Production of itaconic acid using metabolically engineered Escherichia coli

Blumhoff, M. L., Steiger, M. G., Mattanovich, D., and Sauer, M. (2013) Targeting enzymes to the right compartment: Metabolic engineering for itaconic acid production by <i>Aspergillus niger. Metab. Eng</i>., <b>19</b>, 26−32.

Bonnarme, P., Gillet, B., Sepulchre, A. M., Role, C., Beloeil, J. C. et al. (1995) Itaconate biosynthesis in <i>Aspergillus terreus. J. Bacteriol</i>., <b>177</b>, 3573−3578.

Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. <i>Anal. Biochem</i>., <b>72</b>, 248−254.

Chen, B. P. and Hai, T. (1994) Expression vectors for affinity purification and radiolabeling of proteins using <i>Escherichia coli</i> as host. <i>Gene,</i> <b>139</b>, 73−75.

Cote-Sierra, J., Jongert, E., Bredan, A., Gautam, D. C., Parkhouse, M. et al. (1998) A new membrane-bound OprI lipoprotein expression vector. High production of heterologous fusion proteins in gram (－) bacteria and the implications for oral vaccination. <i>Gene,</i> <b>221</b>, 25−34.

Datsenko, K. A. and Wanner, B. L. (2000) One-step inactivation of chromosomal genes in <i>Escherichia coli</i> K-12 using PCR products. <i>Proc. Natl. Acad. Sci. USA,</i> <b>97</b>, 6640−6645.

Dwiarti, L., Yamane, K., Yamatani, H., Kahar, P., and Okabe, M. (2002) Purification and characterization of <i>cis</i>-aconitic acid decarboxylase from <i>Aspergillus terreus</i> TN484-M1. <i>J. Biosci. Bioeng</i>., <b>94</b>, 29−33.

Ishimoto, K., Arimoto, M., Okuda, T., Yamaguchi, S., Aso, Y. et al. (2012) Biobased polymers: Synthesis of graft copolymers and comb polymers using lactic acid macromonomer and properties of the product polymers. <i>Biomacromolecules,</i> <b>13</b>, 3757−3768.

Jantama, K., Haupt, M. J., Svoronos, S. A., Zhang, X., Moore, J. C. et al. (2008) Combining metabolic engineering and metabolic evolution to develop nonrecombinant strains of <i>Escherichia coli</i> C that produce succinate and malate. <i>Biotechnol. Bioeng</i>., <b>99</b>, 1140−1153.

Kabir, M. M. and Shimizu, K. (2004) Metabolic regulation analysis of <i>icd</i>-gene knockout <i>Escherichia coli</i> based on 2D electrophoresis with MALDI-TOF mass spectrometry and enzyme activity measurements. <i>Appl. Microbiol. Biotechnol</i>., <b>65</b>, 84−96.

Kanamasa, S., Dwiarti, L., Okabe, M., and Park, E. Y. (2008) Cloning and functional characterization of the <i>cis</i>-aconitic acid decarboxylase (CAD) gene from <i>Aspergillus terreus. Appl. Microbiol. Biotechnol</i>., <b>80</b>, 223−229.

Kobayashi, T. and Nakamura, I. (1964) Dynamics in mycelia concentration of <i>A. terreus</i> K26 in steady state of continuous culture. <i>J. Ferment. Technol</i>., <b>44</b>, 264−274.

Li, A., van Luijk, N., ter Beek, M., Caspers, M., Punt, P. et al. (2011) A clone-based transcriptomics approach for the identification of genes relevant for itaconic acid production in <i>Aspergillus. Fungal Genet. Biol</i>., <b>48</b>, 602−611.

Li, A., Pfelzer, N., Zuijderwijk, R., and Punt, P. (2012) Enhanced itaconic acid production in <i>Aspergillus niger</i> using genetic modification and medium optimization. <i>BMC Biotechnol</i>., <b>12</b>, 57.

Lin, Y. H., Li, Y. F., Huang, M. C., and Tsai, Y. C. (2004) Intracellular expression of <i>Vitreoscilla</i> hemoglobin in <i>Aspergillus terreus</i> to alleviate the effect of a short break in aeration during culture. <i>Biotechnol. Lett</i>., <b>26</b>, 1067−1072.

Milson, P. E. and Meers, J. L. (1985) Gluconic and itaconic acid. <i>In</i> Comprehensive Biotechnology, Vol. 3, The Practice of Biotechnology, ed. by Blanch, H. W., Drew, S., and Wang, D. I., Pergamon Press, Oxford, pp. 681−700.

Okabe, M., Lies, D., Kanamasa, S., and Park, E. Y. (2009) Biotechnological production of itaconic acid and its biosynthesis in <i>Aspergillus terreus. Appl. Microbiol. Biotechnol</i>., <b>84</b>, 597−606.

Okabe, M., Ohta, N., and Park, Y. (1993) Itaconic acid production in an airlift bioreactor using a modified draft tube. <i>J. Ferment. Bioeng</i>., <b>76</b>, 117−122.

Okuda, T., Ishimoto, K., Ohara, H., and Kobayashi, S. (2012) Renewable biobased polymeric materials: Facile synthesis of itaconic anhydride-based copolymers with poly(L-lactic acid) grafts. <i>Macromolecules,</i> <b>45</b>, 4166−4174.

Park, Y., Itida, M., Ohta, N., and Okabe, M. (1994) Itaconic acid production using an air-lift bioreactor in repeated batch culture of <i>Aspergillus terreus. J. Ferment. Bioeng</i>., <b>77</b>, 329−331.

Riscaldati, E., Moresi, M., Federici, F., and Petruccioli, M. (2000) Effect of pH and stirring rate on itaconate production by <i>Aspergillus terreus. Biotechnol. J</i>., <b>83</b>, 219−230.

Sambrook, J. and Russell, D. W. (2001) Molecular Cloning: A Laboratory Manual, 3rd ed., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.

Schomburg, I., Chang, A., Placzek, S., Söhngen, C., Rother, M. et al. (2013) BRENDA in 2013: Integrated reactions, kinetic data, enzyme function data, improved disease classification: New options and contents in BRENDA. <i>Nucleic Acids Res</i>., <b>41</b>, D764−D772.

van der Straat, L., Vernooij, M., Lammers, M., van den Berg, W., Schonewille, T. et al. (2014) Expression of the <i>Aspergillus terreus</i> itaconic acid biosynthesis cluster in <i>Aspergillus niger. Microb. Cell Fact</i>., <b>13</b>, 11.

Tate, B. E. (1981) Itaconic acid and derivatives. Kirk-Othmer. <i>In</i> Encycl. Chem. Technol., Vol. 13, 3rd ed., ed. by Mark, H. F., Othmer, D. F., Overberger, C. G., and Seaborg, G. T., Wiley, New York, pp. 865−873.

Tevz, G., Bencina, M., and Legiša, M. (2010) Enhancing itaconic acid production by <i>Aspergillus terreus. Appl. Microbiol. Biotechnol</i>., <b>87</b>, 1657−1664.

Träger, M., Qazi, G. N., Onken, U., and Chopra, C. L. (1989) Comparison of airlift and stirred reactors for fermentation with <i>Aspergillus niger. J. Ferment. Bioeng</i>., <b>68</b>, 112−116.

Wagner, C., Odom, R., and Briggs, W. T. (1972) The uptake of acetate by <i>Escherichia coli</i> w. <i>Biochem. Biophys. Res. Commun</i>., <b>47</b>, 1036−1043.

Walden, W. E. (2002) From bacteria to mitochondria: Aconitase yields surprises. <i>Proc. Natl. Acad. Sci. USA,</i> <b>99</b>, 4138−4140.

Willke, T. and Vorlop, K. D. (2001) Biotechnological production of itaconic acid. <i>Appl. Microbiol. Biotechnol</i>., <b>56</b>, 289−295.

Wolfe, A. J. (2005) The acetate switch. <i>Microbiol. Mol. Biol. Rev</i>., <b>69</b>, 12−50.

Yahiro, K., Takahama, T., Jia, S., Park, Y., and Okabe, M. (1997) Comparison of air-lift and stirred tank reactors for itaconic acid production by <i>Aspergillus terreus. Biotechnol. Lett</i>., <b>19</b>, 619−621.

Yahiro, K., Takahama, T., Park, Y., and Okabe, M. (1995) Breeding of <i>Aspergillus terreus</i> mutant TN-484 for an itaconic acid production with high yield. <i>J. Ferm. Bioeng</i>., <b>79</b>, 506−508.

Yu, C., Cao, Y., Zou, H., and Xian, M. (2011) Metabolic engineering of <i>Escherichia coli</i> for biotechnological production of high-value organic acids and alcohols. <i>Appl. Microbiol. Biotechnol</i>., <b>89</b>, 573−583.