Prognostic model in patients with metastatic urothelial carcinoma receiving immune checkpoint inhibitors after platinum failure

Current Problems in Cancer - Tập 46 - Trang 100848 - 2022
Joo-Hwan Park1, Inkeun Park1,2, In-Ho Kim3, Joon Young Hur4,5, Inhwan Hwang6,2, Chan Kim7, Hyo-Jeong Kim8, Chi Hoon Maeng9, Kwonoh Park10, Min-Young Lee11, Hyo Jin Lee12, Joo Young Jung13, Bhumsuk Keam14, Se Hoon Park5, Jae Lyun Lee2
1Division of Medical Oncology, Department of Internal Medicine, Gachon University School of Medicine, Gil Medical Center, Incheon, Korea
2Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, KOREA
3Department of Internal Medicine, Division of Medical Oncology, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea
4Division of Hematology and Oncology, Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Seoul, Korea
5Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
6Department of Hematology/Oncology, Yuseong Sun Hospital, Daejeon, Korea
7Medical Oncology, CHA Bundang Medical Center, CHA University, Seongnam, Korea
8Department of Internal Medicine, Division of Hematology-Oncology, School of Medicine, Medical Research Institute, Pusan National University Hospital, Busan, Korea
9Division of Medical Oncology‐Hematology, Department of Medicine, College of Medicine, Kyung Hee University Hospital, Seoul, Korea
10Medical Oncology and Hematology, Department of Internal Medicine, Pusan National University Yangsan Hospital, Gyeongsangnam-do, Korea
11Department of Internal Medicine, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Korea
12Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, KOREA
13Department of Internal Medicine, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea
14Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea

Tài liệu tham khảo

Sung, 2021, Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries, CA Cancer J Clin, 10.3322/caac.21660 Samaratunga, 2012, Recently described and unusual variants of urothelial carcinoma of the urinary bladder, Pathology, 44, 407, 10.1097/PAT.0b013e3283560172 von der Maase, 2005, Long-term survival results of a randomized trial comparing gemcitabine plus cisplatin, with methotrexate, vinblastine, doxorubicin, plus cisplatin in patients with bladder cancer, J Clin Oncol, 23, 4602, 10.1200/JCO.2005.07.757 Park, 2020, Systemic treatment for advanced urothelial cancer: an update on recent clinical trials and current treatment options, Korean J Intern Med, 35, 834, 10.3904/kjim.2020.204 Bellmunt, 2013, Long-term survival results of a randomized phase III trial of vinflunine plus best supportive care versus best supportive care alone in advanced urothelial carcinoma patients after failure of platinum-based chemotherapy, Ann Oncol, 24, 1466, 10.1093/annonc/mdt007 Bellmunt, 2017, Pembrolizumab as second-line therapy for advanced urothelial carcinoma, N Engl J Med, 376, 1015, 10.1056/NEJMoa1613683 Balar, 2017, First-line pembrolizumab in cisplatin-ineligible patients with locally advanced and unresectable or metastatic urothelial cancer (KEYNOTE-052): a multicentre, single-arm, phase 2 study, Lancet Oncol, 18, 1483, 10.1016/S1470-2045(17)30616-2 Balar, 2017, Atezolizumab as first-line treatment in cisplatin-ineligible patients with locally advanced and metastatic urothelial carcinoma: a single-arm, multicentre, phase 2 trial, Lancet, 389, 67, 10.1016/S0140-6736(16)32455-2 Powles, 2020, Avelumab maintenance therapy for advanced or metastatic urothelial carcinoma, N Engl J Med, 383, 1218, 10.1056/NEJMoa2002788 Bajorin, 1999, Long-term survival in metastatic transitional-cell carcinoma and prognostic factors predicting outcome of therapy, J Clin Oncol, 17, 3173, 10.1200/JCO.1999.17.10.3173 Bellmunt, 2010, Prognostic factors in patients with advanced transitional cell carcinoma of the urothelial tract experiencing treatment failure with platinum-containing regimens, J Clin Oncol, 28, 1850, 10.1200/JCO.2009.25.4599 Motzer, 2018, Nivolumab plus ipilimumab versus sunitinib in advanced renal-cell carcinoma, N Engl J Med, 378, 1277, 10.1056/NEJMoa1712126 Eisenhauer, 2009, New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1), Eur J Cancer, 45, 228, 10.1016/j.ejca.2008.10.026 Kang, 2015, Comparing two correlated C indices with right-censored survival outcome: a one-shot nonparametric approach, Stat Med, 34, 685, 10.1002/sim.6370 Chen, 1985, The bootstrap and identification of prognostic factors via Cox's proportional hazards regression model, Stat Med, 4, 39, 10.1002/sim.4780040107 Sauerbrei, 1992, A bootstrap resampling procedure for model building: application to the Cox regression model, Stat Med, 11, 2093, 10.1002/sim.4780111607 Apolo, 2013, Prognostic model for predicting survival of patients with metastatic urothelial cancer treated with cisplatin-based chemotherapy, J Natl Cancer Inst, 105, 499, 10.1093/jnci/djt015 Galsky, 2013, Nomogram for predicting survival in patients with unresectable and/or metastatic urothelial cancer who are treated with cisplatin-based chemotherapy, Cancer, 119, 3012, 10.1002/cncr.28146 Sonpavde, 2018, Nomogram to assess the survival benefit of new salvage agents for metastatic urothelial carcinoma in the era of immunotherapy, Clin Genitourin Cancer, 16, e961, 10.1016/j.clgc.2018.03.016 Taguchi, 2015, Pretreatment neutrophil-to-lymphocyte ratio as an independent predictor of survival in patients with metastatic urothelial carcinoma: a multi-institutional study, Int J Urol, 22, 638, 10.1111/iju.12766 Pond, 2014, A nomogram including baseline prognostic factors to estimate the activity of second-line therapy for advanced urothelial carcinoma, BJU Int, 113, E137, 10.1111/bju.12564 Scott, 2020, Performance status in cancer: not broken, but time for an upgrade?, J Clin Oncol, 38, 2824, 10.1200/JCO.20.00721 Bersanelli, 2018, Patient performance status and cancer immunotherapy efficacy: a meta-analysis, Med Oncol, 35, 132, 10.1007/s12032-018-1194-4 Sonpavde, 2020, Five-factor prognostic model for survival of post-platinum patients with metastatic urothelial carcinoma receiving PD-L1 inhibitors, J Urol, 204, 1173, 10.1097/JU.0000000000001199 Nassar, 2020, A model combining clinical and genomic factors to predict response to PD-1/PD-L1 blockade in advanced urothelial carcinoma, Br J Cancer, 122, 555, 10.1038/s41416-019-0686-0 Ferrucci, 2016, Baseline neutrophils and derived neutrophil-to-lymphocyte ratio: prognostic relevance in metastatic melanoma patients receiving ipilimumab, Ann Oncol, 27, 732, 10.1093/annonc/mdw016 Bilen, 2018, Association between pretreatment neutrophil-to-lymphocyte ratio and outcome of patients with metastatic renal-cell carcinoma treated with nivolumab, Clin Genitourin Cancer, 16, e563, 10.1016/j.clgc.2017.12.015 Jiang, 2018, Pretreatment neutrophil-to-lymphocyte ratio is associated with outcome of advanced-stage cancer patients treated with immunotherapy: a meta-analysis, Cancer Immunol Immunother, 67, 713, 10.1007/s00262-018-2126-z Guthrie, 2013, The systemic inflammation-based neutrophil-lymphocyte ratio: experience in patients with cancer, Crit Rev Oncol Hematol, 88, 218, 10.1016/j.critrevonc.2013.03.010 Valero, 2021, Pretreatment neutrophil-to-lymphocyte ratio and mutational burden as biomarkers of tumor response to immune checkpoint inhibitors, Nat Commun, 12, 729, 10.1038/s41467-021-20935-9 Gonzalez, 2018, Roles of the immune system in cancer: from tumor initiation to metastatic progression, Genes Dev, 32, 1267, 10.1101/gad.314617.118 Balkwill, 2001, Inflammation and cancer: back to Virchow?, Lancet, 357, 539, 10.1016/S0140-6736(00)04046-0 Havel, 2019, The evolving landscape of biomarkers for checkpoint inhibitor immunotherapy, Nat Rev Cancer, 19, 133, 10.1038/s41568-019-0116-x Ren, 2019, Neutrophil-lymphocyte ratio (NLR) predicted prognosis for advanced non-small-cell lung cancer (NSCLC) patients who received immune checkpoint blockade (ICB), Onco Targets Ther, 12, 4235, 10.2147/OTT.S199176 Khaki, 2021, A new prognostic model in patients with advanced urothelial carcinoma treated with first-line immune checkpoint inhibitors, Eur Urol Oncol, 10.1016/j.euo.2020.12.006