Pro-inflammatory effects of the Th1 chemokine CXCL10 in acquired aplastic anaemia

Cytokine - Tập 94 - Trang 45-51 - 2017
Junhong Li1, Meili Ge1, Shihong Lu1, Jun Shi1, Xingxin Li1, Min Wang1, Jinbo Huang1, Yingqi Shao1, Zhendong Huang1, Jing Zhang1, Neng Nie1, Yizhou Zheng1
1State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, PR China

Tài liệu tham khảo

Dolberg, 2014, Idiopathic aplastic anaemia: diagnosis and classification, Autoimmun. Rev., 13, 569, 10.1016/j.autrev.2014.01.014 Young, 2008, The epidemiology of acquired aplastic anaemia, Haematologica, 93, 489, 10.3324/haematol.12855 Young, 2013, Current concepts in the pathophysiology and treatment of aplastic anaemia, Hematol. Am. Soc. Hematol. Educ. Program., 76, 10.1182/asheducation-2013.1.76 Killick, 2016, Guidelines for the diagnosis and management of adult aplastic anaemia, Br. J. Haematol., 172, 187, 10.1111/bjh.13853 Dufour, 2001, Interferon gamma and tumour necrosis factor alpha are overexpressed in bone marrow T lymphocytes from paediatric patients with aplastic anaemia, Br. J. Haematol., 115, 1023, 10.1046/j.1365-2141.2001.03212.x Tsuda, 2000, Type I and type II T-cell profiles in aplastic anaemia and refractory anaemia, Am. J. Hematol., 64, 271, 10.1002/1096-8652(200008)64:4<271::AID-AJH6>3.0.CO;2-C de Latour, 2010, Th17 immune responses contribute to the pathophysiology of aplastic anaemia, Blood, 116, 4175, 10.1182/blood-2010-01-266098 Shi, 2012, Intrinsic impairment of CD4 (+) CD25 (+) regulatory T cells in acquired aplastic anaemia, Blood, 120, 1624, 10.1182/blood-2011-11-390708 Li, 2010, Abnormal immunity and stem/progenitor cells in acquired aplastic anaemia, Crit. Rev. Oncol. Hematol., 75, 79, 10.1016/j.critrevonc.2009.12.001 Feng, 2011, Cytokine signature profiles in acquired aplastic anaemia and myelodysplastic syndromes, Haematologica, 96, 602, 10.3324/haematol.2010.030536 Gidvani, 2007, Cytokine gene polymorphisms in acquired bone marrow failure, Am. J. Hematol., 82, 721, 10.1002/ajh.20881 Hosokawa, 2015, Identification of novel microRNA signatures linked to acquired aplastic anaemia, Haematologica, 100, 1534, 10.3324/haematol.2015.126128 Young, 2008, Aplastic anemia, Curr. Opin. Hematol., 15, 162, 10.1097/MOH.0b013e3282fa7470 Karin, 2016, Biased signalling pathways via CXCR3 control the development and function of CD4+ T cell subsets, J. Leukoc. Biol., 99, 857, 10.1189/jlb.2MR0915-441R Zlotnik, 2000, Chemokines: a new classification system and their role in immunity, Immunity, 12, 121, 10.1016/S1074-7613(00)80165-X Moser, 2004, Chemokines: multiple levels of leukocyte migration control, Trends Immunol., 25, 75, 10.1016/j.it.2003.12.005 Smit, 2003, CXCR3-mediated chemotaxis of human T cells is regulated by a Gi- and phospholipase C-dependent pathway and not via activation of MEK/p44/p42 MAPK nor Akt/PI-3 kinase, Blood, 102, 1959, 10.1182/blood-2002-12-3945 Shibata, 2010, Possible roles of IL-27 in the pathogenesis of psoriasis, J. Invest. Dermatol., 130, 1034, 10.1038/jid.2009.349 Ferrari, 2015, CXCL10 in psoriasis, Adv. Med. Sci., 60, 349, 10.1016/j.advms.2015.07.011 Antonelli, 2014, Chemokine (C-X-C motif) ligand (CXCL) 10 in autoimmune diseases, Autoimmun. Rev., 13, 272, 10.1016/j.autrev.2013.10.010 Angiolillo, 1995, Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo, J. Exp. Med., 182, 155, 10.1084/jem.182.1.155 Antonelli, 2014, CXCR3, CXCL10 and type 1 diabetes, Cytokine Growth Factor Rev., 25, 57, 10.1016/j.cytogfr.2014.01.006 Lee, 2013, The interaction between CXCL10 and cytokines in chronic inflammatory arthritis, Autoimmun. Rev., 12, 554, 10.1016/j.autrev.2012.10.001 Lacotte, 2009, CXCR3, inflammation, and autoimmune diseases, Ann. NY Acad. Sci., 1173, 310, 10.1111/j.1749-6632.2009.04813.x Antonelli, 2008, High values of CXCL10 serum levels in mixed cryoglobulinemia associated with hepatitis C infection, Am. J. Gastroenterol., 103, 2488, 10.1111/j.1572-0241.2008.02040.x Altara, 2016, The CXCL10/CXCR3 axis and cardiac inflammation: implications for immunotherapy to treat infectious and noninfectious diseases of the heart, J. Immunol. Res., 4396368 Antonelli, 2012, Variable modulation by cytokines and thiazolidinediones of the prototype Th1 chemokine CXCL10 in anaplastic thyroid cancer, Cytokine, 59, 218, 10.1016/j.cyto.2012.04.042 Camitta, 1979, A prospective study of androgens and bone marrow transplantation for treatment of severe aplastic anaemia, Blood, 53, 504, 10.1182/blood.V53.3.504.504 Rashighi, 2015, Interfering with the IFN-gamma/CXCL10 pathway to develop new targeted treatments for vitiligo, Ann. Transl. Med., 3, 343 Welcher, 2015, Blockade of interferon-gamma normalizes interferon-regulated gene expression and serum CXCL10 levels in patients with systemic lupus erythematosus, Arthritis Rheumatol., 67, 2713, 10.1002/art.39248 Osborn, 1990, Leukocyte adhesion to endothelium in inflammation, Cell, 62, 3, 10.1016/0092-8674(90)90230-C Spertini, 1991, Regulation of leukocyte migration by activation of the leukocyte adhesion molecule-1 (LAM-1) selectin, Nature, 349, 691, 10.1038/349691a0 Springer, 1990, Adhesion receptors of the immune system, Nature, 346, 425, 10.1038/346425a0 Youssef, 2000, C-C chemokine-encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis, J. Clin. Invest., 106, 361, 10.1172/JCI9109 Wildbaum, 2002, Plasmid DNA encoding IFN-inducible protein 10 redirects antigen-specific T cell polarization and suppresses experimental autoimmune encephalomyelitis, J. Immunol., 168, 5885, 10.4049/jimmunol.168.11.5885 Zohar, 2014, CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis, J. Clin. Invest., 124, 2009, 10.1172/JCI71951 Antonelli, 2015, The role of the Th1 chemokine CXCL10 in vitiligo, Ann. Transl. Med., 3, S16 Corbisier, 2015, Biased signalling at chemokine receptors, J. Biol. Chem., 290, 9542, 10.1074/jbc.M114.596098 Steen, 2013, Biased and constitutive signalling in the CC-chemokine receptor CCR5 by manipulating the interface between transmembrane helices 6 and 7, J. Biol. Chem., 288, 12511, 10.1074/jbc.M112.449587 Martinelli, 2001, The CC chemokine eotaxin (CCL11) is a partial agonist of CC chemokine receptor 2b, J. Biol. Chem., 276, 42957, 10.1074/jbc.M103933200 Lin, 2014, IFN-γ causes aplastic anaemia by altering hematopoietic stem/progenitor cell composition and disrupting lineage differentiation, Blood, 124, 3699, 10.1182/blood-2014-01-549527 Solomou, 2006, T-bet, a Th1 transcription factor, is up-regulated in T cells from patients with aplastic anaemia, Blood, 107, 3983, 10.1182/blood-2005-10-4201 Kordasti, 2012, Functional characterization of CD4+ T cells in aplastic anaemia, Blood, 119, 2033, 10.1182/blood-2011-08-368308