 2006, Expression of Foxp3 in non-small cell lung cancer patients is significantly higher in tumor tissues than in normal tissues, especially in tumors smaller than 30mm, Oncol Rep, 15, 1315

Miller, 2006, CD4+ CD25 high T cells are enriched in the tumor and peripheral blood of prostate cancer patients, J Immunol, 177, 7398, 10.4049/jimmunol.177.10.7398

Unitt, 2006, Tumour lymphocytic infiltrate and recurrence of hepatocellular carcinoma following liver transplantation, J Hepatol, 45, 246, 10.1016/j.jhep.2005.12.027

Kobayashi, 2007, FOXP3+ regulatory T cells affect the development and progression of hepatocarcinogenesis, Clin Cancer Res, 13, 902, 10.1158/1078-0432.CCR-06-2363

Hori, 2003, Control of regulatory T cell development by the transcription factor Foxp3, Science, 299, 1057, 10.1126/science.1079490

Bennett, 2001, The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3, Nat Genet, 27, 20, 10.1038/83713

2003

Wada, 1998, Clinicopathological study on hepatocellular carcinoma with lymphocytic infiltration, Hepatology, 27, 407, 10.1002/hep.510270214

Diederichsen, 2003, Prognostic value of the CD4+/CD8+ ratio of tumour infiltrating lymphocytes in colorectal cancer and HLA-DR expression on tumour cells, Cancer Immunol Immunother, 52, 423, 10.1007/s00262-003-0388-5

Cho, 2003, CD4+ and CD8+ T cells cooperate to improve prognosis of patients with esophageal squamous cell carcinoma, Cancer Res, 63, 1555

Takahashi, 1998, Immunologic self-tolerance maintained by CD25+ CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state, Int Immunol, 10, 1969, 10.1093/intimm/10.12.1969

Sakon, 2000, Clinical significance of hepatic resection in hepatocellular carcinoma: analysis by disease-free survival curves, Arch Surg, 135, 1456, 10.1001/archsurg.135.12.1456

Michel, 1997, Liver resection or transplantation for hepatocellular carcinoma? Retrospective analysis of 215 patients with cirrhosis, J Hepatol, 26, 1274, 10.1016/S0168-8278(97)80462-X

Okuda, 1992, Hepatocellular carcinoma: recent progress, Hepatology, 15, 948, 10.1002/hep.1840150532

Boettler, 2005, T cell with a CD4+ CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection, J Virol, 79, 7860, 10.1128/JVI.79.12.7860-7867.2005

Stoop, 2005, Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection, Hepatology, 41, 771, 10.1002/hep.20649