Progesterone suppresses Th17 cell responses, and enhances the development of regulatory T cells, through thymic stromal lymphopoietin-dependent mechanisms in experimental gonococcal genital tract infection

2001 Wu, 2011, The relationship between the symptoms of female gonococcal infections and serum progesterone level and the genotypes of Neisseria gonorrhoeae multi-antigen sequence type (NG-MAST) in Wuhan, China, Eur. J. Clin. Microbiol. Infect. Dis., 30, 113, 10.1007/s10096-010-1040-x Kaushic, 2000, Effect of estradiol and progesterone on susceptibility and immune responses to Chlamydia trachomatis infection in the female reproductive tract, Infect. Immun., 68, 4207, 10.1128/IAI.68.7.4207-4216.2000 Kaushic, 2003, Progesterone increases susceptibility and decreases immune responses to genital Herpes infection, J. Virol., 77, 4558, 10.1128/JVI.77.8.4558-4565.2003 Kalo-Klein, 1989, Candida albicans: cellular immune system interactions during different stages of the menstrual cycle, Am. J. Obstet. Gynecol., 161, 1132, 10.1016/0002-9378(89)90649-2 Nowicki, 2000, Susceptibility to gonococcal infection during the menstrual cycle, J. Am. Med. Assoc., 283, 1291, 10.1001/jama.283.10.1291 Wang, 1999, Risk of HIV infection in oral contraceptive pill users: a meta-analysis, J. Acquir. Immune Defic. Syndr., 21, 51, 10.1097/00126334-199905010-00007 Baeten, 2005, Effect of contraceptive methods on natural history of HIV: studies from the Mombasa cohort, J. Acquir. Immune Defic. Syndr., 38, S18, 10.1097/01.qai.0000167030.18278.0e Miyaura, 2002, Direct and indirect inhibition of Th1 development by progesterone and glucocorticoids, J. Immunol., 168, 1087, 10.4049/jimmunol.168.3.1087 Butts, 2007, Progesterone inhibits mature rat dendritic cells in a receptor-mediated fashion, Int. Immunol., 19, 287, 10.1093/intimm/dxl145 Butts, 2008, Inhibitory effects of progesterone differ in dendritic cells from female and male rodents, Gend. Med., 5, 434, 10.1016/j.genm.2008.11.001 Friend, 1994, A thymic stromal cell line supports in vitro development of surface IgM+ B cells and produces a novel growth factor affecting B and T lineage cells, Exp. Hematol., 22, 321 Sims, 2000, Molecular cloning and biological characterization of a novel murine lymphoid growth factor, J. Exp. Med., 192, 671, 10.1084/jem.192.5.671 Reche, 2001, Human thymic stromal lymphopoietin preferentially stimulates myeloid cells, J. Immunol., 167, 336, 10.4049/jimmunol.167.1.336 Quentmeier, 2001, Cloning of human thymic stromal lymphopoietin (TSLP) and signaling mechanisms leading to proliferation, Leukemia, 15, 1286, 10.1038/sj.leu.2402175 Liu, 2006, Thymic stromal lymphopoietin: master switch for allergic inflammation, J. Exp. Med., 203, 269, 10.1084/jem.20051745 Liu, 2007, Thymic stromal lymphopoietin and OX40 ligand pathway in the initiation of dendritic cell-mediated allergic inflammation, J. Allergy Clin. Immunol., 120, 238, 10.1016/j.jaci.2007.06.004 Saenz, 2008, Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites, Immunol. Rev., 226, 172, 10.1111/j.1600-065X.2008.00713.x Ziegler, 2010, The role of thymic stromal lymphopoietin (TSLP) in allergic disorders, Curr. Opin. Immunol., 22, 795, 10.1016/j.coi.2010.10.020 Ziegler, 2010, Sensing the outside world: TSLP regulates barrier immunity, Nat. Immunol., 11, 289, 10.1038/ni.1852 Jiang, 2006, Delayed functional maturation of natural regulatory T cells in the medulla of postnatal thymus: role of TSLP, BMC Immunol., 7, 6, 10.1186/1471-2172-7-6 Feinen, 2010, Critical role of Th17 responses in a murine model of Neisseria gonorrhoeae genital infection, Mucosal Immunol., 3, 312, 10.1038/mi.2009.139 Imarai, 2008, Regulatory T cells are locally induced during intravaginal infection of mice with Neisseria gonorrhoeae, Infect Immun., 76, 5456, 10.1128/IAI.00552-08 Wu, 2010, Functional regulation of thymic stromal lymphopoietin on proliferation and invasion of trophoblasts in human first-trimester pregnancy, Hum. Reprod., 25, 1146, 10.1093/humrep/deq051 Spadoni, 2012, Dendritic cells produce TSLP that limits the differentiation of Th17 cells, fosters Treg development, and protects against colitis, Mucosal Immunol., 5, 184, 10.1038/mi.2011.64 Jerse, 1999, Experimental gonococcal genital tract infection and opacity protein expression in estradiol-treated mice, Infect. Immun., 67, 5699, 10.1128/IAI.67.11.5699-5708.1999 Nomanbhoy, 2002, Vaginal and oral epithelial cell anti-Candida activity, Infect. Immun., 70, 7081, 10.1128/IAI.70.12.7081-7088.2002 Liu, 2011, Diversion of the immune response to Neisseria gonorrhoeae from Th17 to Th1/Th2 by treatment with anti-transforming growth factor β antibody generates immunological memory and protective immunity, mBio, 2, 10.1128/mBio.00095-11 Ouyang, 2008, The biological functions of T helper 17 cell effector cytokines in inflammation, Immunity, 28, 454, 10.1016/j.immuni.2008.03.004 Kobayashi, 2008, The role of chemokines in neutrophil biology, Front Biosci., 13, 2400, 10.2741/2853 Aluvihare, 2004, Regulatory T cells mediate maternal tolerance to the fetus, Nat. Immunol., 5, 266, 10.1038/ni1037 Zenclussen, 2005, Abnormal T-cell reactivity against paternal antigens in spontaneous abortion: adoptive transfer of pregnancy-induced CD4+CD25+ T regulatory cells prevents fetal rejection in a murine abortion model, Am. J. Pathol., 166, 811, 10.1016/S0002-9440(10)62302-4 Miossec, 2009, IL-17 and Th17 cells in human infammatory diseases, Microbes Infect., 11, 625, 10.1016/j.micinf.2009.04.003 Ziegler, 2006, Thymic stromal lymphopoietin in normal and pathogenic T cell development and function, Nat. Immunol., 7, 709, 10.1038/ni1360 Lee, 2007, Inducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NFκB, J. Immunol., 104, 914 Zeuthen, 2008, Epithelial cells prime the immune response to an array of gut-derived commensals towards a tolerogenic phenotype through distinct actions of thymic stromal lymphopoietin and transforming growth factor-beta, Immunology, 123, 197, 10.1111/j.1365-2567.2007.02687.x Allakhverdi, 2007, Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells, J. Exp. Med., 204, 253, 10.1084/jem.20062211 Humphreys, 2008, IL-33, a potent inducer of adaptive immunity to intestinal nematodes, J. Immunol., 180, 2443, 10.4049/jimmunol.180.4.2443 Astrakhan, 2007, Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development, Nat. Immunol., 8, 522, 10.1038/ni1452 Chappaz, 2007, Increased TSLP availability restores T- and B-cell compartments in adult IL-7 deficient mice, Blood, 110, 3862, 10.1182/blood-2007-02-074245 Soumelis, 2002, Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP, Nat. Immunol., 3, 673, 10.1038/ni805 Sokol, 2008, A mechanism for the initiation of allergen-induced T helper type 2 responses, Nat. Immunol., 9, 310, 10.1038/ni1558