Probiotic VSL#3 prevents antibiotic-associated diarrhoea in a double-blind, randomized, placebo-controlled clinical trial

Cremonini, 2002, Meta-analysis: the effect of probiotic administration on antibiotic-associated diarrhoea, Aliment Pharmacol Ther, 16, 1461, 10.1046/j.1365-2036.2002.01318.x Kelly, 1994, Clostridium difficile colitis, N Engl J Med, 330, 257, 10.1056/NEJM199401273300406 Kelly, 1998, Clostridium difficile infection, Annu Rev Med, 49, 375, 10.1146/annurev.med.49.1.375 Chandler, 2007, Clostridium difficile-associated disease in Oregon: increasing incidence and hospital-level risk factors, Infect Control Hosp Epidemiol, 28, 116, 10.1086/511795 Pépin, 2005, Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficile-associated diarrhea: a cohort study during an epidemic in Quebec, Clin Infect Dis, 41, 1254, 10.1086/496986 Kuijper, 2008, Update of Clostridium difficile infection due to PCR ribotype 027 in Europe, 2008, Euro Surveill, 13, 10.2807/ese.13.31.18942-en Health Protection Agency, 2009 Herath, 2008, Who consumes functional foods and nutraceuticals in Canada? Results of cluster analysis of the 2006 survey of Canadians' demand for food products supporting health and wellness, Appetite, 51, 256, 10.1016/j.appet.2008.02.018 Hempel, 2012, Probiotics for the prevention and treatment of antibiotic-associated diarrhea: a systematic review and meta-analysis, JAMA, 307, 1959, 10.1001/jama.2012.3507 Videlock, 2012, Meta-analysis: probiotics in antibiotic-associated diarrhoea, Aliment Pharmacol Ther, 35, 1355, 10.1111/j.1365-2036.2012.05104.x Plummer, 2004, Clostridium difficile pilot study: effects of probiotic supplementation on the incidence of C. difficile diarrhoea, Int Microbiol, 7, 59 Hickson, 2007, Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial, BMJ, 335, 80, 10.1136/bmj.39231.599815.55 Health Protection Agency, 2011 Dial, 2004, Risk of Clostridium difficile diarrhea among hospital inpatients prescribed proton pump inhibitors: cohort and case–control studies, Can Med Am J, 171, 33, 10.1503/cmaj.1040876 Frohmader, 2010, Decrease in frequency of liquid stool in enterally fed critically ill patients given the multispecies probiotic VSL#3: a pilot trial, Am J Crit Care, 19, e1, 10.4037/ajcc2010976 Hickson, 2011, Probiotics in the prevention of antibiotic-associated diarrhoea and Clostridium difficile infection, Therap Adv Gastroenterol, 4, 185, 10.1177/1756283X11399115 Pozzoni, 2012, Saccharomyces boulardii for the prevention of antibiotic-associated diarrhea in adult hospitalized patients: a single-center, randomized, double-blind, placebo-controlled trial, Am J Gastroenterol, 107, 922, 10.1038/ajg.2012.56 Stone, 2012, Evaluation of the national Cleanyourhands campaign to reduce Staphylococcus aureus bacteraemia and Clostridium difficile infection in hospitals in England and Wales by improved hand hygiene: four year, prospective, ecological, interrupted time series study, BMJ, 344, e3005, 10.1136/bmj.e3005 Morrow, 2010, Probiotic prophylaxis of ventilator-associated pneumonia: a blinded, randomized, controlled trial, Am J Respir Crit Care Med, 182, 1058, 10.1164/rccm.200912-1853OC