Prioritization of novel ADPKD drug candidates from disease-stage specific gene expression profiles

EBioMedicine - Tập 51 - Trang 102585 - 2020
Tareq B. Malas1, Wouter N. Leonhard1, Hester Bange2, Zoraide Granchi3, Kristina M. Hettne1, Gerard J.P. Van Westen4, Leo S. Price2, Peter A.C. 't Hoen1,5, Dorien J.M. Peters1
1Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands
2OcellO B.V., Leiden, The Netherlands
3GenomeScan B.V., Plesmanlaan 1/D, 2333 BZ Leiden, the Netherlands
4Drug Discovery and Safety, Leiden Academic Center for Drug Research, Einsteinweg 55, 2333 CC, Leiden, the Netherlands
5Center for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center Nijmegen, Nijmegen, the Netherlands

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