Prognostic Significance of miR-215 in Colon Cancer

Hamilton, 2000, Tumors of the colon and rectum, 314

McLornan, 2010, Prognostic significance of TRAIL signaling molecules in stage II and III colorectal cancer, Clin Cancer Res, 16, 3442, 10.1158/1078-0432.CCR-10-0052

O'Connell, 2004, Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging, J Natl Cancer Inst, 96, 1420, 10.1093/jnci/djh275

Longley, 2006, Drug resistance, predictive markers and pharmacogenomics in colorectal cancer, Biochim Biophys Acta, 1766, 184

Chu, 1999, Thymidylate synthase protein and p53 mRNA form an in vivo ribonucleoprotein complex, Mol Cell Biol, 19, 1582, 10.1128/MCB.19.2.1582

Ju, 1999, Regulation of p53 expression by thymidylate synthase, Proc Natl Acad Sci U S A, 96, 3769, 10.1073/pnas.96.7.3769

Sheikh, 1999, Regulation of translation initiation following stress, Oncogene, 18, 6121, 10.1038/sj.onc.1203131

Ju, 2003, Simultaneous gene expression analysis of steady-state and actively translated mRNA populations from osteosarcoma MG-63 cells in response to IL-1α via an open expression analysis platform, Nucleic Acids Res, 31, 5157, 10.1093/nar/gkg702

Fu, 1996, Translational regulation of human p53 gene expression, EMBO J, 15, 4392, 10.1002/j.1460-2075.1996.tb00812.x

Chu, 1991, Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase, Proc Natl Acad Sci U S A, 88, 8977, 10.1073/pnas.88.20.8977

Lee, 1993, The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14, Cell, 75, 843, 10.1016/0092-8674(93)90529-Y

Brennecke, 2003, bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila, Cell, 113, 25, 10.1016/S0092-8674(03)00231-9

Chan, 2005, MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells, Cancer Res, 65, 6029, 10.1158/0008-5472.CAN-05-0137

Ghodgaonkar, 2009, Abrogation of DNA vector-based RNAi during apoptosis in mammalian cells due to caspase-mediated cleavage and inactivation of Dicer-1, Cell Death Differ, 16, 858, 10.1038/cdd.2009.15

Hwang, 2006, MicroRNAs in cell proliferation, cell death, and tumorigenesis, Br J Cancer, 94, 776, 10.1038/sj.bjc.6603023

Tang, 2010, Small RNAs in mammalian germline: tiny for immortal, Differentiation, 79, 141, 10.1016/j.diff.2009.11.002

Navarro, 2010, Small RNAs guide hematopoietic cell differentiation and function, J Immunol, 184, 5939, 10.4049/jimmunol.0902567

Wightman, 1993, Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans, Cell, 75, 855, 10.1016/0092-8674(93)90530-4

He, 2005, A microRNA polycistron as a potential human oncogene, Nature, 435, 828, 10.1038/nature03552

Johnson, 2007, The let-7 microRNA represses cell proliferation pathways in human cells, Cancer Res, 67, 7713, 10.1158/0008-5472.CAN-07-1083

Lu, 2005, MicroRNA expression profiles classify human cancers, Nature, 435, 834, 10.1038/nature03702

Volinia, 2006, A microRNA expression signature of human solid tumors defines cancer gene targets, Proc Natl Acad Sci U S A, 103, 2257, 10.1073/pnas.0510565103

Braun, 2008, p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest, Cancer Res, 68, 10094, 10.1158/0008-5472.CAN-08-1569

Xi, 2006, Differentially regulated micro-RNAs and actively translated messenger RNA transcripts by tumor suppressor p53 in colon cancer, Clin Cancer Res, 12, 2014, 10.1158/1078-0432.CCR-05-1853

He, 2007, A microRNA component of the p53 tumour suppressor network, Nature, 447, 1130, 10.1038/nature05939

He, 2007, The guardian's little helper: microRNAs in the p53 tumor suppressor network, Cancer Res, 67, 11099, 10.1158/0008-5472.CAN-07-2672

Chang, 2007, Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis, Mol Cell, 26, 745, 10.1016/j.molcel.2007.05.010

Corney, 2007, MicroRNA-34b and microRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth, Cancer Res, 67, 8433, 10.1158/0008-5472.CAN-07-1585

Tarasov, 2007, Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest, Cell Cycle, 6, 1586, 10.4161/cc.6.13.4436

Song, 2010, Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells, Mol Cancer, 9, 96, 10.1186/1476-4598-9-96

Fujita, 2008, Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells, Biochem Biophys Res Commun, 377, 114, 10.1016/j.bbrc.2008.09.086

Yang, 2008, MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN, Cancer Res, 68, 425, 10.1158/0008-5472.CAN-07-2488

Song, 2009, Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells, Oncogene, 28, 4065, 10.1038/onc.2009.274

Song, 2008, miR-192 regulates dihydrofolate reductase and cellular proliferation through the p53-microRNA circuit, Clin Cancer Res, 14, 8080, 10.1158/1078-0432.CCR-08-1422

Showalter, 2008, Evaluating the drug-target relationship between thymidylate synthase expression and tumor response to 5-fluorouracil, Cancer Biol Ther, 7, 986, 10.4161/cbt.7.7.6181

Pan, 2006, Role of L2DTL, cell cycle-regulated nuclear and centrosome protein, in aggressive hepatocellular carcinoma, Cell Cycle, 5, 2676, 10.4161/cc.5.22.3500

Higa, 2006, L2DTL/CDT2 interacts with the CUL4/DDB1 complex and PCNA and regulates CDT1 proteolysis in response to DNA damage, Cell Cycle, 5, 1675, 10.4161/cc.5.15.3149

Sansam, 2006, DTL/CDT2 is essential for both CDT1 regulation and the early G2/M checkpoint, Genes Dev, 20, 3117, 10.1101/gad.1482106

Banks, 2006, L2DTL/CDT2 and PCNA interact with p53 and regulate p53 polyubiquitination and protein stability through MDM2 and CUL4A/DDB1 complexes, Cell Cycle, 5, 1719, 10.4161/cc.5.15.3150

Nishitani, 2008, CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation, J Biol Chem, 283, 29045, 10.1074/jbc.M806045200

Shibutani, 2008, Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phase, Dev Cell, 15, 890, 10.1016/j.devcel.2008.10.003

Xi, 2006, Prognostic values of microRNAs in colorectal cancer, Biomark Insights, 2, 113

Xi, 2007, Systematic analysis of microRNA expression of RNA extracted from fresh frozen and formalin-fixed paraffin-embedded samples, RNA, 13, 1668, 10.1261/rna.642907

Singh, 2008, ZEB1 expression in type I vs type II endometrial cancers: a marker of aggressive disease, Mod Pathol, 21, 912, 10.1038/modpathol.2008.82

Brody, 2009, Limits to thymidylate synthase and TP53 genes as predictive determinants for fluoropyrimidine sensitivity and further evidence for RNA-based toxicity as a major influence, Cancer Res, 69, 984, 10.1158/0008-5472.CAN-08-3610