Prognostic significance of post-clopidogrel platelet reactivity assessed by a point-of-care assay on thrombotic events after drug-eluting stent implantation

Gurbel, 2003, Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity, Circulation, 107, 2908, 10.1161/01.CIR.0000072771.11429.83

Muller, 2001, Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement, Heart, 85, 92, 10.1136/heart.85.1.92

Angiolillo, 2004, High clopidogrel loading dose during coronary stenting: effects on drug response and interindividual variability, Eur Heart J, 25, 1903, 10.1016/j.ehj.2004.07.036

Price, 2006, Onset and offset of platelet inhibition after high-dose clopidogrel loading and standard daily therapy measured by a point-of-care assay in healthy volunteers, Am J Cardiol, 98, 681, 10.1016/j.amjcard.2006.03.054

Serebruany, 2005, Variability in platelet responsiveness to clopidogrel among 544 individuals, J Am Coll Cardiol, 45, 246, 10.1016/j.jacc.2004.09.067

Grossmann, 2004, Variable extent of clopidogrel responsiveness in patients after coronary stenting, Thromb Haemost, 92, 1201, 10.1160/TH04-01-0049

Aleil, 2005, Flow cytometric analysis of intraplatelet VASP phosphorylation for the detection of clopidogrel resistance in patients with ischemic cardiovascular diseases, J Thromb Haemost, 3, 85, 10.1111/j.1538-7836.2004.01063.x

Matetzky, 2004, Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction, Circulation, 109, 3171, 10.1161/01.CIR.0000130846.46168.03

Hochholzer, 2006, Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement, J Am Coll Cardiol, 48, 1742, 10.1016/j.jacc.2006.06.065

Lev, 2006, Aspirin and clopidogrel drug response in patients undergoing percutaneous coronary intervention: the role of dual drug resistance, J Am Coll Cardiol, 47, 27, 10.1016/j.jacc.2005.08.058

Gurbel, 2005, Clopidogrel loading with eptifibatide to arrest the reactivity of platelets: results of the Clopidogrel Loading With Eptifibatide to Arrest the Reactivity of Platelets (CLEAR PLATELETS) study, Circulation, 111, 1153, 10.1161/01.CIR.0000157138.02645.11

Cuisset, 2006, High post-treatment platelet reactivity identified low-responders to dual antiplatelet therapy at increased risk of recurrent cardiovascular events after stenting for acute coronary syndrome, J Thromb Haemost, 4, 542, 10.1111/j.1538-7836.2005.01751.x

Geisler, 2006, Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation, Eur Heart J, 27, 2420, 10.1093/eurheartj/ehl275

Gurbel, 2005, Platelet reactivity in patients and recurrent events post-stenting: results of the PREPARE POST-STENTING Study, J Am Coll Cardiol, 46, 1820, 10.1016/j.jacc.2005.07.041

Gurbel, 2005, Clopidogrel effect on platelet reactivity in patients with stent thrombosis: results of the CREST Study, J Am Coll Cardiol, 46, 1827, 10.1016/j.jacc.2005.07.056

Barragan, 2003, Resistance to thienopyridines: clinical detection of coronary stent thrombosis by monitoring of vasodilator-stimulated phosphoprotein phosphorylation, Catheter Cardiovasc Interv, 59, 295, 10.1002/ccd.10497

Lev, 2007, Platelet reactivity in patients with subacute stent thrombosis compared with non-stent-related acute myocardial infarction, Am Heart J, 153, e41, 10.1016/j.ahj.2006.10.020

von Beckerath, 2006, Correlation of a new point-of-care test with conventional optical aggregometry for the assessment of clopidogrel responsiveness, Thromb Haemost, 95, 910, 10.1160/TH06-01-0046

van Werkum, 2006, A head-to-head comparison between the VerifyNow P2Y12 assay and light transmittance aggregometry for monitoring the individual platelet response to clopidogrel in patients undergoing elective percutaneous coronary intervention, J Thromb Haemost, 4, 2516, 10.1111/j.1538-7836.2006.02187.x

Malinin, 2007, Monitoring platelet inhibition after clopidogrel with the VerifyNow-P2Y12(R) rapid analyzer: the VERIfy Thrombosis risk ASsessment (VERITAS) study, Thromb Res, 119, 277, 10.1016/j.thromres.2006.01.019

von Beckerath, 2007, A double-blind, randomized study on platelet aggregation in patients treated with a daily dose of 150 or 75 mg of clopidogrel for 30 days, Eur Heart J, 28, 1814, 10.1093/eurheartj/ehl489

Malinin, 2006, Validation of a VerifyNow-P2Y12 cartridge for monitoring platelet inhibition with clopidogrel, Methods Find Exp Clin Pharmacol, 28, 315, 10.1358/mf.2006.28.5.990205

Paniccia, 2007, Different methodologies for evaluating the effect of clopidogrel on platelet function in high-risk coronary artery disease patients, J Thromb Haemost, 5, 1839, 10.1111/j.1538-7836.2007.02656.x

Cannon, 2001, American College of Cardiology key data elements and definitions for measuring the clinical management and outcomes of patients with acute coronary syndromes. A report of the American College of Cardiology Task Force on Clinical Data Standards (Acute Coronary Syndromes Writing Committee), J Am Coll Cardiol, 38, 2114, 10.1016/S0735-1097(01)01702-8

Mauri, 2007, Stent thrombosis in randomized clinical trials of drug-eluting stents, N Engl J Med, 356, 1020, 10.1056/NEJMoa067731

Leon, 1998, A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. Stent Anticoagulation Restenosis Study Investigators, N Engl J Med, 339, 1665, 10.1056/NEJM199812033392303

Schomig, 1996, A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stents, N Engl J Med, 334, 1084, 10.1056/NEJM199604253341702

Bertrand, 1998, Randomized multicenter comparison of conventional anticoagulation versus antiplatelet therapy in unplanned and elective coronary stenting. The full anticoagulation versus aspirin and ticlopidine (FANTASTIC) study, Circulation, 98, 1597, 10.1161/01.CIR.98.16.1597

Hall, 1996, A randomized comparison of combined ticlopidine and aspirin therapy versus aspirin therapy alone after successful intravascular ultrasound-guided stent implantation, Circulation, 93, 215, 10.1161/01.CIR.93.2.215

Goods, 1996, Comparison of aspirin alone versus aspirin plus ticlopidine after coronary artery stenting, Am J Cardiol, 78, 1042, 10.1016/S0002-9149(96)00532-2

Muller, 2003, Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement, Thromb Haemost, 89, 783, 10.1055/s-0037-1613462

Gurbel, 2005, The relation of dosing to clopidogrel responsiveness and the incidence of high post-treatment platelet aggregation in patients undergoing coronary stenting, J Am Coll Cardiol, 45, 1392, 10.1016/j.jacc.2005.01.030

Angiolillo, 2007, Randomized comparison of a high clopidogrel maintenance dose in patients with diabetes mellitus and coronary artery disease: results of the Optimizing Antiplatelet Therapy in Diabetes Mellitus (OPTIMUS) study, Circulation, 115, 708, 10.1161/CIRCULATIONAHA.106.667741

Cuisset, 2006, Benefit of a 600-mg loading dose of clopidogrel on platelet reactivity and clinical outcomes in patients with non-ST-segment elevation acute coronary syndrome undergoing coronary stenting, J Am Coll Cardiol, 48, 1339, 10.1016/j.jacc.2006.06.049

Iakovou, 2005, Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents, JAMA, 293, 2126, 10.1001/jama.293.17.2126

Ong, 2005, Thirty-day incidence and six-month clinical outcome of thrombotic stent occlusion after bare-metal, sirolimus, or paclitaxel stent implantation, J Am Coll Cardiol, 45, 947, 10.1016/j.jacc.2004.09.079

Win, 2007, Clinical outcomes and stent thrombosis following off-label use of drug-eluting stents, JAMA, 297, 2001, 10.1001/jama.297.18.2001

Kuchulakanti, 2006, Correlates and long-term outcomes of angiographically proven stent thrombosis with sirolimus- and paclitaxel-eluting stents, Circulation, 113, 1108, 10.1161/CIRCULATIONAHA.105.600155

Machecourt, 2007, Risk factors for stent thrombosis after implantation of sirolimus-eluting stents in diabetic and nondiabetic patients: the EVASTENT Matched-Cohort Registry, J Am Coll Cardiol, 50, 501, 10.1016/j.jacc.2007.04.051

Buonamici, 2007, Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis, J Am Coll Cardiol, 49, 2312, 10.1016/j.jacc.2007.01.094

Jernberg, 2006, Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease, Eur Heart J, 27, 1166, 10.1093/eurheartj/ehi877

Brandt, 2007, A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation, Am Heart J, 153, e9, 10.1016/j.ahj.2006.10.010

Husted, 2006, Pharmacodynamics, pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: a double-blind comparison to clopidogrel with aspirin, Eur Heart J, 27, 1038, 10.1093/eurheartj/ehi754

Mascelli, 2000, Therapeutic heparin concentrations augment platelet reactivity: implications for the pharmacologic assessment of the glycoprotein IIb/IIIa antagonist abciximab, Am Heart J, 139, 696, 10.1016/S0002-8703(00)90050-4

Spertus, 2006, Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: results from the PREMIER registry, Circulation, 113, 2803, 10.1161/CIRCULATIONAHA.106.618066