Prognostic role of diabetes mellitus in hepatocellular carcinoma patients after curative treatments: a meta-analysis

Parkin, 2005, Global cancer statistics, 2002, CA Cancer J Clin, 55, 74, 10.3322/canjclin.55.2.74 Llovet, 2003, Hepatocellular carcinoma: present status and future prospects, J Hepatol, 38, S136, 10.1016/S0168-8278(02)00432-4 Tang, 2004, A decade's studies on metastasis of hepatocellular carcinoma, J Cancer Res Clin Oncol, 130, 187, 10.1007/s00432-003-0511-1 Strickler, 2001, The relation of type 2 diabetes and cancer, Diabetes Technol Ther, 3, 263, 10.1089/152091501300209633 Lai, 2006, Type 2 diabetes and hepatocellular carcinoma: A cohort study in high prevalence area of hepatitis virus infection, Hepatology, 43, 1295, 10.1002/hep.21208 Lagiou, 2000, Role of diabetes mellitus in the etiology of hepatocellular carcinoma, J Natl Cancer Inst, 92, 1096, 10.1093/jnci/92.13.1096 El-Serag, 2004, Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma, Gastroenterology, 126, 460, 10.1053/j.gastro.2003.10.065 Gao, 2009, Diabetes mellitus: a “true” independent risk factor for hepatocellular carcinoma?, Hepatobiliary Pancreat Dis Int, 8, 465 Huo, 2010, Diabetes mellitus as an independent prognostic predictor and its association with renal dysfunction in patients with hepatocellular carcinoma, Liver Int, 30, 198, 10.1111/j.1478-3231.2009.02143.x Amarapurkar, 2008, Impact of diabetes mellitus on outcome of HCC, Ann Hepatol, 7, 148, 10.1016/S1665-2681(19)31871-X Komura, 2007, Impact of diabetes on recurrence of hepatocellular carcinoma after surgical treatment in patients with viral hepatitis, Am J Gastroenterol, 102, 1939, 10.1111/j.1572-0241.2007.01354.x Kawamura, 2008, Diabetes mellitus worsens the recurrence rate after potentially curative therapy in patients with hepatocellular carcinoma associated with nonviral hepatitis, J Gastroenterol Hepatol, 23, 1739, 10.1111/j.1440-1746.2008.05436.x Huo, 2004, Differential mechanism and prognostic impact of diabetes mellitus on patients with hepatocellular carcinoma undergoing surgical and nonsurgical treatment, Am J Gastroenterol, 99, 1479, 10.1111/j.1572-0241.2004.30024.x Poon, 2002, Does diabetes mellitus influence the perioperative outcome or long term prognosis after resection of hepatocellular carcinoma?, Am J Gastroenterol, 97, 1480, 10.1111/j.1572-0241.2002.05792.x No authors listed, 1985, Diabetes mellitus. Report of a WHO Study Group, World Health Organ Tech Rep Ser, 727, 1 Expert Committee on the Diagnosis and Classification of Diabetes Mellitus, 2003, Report of the expert committee on the diagnosis and Classification of diabetes mellitus, Diabetes Care, 26, S5, 10.2337/diacare.26.2007.S5 Schoenleber, 2009, Prognostic role of vascular endothelial growth factor in hepatocellular carcinoma: systematic review and meta-analysis, Br J Cancer, 100, 1385, 10.1038/sj.bjc.6605017 Parmar, 1998, Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints, Stat Med, 17, 2815, 10.1002/(SICI)1097-0258(19981230)17:24<2815::AID-SIM110>3.0.CO;2-8 Nagasue, 1999, Prognostic factors after hepatic resection for hepatocellular carcinoma associated with Child-Turcotte class B and C cirrhosis, Ann Surg, 229, 84, 10.1097/00000658-199901000-00011 Egger, 1998, Bias in location and selection of studies, BMJ, 316, 61, 10.1136/bmj.316.7124.61 Popat, 2004, Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysis, J Clin Oncol, 22, 529, 10.1200/JCO.2004.05.064 Higgins, 2003, Measuring inconsistency in meta-analyses, BMJ, 327, 557, 10.1136/bmj.327.7414.557 Egger, 1997, Bias in meta-analysis detected by a simple, graphical test, BMJ, 315, 629, 10.1136/bmj.315.7109.629 Tierney, 2003, Practical methods for incorporating summary time-to-event data into meta-analysis, Trials, 8, 16, 10.1186/1745-6215-8-16 John, 2002, Outcome of patients with new-onset diabetes mellitus after liver transplantation compared with those without diabetes mellitus, Liver Transpl, 8, 708, 10.1053/jlts.2002.34638 Moon, 2006, Negative impact of new-onset diabetes mellitus on patient and graft survival after liver transplantation: Long-term follow up, Transplantation, 82, 1625, 10.1097/01.tp.0000250361.60415.96 Xu, 2008, Post-transplant diabetes mellitus in liver transplantation: Hangzhou experience, Hepatobiliary Pancreat Dis Int, 7, 465 Huo, 2003, Diabetes mellitus is a risk factor for hepatic decompensation in patients with hepatocellular carcinoma undergoing resection: a longitudinal study, Am J Gastroenterol, 98, 2293, 10.1111/j.1572-0241.2003.07688.x Shirabe, 1999, Postoperative liver failure after major hepatic resection for hepatocellular carcinoma in the modern era with special reference to remnant liver volume, J Am Coll Surg, 188, 304, 10.1016/S1072-7515(98)00301-9 Huo, 2004, Acute renal failure after transarterial chemoembolization for hepatocellular carcinoma: a retrospective study of the incidence, risk factors, clinical course and long-term outcome, Aliment Pharmacol Ther, 19, 999, 10.1111/j.1365-2036.2004.01936.x Shimada, 1994, Estimation of risk of major complications after hepatic resection, Am J Surg, 167, 399, 10.1016/0002-9610(94)90124-4 Wang, 2011, Preoperative serum retinol-binding protein 4 is associated with the prognosis of patients with hepatocellular carcinoma after curative resection, J Cancer Res Clin Oncol, 137, 651, 10.1007/s00432-010-0927-3 Sumie, 2007, Significance of glucose intolerance and SHIP2 expression in hepatocellular carcinoma patients with HCV infection, Oncol Rep, 18, 545 Imai, 2010, Insulin resistance raises the risk for recurrence of stage I hepatocellular carcinoma after curative radiofrequency ablation in hepatitis C virus-positive patients: A prospective, case series study, Hepatol Res, 40, 376, 10.1111/j.1872-034X.2009.00616.x Yanaga, 1993, Effect of diabetes mellitus on hepatic resection, Arch Surg, 128, 445, 10.1001/archsurg.1993.01420160087014 Shimada, 1998, Risk factors linked to postoperative morbidity in patients with hepatocellular carcinoma, Br J Surg, 85, 195, 10.1046/j.1365-2168.1998.00567.x Khan, 2006, Relationship between hepatocellular carcinoma and impaired glucose tolerance among Japanese, Hepatogastroenterology, 53, 742 Martin, 2009, Association of diabetes with survival among cohorts of Indigenous and non-Indigenous Australians with cancer, Cancer Causes Control, 20, 355, 10.1007/s10552-008-9249-z Takamatsu, 2008, Influence of risk factors for metabolic syndrome and non-alcoholic fatty liver disease on the progression and prognosis of hepatocellular carcinoma, Hepatogastroenterology, 55, 609 Miuma, 2009, The level of fasting serum insulin, but not adiponectin, is associated with the prognosis of early stage hepatocellular carcinoma, Oncol Rep, 22, 1415, 10.3892/or_00000583 Coughlin, 2004, Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults, Am J Epidemiol, 159, 1160, 10.1093/aje/kwh161 Matsumata, 1995, Morbidity and mortality after hepatic resection in the modern era, Hepatogastroenterology, 42, 456 Shimada, 1999, Risk factors of the recurrence of hepatocellular carcinoma originating from residual cancer cells after hepatectomy, Hepatogastroenterology, 46, 2469 Huo, 2003, Diabetes mellitus is a recurrence-independent risk factor in patients with hepatitis B virus-related hepatocellular carcinoma undergoing resection, Eur J Gastroenterol Hepatol, 15, 1203, 10.1097/00042737-200311000-00009 Ikeda, 1998, Prognosis of hepatocellular carcinoma with diabetes mellitus after hepatic resection, Hepatology, 27, 1567, 10.1002/hep.510270615 Toyoda, 2001, Impact of diabetes mellitus on the prognosis of patients with hepatocellular carcinoma, Cancer, 91, 957, 10.1002/1097-0142(20010301)91:5<957::AID-CNCR1085>3.0.CO;2-J Wild, 2004, Global prevalence of diabetes: estimates for the year 2000 and projections for 2030, Diabetes Care, 27, 1047, 10.2337/diacare.27.5.1047 Saito, 2002, Augmentation effect of postprandial hyperinsulinaemia on growth of human hepatocellular carcinoma, Gut, 51, 100, 10.1136/gut.51.1.100 Dellon, 2005, Diabetes and hepatocellular carcinoma: associations, biologic plausibility, and clinical implications, Gastroenterology, 129, 1132, 10.1053/j.gastro.2005.06.079 Akturk, 2007, Association of serum levels of IGF-I and IGFBP-1 with renal function in patients with type 2 diabetes mellitus, Growth Horm IGF Res, 17, 186, 10.1016/j.ghir.2007.01.007 Lee, 2006, Loss of Raf kinase inhibitor protein promotes cell proliferation and migration of human hepatoma cells, Gastroenterology, 131, 1208, 10.1053/j.gastro.2006.07.012 Alexia, 2004, An evaluation of the role of insulin-like growth factors (IGF) and of type-I IGF receptor signalling in hepatocarcinogenesis and in the resistance of hepatocarcinoma cells against drug-induced apoptosis, Biochem Pharmacol, 68, 1003, 10.1016/j.bcp.2004.05.029 Radcliff, 2005, Insulin-like growth factor-I regulates proliferation and osteoblastic differentiation of calcifying vascular cells via extracellular signal-regulated protein kinase and phosphatidylinositol 3-kinase pathways, Circ Res, 96, 398, 10.1161/01.RES.0000157671.47477.71 Rosen, 2001, The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a Congress Series sponsored by UNESCO-MCBN, the American Diabetes Association and the German Diabetes Society, Diabetes Metab Res Rev, 17, 189, 10.1002/dmrr.196 Tesfamariam, 1992, Free radicals mediate endothelial cell dysfunction caused by elevated glucose, Am J Physiol, 263, H321 Imazeki, 2008, Prevalence of diabetes mellitus and insulin resistance in patients with chronic hepatitis C: comparison with hepatitis B virus-infected and hepatitis C virus-cleared patients, Liver Int, 28, 355, 10.1111/j.1478-3231.2007.01630.x Lauer, 2001, Hepatitis C virus infection, N Engl J Med, 345, 41, 10.1056/NEJM200107053450107 Fong, 2000, Metabolic and nutritional considerations in nonalcoholic fatty liver, Hepatology, 32, 3, 10.1053/jhep.2000.8978 Kawaguchi, 2004, Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3, Am J Pathol, 165, 1499, 10.1016/S0002-9440(10)63408-6 Brechot, 1980, Presence of integrated hepatitis B virus DNA sequences in cellular DNA of human hepatocellular carcinoma, Nature, 286, 533, 10.1038/286533a0 Wang, 2008, Association of chronic hepatitis B virus infection with insulin resistance and hepatic steatosis, J Gastroenterol Hepatol, 23, 779, 10.1111/j.1440-1746.2007.05216.x Donadon, 2008, Association between hepatocellular carcinoma and type 2 diabetes mellitus in Italy: potential role of insulin, World J Gastroenterol, 14, 5695, 10.3748/wjg.14.5695 Bowker, 2006, Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin, Diabetes Care, 29, 254, 10.2337/diacare.29.02.06.dc05-1558 Evans, 2005, Metformin and reduced risk of cancer in diabetic patients, BMJ, 330, 1304, 10.1136/bmj.38415.708634.F7