Harry W. Schroeder1, William H. Kelton1
1Agriculture Research Service, Southern Region, College Station, Texas 77840
Tóm tắt
Sterigmatocystin was produced by 59% of
Aspergillus flavus
cultures and by 16% of
A. parasiticus
cultures. All sterigmatocystin-producing cultures of the
A. flavus
group also simultaneously produced aflatoxin or
O
-methylsterigmatocystin. Sterigmatocystin was produced by
A. chevalieri, A. ruber
, and
A. amstelodami
, species not previously reported to produce the compound. In 5-day-old chicken embryos, the no-effect level of toxicity of sterigmatocystin was between 1 and 2 μg/egg; the mean lethal dose was 5 to 7 μg; and 90 to 100% of the embryos were killed with 10 μg. Teratogenic effects and weight reduction were generally associated with nonlethal doses.